<SUBMISSION>
<ACCESSION-NUMBER>0001181431-08-017989
<TYPE>4
<PUBLIC-DOCUMENT-COUNT>1
<PERIOD>20080307
<FILING-DATE>20080311
<DATE-OF-FILING-DATE-CHANGE>20080311
<ISSUER>
<COMPANY-DATA>
<CONFORMED-NAME>ACADIA PHARMACEUTICALS INC
<CIK>0001070494
<ASSIGNED-SIC>2834
<IRS-NUMBER>061376651
<STATE-OF-INCORPORATION>DE
<FISCAL-YEAR-END>1231
</COMPANY-DATA>
<BUSINESS-ADDRESS>
<STREET1>3911 SORRENTO VALLEY BLVD
<CITY>SAN DIEGO
<STATE>CA
<ZIP>92121
<PHONE>858-558-2871
</BUSINESS-ADDRESS>
<MAIL-ADDRESS>
<STREET1>3911 SORRENTO VALLEY BLVD
<CITY>SAN DIEGO
<STATE>CA
<ZIP>92121
</MAIL-ADDRESS>
</ISSUER>
<REPORTING-OWNER>
<OWNER-DATA>
<CONFORMED-NAME>Lundstrom Brian
<CIK>0001309849
</OWNER-DATA>
<FILING-VALUES>
<FORM-TYPE>4
<ACT>34
<FILE-NUMBER>000-50768
<FILM-NUMBER>08682069
</FILING-VALUES>
<BUSINESS-ADDRESS>
<PHONE>858.558-2871
</BUSINESS-ADDRESS>
<MAIL-ADDRESS>
<STREET1>3911 SORRENTO VALLEY BOULEVARD
<CITY>SAN DIEGO
<STATE>CA
<ZIP>92121
</MAIL-ADDRESS>
</REPORTING-OWNER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>rrd199151.xml
<DESCRIPTION>FORM 4  -- ANNUAL GRANT 7MAR08
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2008-03-07</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0001070494</issuerCik>
        <issuerName>ACADIA PHARMACEUTICALS INC</issuerName>
        <issuerTradingSymbol>ACAD</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001309849</rptOwnerCik>
            <rptOwnerName>Lundstrom Brian</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>3911 SORRENTO VALLEY BOULEVARD</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>SAN DIEGO</rptOwnerCity>
            <rptOwnerState>CA</rptOwnerState>
            <rptOwnerZipCode>92121</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>Sr. VP, Bus. Development</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <derivativeTable>
        <derivativeTransaction>
            <securityTitle>
                <value>Stock option (right to buy)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>8.32</value>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2008-03-07</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>A</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>16000</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <footnoteId id="F1"/>
            </exerciseDate>
            <expirationDate>
                <value>2018-03-06</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>16000</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>16000</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeTransaction>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">25% of the shares subject to the Stock Option vest and become exercisable on March 7, 2009. The remaining shares vest and become exercisable thereafter in 36 equal monthly installments.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Glenn F. Baity, attorney-in-fact</signatureName>
        <signatureDate>2008-03-11</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SUBMISSION>
