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Selected Quarterly Financial Data (Unaudited) (Tables) | 12 Months Ended
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Dec. 31, 2017
Quarterly Financial Information Disclosure [Abstract] |
Selected Quarterly Financial Data |
|  | Fiscal Year 2017 Quarters |  |  |  |  |
|  | 1st |  |  | 2nd |  |  | 3rd |  |  | 4th |  |  | Total |
Revenues(1) |  | $ | 15,286 |  |  | $ | 30,475 |  |  | $ | 35,578 |  |  | $ | 43,562 |  |  | $ | 124,901 |
Gross profit(2) |  | $ | 13,023 |  |  | $ | 28,251 |  |  | $ | 33,443 |  |  | $ | 41,107 |  |  | $ | 115,824 |
Net loss |  | $ | (87,843 | ) |  | $ | (67,441 | ) |  | $ | (65,248 | ) |  | $ | (68,871 | ) |  | $ | (289,403 | )
Basic and diluted net loss per share(3) |  | $ | (0.72 | ) |  | $ | (0.55 | ) |  | $ | (0.53 | ) |  | $ | (0.55 | ) |  | $ | (2.36 | )
|  | Fiscal Year 2016 Quarters |  |  |  |  |
|  | 1st |  |  | 2nd |  |  | 3rd |  |  | 4th |  |  | Total |
Revenues(1) |  | $ | 4 |  |  | $ | 97 |  |  | $ | 5,268 |  |  | $ | 11,962 |  |  | $ | 17,331 |
Gross profit(2) |  | $ | — |  |  | $ | (429 | ) |  | $ | 4,423 |  |  | $ | 10,258 |  |  | $ | 14,252 |
Net loss |  | $ | (49,762 | ) |  | $ | (71,322 | ) |  | $ | (71,613 | ) |  | $ | (78,696 | ) |  | $ | (271,393 | )
Basic and diluted net loss per share(3) |  | $ | (0.45 | ) |  | $ | (0.63 | ) |  | $ | (0.61 | ) |  | $ | (0.65 | ) |  | $ | (2.34 | )
(1) | The Company commenced commercial sales of NUPLAZID in May 2016. The quarters after March 31, 2016 reflect net product revenue related to NUPLAZID.
(2) | Determined by subtracting cost of product sales from product sales, net.
(3) | Net loss per common share, basic and diluted, are computed independently for each quarter and the full year based upon respective average shares outstanding. Therefore, the sum of the quarterly net loss per common share amounts may not equal the annual amounts reported.

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- Definition Tabular disclosure of quarterly financial data. Includes, but is not limited to, financial information for fiscal quarters, cumulative effect of a change in accounting principle and earnings per share data. + References Reference 1: http://www.xbrl.org/2003/role/presentationRef -Publisher FASB -Name Accounting Standards Codification -Topic 270 -SubTopic 10 -Section 50 -Paragraph 1 -Subparagraph (a)-(j) -URI http://asc.fasb.org/extlink&oid=84173487&loc=d3e1280-108306 + Details
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