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Income Taxes - Additional Information (Detail) - USD ($) | 12 Months Ended
--- | ---
Dec. 31, 2018 | Dec. 31, 2017 | Dec. 31, 2016 | Dec. 31, 2015
Income Tax [Line Items] |  |  |  |
State income tax provision |  | $ 1,100,000 | $ 1,300,000 | $ 300,000
Federal R&D credit carryforwards |  | 19,800,000 |  |
Increase in valuation allowance of deferred tax assets |  | 10,200,000 |  |
Deferred tax benefit or expense related to remeasurement of deferred tax assets and liabilities |  | 0 |  |
Unrecognized tax reserves recorded during period |  | 361,000 | 363,000 | 2,301,000
Interest and/or penalties accrued |  | 0 | 0 |
Tax cuts and jobs act provisional adjustment |  | 1,092,000 |  |
Interest and/or penalties |  | 0 | $ 0 | $ 0
Scenario Forecast |  |  |  |
Income Tax [Line Items] |  |  |  |
Tax rate | 21.00% |  |  |
Remeasurement of deferred tax balance | $ 68,900,000 |  |  |
Federal |  |  |  |
Income Tax [Line Items] |  |  |  |
Operating loss carryforwards |  | $ 407,100,000 |  |
Remaining net operating loss carryforward, expiration year |  | 2023 |  |
Federal | Expiring in 2018 |  |  |  |
Income Tax [Line Items] |  |  |  |
Operating loss carryforwards |  | $ 2,300,000 |  |
State |  |  |  |
Income Tax [Line Items] |  |  |  |
Operating loss carryforwards |  | $ 340,000,000 |  |
Remaining net operating loss carryforward, expiration year |  | 2023 |  |
Research and development credit carryforwards with no expiration date |  | $ 10,000,000 |  |
State | Expiring in 2018 | Maximum |  |  |  |
Income Tax [Line Items] |  |  |  |
Operating loss carryforwards |  | 100,000 |  |
State | Expiring in 2023 |  |  |  |
Income Tax [Line Items] |  |  |  |
Net operating loss carryforwards with no expiration date |  | 200,000 |  |
Foreign |  |  |  |
Income Tax [Line Items] |  |  |  |
Operating loss carryforwards |  | 647,400,000 |  |
Net operating loss carryforwards with no expiration date |  | 3,600,000 |  |
Foreign | Operating Loss Carryforwards Expiring 2022 |  |  |  |
Income Tax [Line Items] |  |  |  |
Operating loss carryforwards |  | 643,900,000 |  |
Expire in 2018 |  |  |  |
Income Tax [Line Items] |  |  |  |
Federal R&D credit carryforwards |  | $ 100,000 |  |

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