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Balance Sheet Details - Schedule of Accrued Liabilities (Detail) - USD ($) $ in Thousands	Jun. 30, 2019	Dec. 31, 2018
Payables And Accruals [Abstract]
Accrued compensation and benefits	$ 15,321	$ 17,028
Accrued research and development services	13,285	10,367
Accrued sales allowances	12,485	5,849
Accrued consulting and professional fees	10,324	19,325
Current portion of lease liabilities	4,412
Accrued royalties	1,677	1,200
Other	1,660	2,629
Accrued liabilities	$ 59,164	$ 56,398

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