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Balance Sheet Details - Schedule of Accrued Liabilities (Detail) - USD ($) $ in Thousands	Sep. 30, 2019	Dec. 31, 2018
Payables And Accruals [Abstract]
Accrued compensation and benefits	$ 18,540	$ 17,028
Accrued research and development services	14,964	10,367
Accrued consulting and professional fees	14,831	19,325
Accrued sales allowances	8,182	5,849
Current portion of lease liabilities	3,889
Accrued royalties	1,917	1,200
Other	1,977	2,629
Accrued liabilities	$ 64,300	$ 56,398

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