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Commitments and Contingencies - Additional Information (Detail) - USD ($)	1 Months Ended		12 Months Ended
	Aug. 31, 2018	May 31, 2018	Dec. 31, 2019	Dec. 31, 2018	Dec. 31, 2017	Dec. 31, 2016
Other Commitments [Line Items]
Gain (loss) on strategic investments			$ 997,000	$ (1,840,000)
Restricted cash			4,787,000	4,826,000	$ 2,475,000
Corporate Credit Card Program | Letter of Credit
Other Commitments [Line Items]
Restricted cash						$ 2,000,000.0
Corporate Fleet Program | Letter of Credit
Other Commitments [Line Items]
Restricted cash			400,000
Other assets
Other Commitments [Line Items]
Aggregate carrying amount of strategic equity investment			2,300,000	1,300,000
Other expense
Other Commitments [Line Items]
Gain (loss) on strategic investments			$ 1,000,000.0	(1,800,000)
Exclusivity Deed | Neuren
Other Commitments [Line Items]
Aggregate carrying amount of strategic equity investment		$ 3,100,000
Shares subscribed		1,330,000
Exclusivity Deed | Neuren | Sales, general and administrative
Other Commitments [Line Items]
Payments for exclusive right		$ 900,000
License Agreements | Neuren | North America
Other Commitments [Line Items]
Upfront payment	$ 10,000,000.0
License Agreements | Neuren | Research and development | North America
Other Commitments [Line Items]
Upfront payment				$ 10,000,000.0
Maximum
Other Commitments [Line Items]
Percentage of royalty payments obligation on net product sales			2.00%
Maximum | License Agreements | Neuren | North America
Other Commitments [Line Items]
Milestone payments payable	$ 455,000,000.0

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