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Selected Quarterly Financial Data (Unaudited) - Selected Quarterly Financial Data (Detail) - USD ($)
$ / shares in Units, $ in Thousands
 3 Months Ended 12 Months Ended
Dec. 31, 2019
Sep. 30, 2019
Jun. 30, 2019
Mar. 31, 2019
Dec. 31, 2018
Sep. 30, 2018
Jun. 30, 2018
Mar. 31, 2018
Dec. 31, 2019
Dec. 31, 2018
Dec. 31, 2017
Quarterly Financial Information Disclosure [Abstract]                      
Revenues $ 98,326 $ 94,586 $ 83,205 $ 62,959 $ 59,571 $ 58,305 $ 57,063 $ 48,868 $ 339,076 $ 223,807  
Gross profit [1] 95,306 92,170 80,247 60,009 56,748 54,466 53,501 46,715 327,732 211,430  
Net loss $ (53,036) $ (41,978) $ (54,941) $ (85,304) $ (65,492) $ (62,138) $ (63,266) $ (54,296) $ (235,259) $ (245,192) $ (289,403)
Basic and diluted net loss per share $ (0.34) [2] $ (0.29) [2] $ (0.38) [2] $ (0.59) [2] $ (0.50) [2] $ (0.50) [2] $ (0.51) [2] $ (0.44) [2] $ (1.60) [2] $ (1.94) [2] $ (2.36)
[1] Determined by subtracting cost of product sales from product sales, net.
[2] Net loss per common share, basic and diluted, are computed independently for each quarter and the full year based upon respective average shares outstanding. Therefore, the sum of the quarterly net loss per common share amounts may not equal the annual amounts reported.