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Commitments and Contingencies - Additional Information (Detail) - USD ($)
1 Months Ended 3 Months Ended
Mar. 31, 2020
Aug. 31, 2018
May 31, 2018
Mar. 31, 2020
Mar. 31, 2019
Sep. 30, 2018
Dec. 31, 2019
Dec. 31, 2018
Other Commitments [Line Items]                
Obligation expiration year       2021        
Loss on strategic investment       $ 1,497,000 $ 229,000      
Restricted cash $ 5,770,000     5,770,000 4,787,000   $ 4,787,000 $ 4,826,000
Letter of Credit | Corporate Credit Card Program                
Other Commitments [Line Items]                
Restricted cash 2,000,000.0     2,000,000.0        
Letter of Credit | Fleet Program                
Other Commitments [Line Items]                
Restricted cash 400,000     400,000        
Other assets                
Other Commitments [Line Items]                
Aggregate carrying amount of strategic equity investment 800,000     800,000     $ 2,300,000  
Other expense                
Other Commitments [Line Items]                
Loss on strategic investment       1,500,000 $ 200,000      
Exclusivity Deed | Neuren                
Other Commitments [Line Items]                
Aggregate carrying amount of strategic equity investment     $ 3,100,000          
Shares subscribed     1,330,000          
Exclusivity Deed | Neuren | Selling, general and administrative                
Other Commitments [Line Items]                
Payments for exclusive right     $ 900,000          
License Agreements | Neuren | North America                
Other Commitments [Line Items]                
Upfront license fee 10,000,000.0 $ 10,000,000.0            
License Agreements | Neuren | Research and development | North America                
Other Commitments [Line Items]                
Upfront payment       $ 10,000,000.0   $ 10,000,000.0    
Maximum                
Other Commitments [Line Items]                
Percentage of royalty payments obligation on net product sales       2.00%        
Maximum | License Agreements | Neuren | North America                
Other Commitments [Line Items]                
Additional milestone payments payable $ 515,000,000.0 $ 455,000,000.0   $ 515,000,000.0