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Condensed Consolidated Statements of Stockholders' Equity (Unaudited) - USD ($)
$ in Thousands
Total
Common Stock
Additional Paid-in Capital
Accumulated Deficit
Other Comprehensive Income (Loss)
Beginning balance at Dec. 31, 2018 $ 479,079 $ 14 $ 1,948,300 $ (1,468,863) $ (372)
Issuance of common stock from exercise of stock options and units     55,127    
Issuance of common stock in public offering, net of issuance costs   1 271,462    
Issuance of common stock pursuant to employee stock purchase plan     2,199    
Stock-based compensation     62,852    
Net loss (182,223)     (182,223)  
Other comprehensive (loss) income 792        
Ending balance at Sep. 30, 2019 689,289 15 2,339,940 (1,651,086) 420
Beginning balance at Jun. 30, 2019 388,914 14 1,997,454 (1,609,108) 554
Issuance of common stock from exercise of stock options and units     48,504    
Issuance of common stock in public offering, net of issuance costs   1 271,462    
Stock-based compensation     22,520    
Net loss (41,978)     (41,978)  
Other comprehensive (loss) income (134)        
Ending balance at Sep. 30, 2019 689,289 15 2,339,940 (1,651,086) 420
Beginning balance at Dec. 31, 2019 699,135 15 2,402,945 (1,704,122) 297
Issuance of common stock in connection with merger agreement     44,280    
Issuance of common stock from exercise of stock options and units   1 58,899    
Issuance of common stock pursuant to employee stock purchase plan     3,970    
Stock-based compensation     63,194    
Net loss (214,824)     (214,824)  
Other comprehensive (loss) income 212        
Ending balance at Sep. 30, 2020 654,867 16 2,573,288 (1,918,946) 509
Beginning balance at Jun. 30, 2020 663,013 15 2,495,804 (1,834,286) 1,480
Issuance of common stock in connection with merger agreement     44,280    
Issuance of common stock from exercise of stock options and units   1 11,714    
Stock-based compensation     21,490    
Net loss (84,660)     (84,660)  
Other comprehensive (loss) income (971)        
Ending balance at Sep. 30, 2020 $ 654,867 $ 16 $ 2,573,288 $ (1,918,946) $ 509