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Commitments and Contingencies - Additional Information (Detail) - USD ($) shares in Millions	1 Months Ended			3 Months Ended			12 Months Ended
	Aug. 31, 2020	Mar. 31, 2020	Aug. 31, 2018	Mar. 31, 2021	Sep. 30, 2020	Mar. 31, 2020	Dec. 31, 2018	Dec. 31, 2020	Dec. 31, 2019
Other Commitments [Line Items]
Obligation expiration year				2021
Gain (loss) on strategic investment				$ 145,000		$ (1,497,000)
Restricted cash		$ 5,770,000		5,770,000		5,770,000		$ 5,770,000	$ 4,787,000
Letter of Credit | Corporate Credit Card Program
Other Commitments [Line Items]
Restricted cash				2,000,000.0
Letter of Credit | Fleet Program
Other Commitments [Line Items]
Restricted cash				400,000
Cersci Therapeutics
Other Commitments [Line Items]
Upfront consideration and transaction costs	$ 52,800,000
Upfront payment	$ 44,300,000
Upfront payment conditions	The Company incurred an aggregate of $52.8 million in upfront consideration and transaction costs, of which, $44.3 million was paid through the issuance of approximately 1.2 million shares of the Company’s common stock.
Common stock issuance	1.2
Cersci Therapeutics | Research and development
Other Commitments [Line Items]
Assets acquisition and upfront payment					$ 45,700,000
License Agreements
Other Commitments [Line Items]
Upfront payment				$ 0		10,000,000.0
License Agreements | Neuren | North America
Other Commitments [Line Items]
Upfront payment		10,000,000.0
Upfront license fee			$ 10,000,000.0
License Agreements | Neuren | Research and development | North America
Other Commitments [Line Items]
Upfront payment						10,000,000.0	$ 10,000,000.0
Maximum
Other Commitments [Line Items]
Percentage of royalty payments obligation on net product sales				2.00%
Mile stone payments payable				$ 2,200,000,000
Maximum | Cersci Therapeutics | Development Commercialization and Sales Milestones
Other Commitments [Line Items]
Compensation expense related to mergers to former holders	$ 887,000,000.0
Maximum | License Agreements | Neuren | North America
Other Commitments [Line Items]
Mile stone payments payable		$ 515,000,000.0	$ 455,000,000.0			$ 515,000,000.0

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