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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($)
$ in Thousands
 3 Months Ended
Mar. 31, 2021
Mar. 31, 2020
Cash flows from operating activities    
Net loss $ (66,448) $ (88,023)
Adjustments to reconcile net loss to net cash used in operating activities:    
Stock-based compensation 13,184 22,348
Amortization of premiums and accretion of discounts on investment securities 689 87
Amortization of intangible assets 370 370
(Gain) loss on strategic investment (145) 1,497
Depreciation 525 294
Changes in operating assets and liabilities:    
Accounts receivable, net (8,585) (5,855)
Interest and other receivables 1,477 (842)
Inventory (492) (37)
Prepaid expenses (2,821) (3,520)
Operating lease right-of-use assets 1,589 1,187
Other assets 10 18
Accounts payable 356 (599)
Accrued liabilities 2,761 24,057
Operating lease liabilities (1,052) (360)
Long-term liabilities (1,567) 376
Net cash used in operating activities (60,149) (49,002)
Cash flows from investing activities    
Purchases of investment securities (127,864) (100,773)
Maturities of investment securities 159,817 131,315
Purchases of property and equipment (1,076) (934)
Net cash provided by investing activities 30,877 29,608
Cash flows from financing activities    
Proceeds from issuance of common stock, net of issuance costs 7,726 3,754
Net cash provided by financing activities 7,726 3,754
Effect of exchange rate changes on cash 5 2
Net decrease in cash, cash equivalents and restricted cash (21,541) (15,638)
Cash, cash equivalents and restricted cash    
Beginning of period 331,798 194,467
End of period 310,257 178,829
Supplemental disclosure of noncash information:    
Property and equipment purchases in accounts payable and accrued liabilities $ 45 $ 1,269