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Balance Sheet Details - Schedule of Accrued Liabilities (Detail) - USD ($) $ in Thousands	Dec. 31, 2021	Dec. 31, 2020
Payables and Accruals [Abstract]
Accrued research and development services	$ 27,270	$ 28,380
Accrued compensation and benefits	25,896	25,811
Accrued sales allowances	15,717	14,115
Accrued consulting and professional fees	9,319	18,969
Current portion of lease liabilities	8,304	5,087
Other	2,686	5,112
Accrued liabilities	$ 89,192	$ 97,474

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Carrying amount as of the balance sheet date for expenses incurred related to clinical development activities due within one year.

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Carrying value as of the balance sheet date of obligations incurred and payable, pertaining to costs that are statutory in nature, are incurred on contractual obligations, or accumulate over time and for which invoices have not yet been received or will not be rendered. Examples include taxes, interest, rent and utilities. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer).

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Carrying value as of the balance sheet date of obligations incurred through that date and payable for professional fees, such as for legal and accounting services received. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer).

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