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v3.22.1

Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($) $ in Thousands | 3 Months Ended
--- | ---
Mar. 31, 2022 | Mar. 31, 2021
Cash flows from operating activities |  |
Net loss | $ (113,056) | $ (66,448)
Adjustments to reconcile net loss to net cash used in operating activities: |  |
Stock-based compensation | 14,963 | 13,184
Amortization of premiums and accretion of discounts on investment securities | 447 | 689
Amortization of intangible assets | 0 | 370
Gain on strategic investment | (339) | (145)
Depreciation | 516 | 525
Changes in operating assets and liabilities: |  |
Accounts receivable, net | 1,653 | (8,585)
Interest and other receivables | 209 | 1,477
Inventory | 833 | (492)
Prepaid expenses | (1,863) | (2,821)
Operating lease right-of-use assets | 1,522 | 1,589
Other assets |  | 10
Accounts payable | 3,892 | 356
Accrued liabilities | 19,672 | 2,761
Operating lease liabilities | (2,117) | (1,052)
Long-term liabilities | (2,661) | (1,567)
Net cash used in operating activities | (76,329) | (60,149)
Cash flows from investing activities |  |
Purchases of investment securities | 0 | (127,864)
Maturities of investment securities | 131,345 | 159,817
Purchases of property and equipment | 0 | (1,076)
Net cash provided by investing activities | 131,345 | 30,877
Cash flows from financing activities |  |
Proceeds from issuance of common stock, net of issuance costs | 2,467 | 7,726
Net cash provided by financing activities | 2,467 | 7,726
Effect of exchange rate changes on cash | 2 | 5
Net increase (decrease) in cash, cash equivalents and restricted cash | 57,485 | (21,541)
Cash, cash equivalents and restricted cash |  |
Beginning of period | 153,205 | 331,798
End of period | 210,690 | 310,257
Supplemental disclosure of noncash information: |  |
Property and equipment purchases in accounts payable and accrued liabilities | $ 0 | $ 45

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