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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($)
$ in Thousands
 3 Months Ended
Mar. 31, 2022
Mar. 31, 2021
Cash flows from operating activities    
Net loss $ (113,056) $ (66,448)
Adjustments to reconcile net loss to net cash used in operating activities:    
Stock-based compensation 14,963 13,184
Amortization of premiums and accretion of discounts on investment securities 447 689
Amortization of intangible assets 0 370
Gain on strategic investment (339) (145)
Depreciation 516 525
Changes in operating assets and liabilities:    
Accounts receivable, net 1,653 (8,585)
Interest and other receivables 209 1,477
Inventory 833 (492)
Prepaid expenses (1,863) (2,821)
Operating lease right-of-use assets 1,522 1,589
Other assets 10
Accounts payable 3,892 356
Accrued liabilities 19,672 2,761
Operating lease liabilities (2,117) (1,052)
Long-term liabilities (2,661) (1,567)
Net cash used in operating activities (76,329) (60,149)
Cash flows from investing activities    
Purchases of investment securities 0 (127,864)
Maturities of investment securities 131,345 159,817
Purchases of property and equipment 0 (1,076)
Net cash provided by investing activities 131,345 30,877
Cash flows from financing activities    
Proceeds from issuance of common stock, net of issuance costs 2,467 7,726
Net cash provided by financing activities 2,467 7,726
Effect of exchange rate changes on cash 2 5
Net increase (decrease) in cash, cash equivalents and restricted cash 57,485 (21,541)
Cash, cash equivalents and restricted cash    
Beginning of period 153,205 331,798
End of period 210,690 310,257
Supplemental disclosure of noncash information:    
Property and equipment purchases in accounts payable and accrued liabilities $ 0 $ 45