Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($) $ in Thousands	9 Months Ended
Sep. 30, 2022	Sep. 30, 2021
Cash flows from operating activities
Net loss	$ (174,250)	$ (124,776)
Adjustments to reconcile net loss to net cash used in operating activities:
Stock-based compensation	53,787	50,735
Amortization of premiums and accretion of discounts on investment securities	(642)	1,766
Amortization of intangible assets	0	1,108
Loss (gain) on strategic investment	(1,998)	(706)
Depreciation	1,537	1,701
Changes in operating assets and liabilities:
Accounts receivable, net	8,633	(12,449)
Interest and other receivables	575	1,063
Inventory	2,105	(4,427)
Prepaid expenses	899	1,072
Operating lease right-of-use assets	4,845	4,794
Other assets	(48)	11
Accounts payable	3,132	(771)
Accrued liabilities	17,771	(17,260)
Operating lease liabilities	(5,959)	(4,044)
Long-term liabilities	(568)	(357)
Net cash used in operating activities	(90,181)	(102,540)
Cash flows from investing activities
Purchases of investment securities	(269,626)	(453,847)
Maturities of investment securities	360,615	312,317
Purchases of property and equipment	0	(1,121)
Net cash provided by (used in) investing activities	90,989	(142,651)
Cash flows from financing activities
Proceeds from issuance of common stock, net of issuance costs	6,585	13,797
Net cash provided by financing activities	6,585	13,797
Effect of exchange rate changes on cash	14	6
Net increase (decrease) in cash, cash equivalents and restricted cash	7,407	(231,388)
Cash, cash equivalents and restricted cash
Beginning of period	153,205	331,798
End of period	$ 160,612	$ 100,410

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