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Summary of Company's Stock Option Activity (Detail)
$ / shares in Units, $ in Thousands
12 Months Ended
Dec. 31, 2022
USD ($)
$ / shares
shares
Number of Shares  
Options Outstanding, Beginning Balance | shares 15,086,141
Granted | shares 3,393,568
Exercised | shares (226,943)
Cancelled/forfeited | shares (1,913,301)
Options Outstanding, Ending Balance | shares 16,339,465
Vested at December 31, 2022 | shares 11,386,596
Unvested at December 31, 2022 | shares 4,952,869
Weighted Average Exercise Prices  
Weighted Average Exercise Prices, Beginning Balance | $ / shares $ 31.58
Weighted Average Exercise Prices, granted | $ / shares 22.79
Weighted Average Exercise Prices, exercised | $ / shares 16.32
Weighted Average Exercise Prices, Cancelled/forfeited | $ / shares 32.68
Weighted Average Exercise Prices, Ending Balance | $ / shares 29.83
Weighted Average Exercise Prices, Vested | $ / shares 30.70
Weighted Average Exercise Prices, Unvested | $ / shares $ 27.82
Weighted average remaining contractual term, Outstanding 5 years 8 months 12 days
Weighted average remaining contractual term, Vested 4 years 6 months
Weighted average remaining contractual term, Unvested 8 years 3 months 18 days
Aggregate Intrinsic Value, Outstanding | $ $ 1,052
Aggregate Intrinsic Value, Vested | $ 725
Aggregate Intrinsic Value, Unvested | $ $ 327