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Subsequent Event (Tables)
 6 Months Ended
Jun. 30, 2023
Subsequent Events [Abstract]  
Summary of Milestone Payments based on the achievement of certain Development and Sales Milestones the following additional milestone payments based on the achievement of certain development and sales milestones (in thousands):

 

 

Trofinetide

 

 

NNZ-2591

 

Development milestones

 

$

—

 

 

$

15,000

 

First commercial sale milestones

 

 

 

 

 

 

North America

 

 

—

 

 

 

40,000

 

Europe

 

 

45,000

 

 

 

45,000

 

Japan

 

 

18,750

 

 

 

18,750

 

Sales milestones

 

 

 

 

 

 

North America

 

 

—

 

 

 

350,000

 

Europe

 

 

170,000

 

 

 

170,000

 

Japan

 

 

110,000

 

 

 

110,000

 

Rest of World

 

 

82,500

 

 

 

82,500

 

Total milestone payments

 

$

426,250

 

 

$

831,250