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Basis of Presentation and Significant Accounting Policies - Schedule of Revenues consist of product sales to customers (Details) - USD ($)
$ in Thousands
 3 Months Ended 6 Months Ended
Jun. 30, 2023
Jun. 30, 2022
Jun. 30, 2023
Jun. 30, 2022
Disaggregation of Revenue [Line Items]        
Total revenues $ 165,235 $ 134,563 $ 283,697 $ 250,031
NUPLAZID        
Disaggregation of Revenue [Line Items]        
Total revenues 142,018 134,563 260,480 250,031
DAYBUE        
Disaggregation of Revenue [Line Items]        
Total revenues $ 23,217 $ 0 $ 23,217 $ 0