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Basis of Presentation and Significant Accounting Policies - Additional Information (Detail) - USD ($)
$ in Thousands
 1 Months Ended 3 Months Ended 6 Months Ended
Apr. 30, 2023
Jun. 30, 2023
Jun. 30, 2023
Jun. 30, 2022
Dec. 31, 2022
Other Commitments [Line Items]          
Impairment of intangible assets   $ 0 $ 0    
Intangible assets, net   68,219 68,219   $ 0
Amortization of intangible assets     1,364 $ 0  
License Agreements [Member]          
Other Commitments [Line Items]          
Intangible assets, net $ 40,000        
Finite-Lived Intangible Assets, Amortization Expense, Remainder of 2023   1,600 1,600    
Amortization of intangible assets     800    
Finite-Lived Intangible Assets, Amortization Expense, Subsequent year   3,100 3,100    
Neuren Pharmaceuticals Limited [Member] | License Agreements [Member]          
Other Commitments [Line Items]          
One-time contingent regulatory milestone payment pursuant to agreement with Neuren Group 40,000        
Intangible assets, net $ 29,600        
Finite-Lived Intangible Assets, Amortization Expense, Remainder of 2023   1,200 1,200    
Amortization of intangible assets     600    
Finite-Lived Intangible Assets, Amortization Expense, Subsequent year   $ 2,300 $ 2,300