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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($)
$ in Thousands
6 Months Ended
Jun. 30, 2023
Jun. 30, 2022
Cash flows from operating activities    
Net loss $ (41,907) $ (147,067)
Adjustments to reconcile net loss to net cash used in operating activities:    
Stock-based compensation 29,859 35,475
Amortization of premiums and accretion of discounts on investment securities (3,758) 547
Amortization of intangible assets 1,364 0
(Gain) loss on strategic investment (3,601) 158
Loss on sale of investment securities 505 0
Depreciation 828 1,031
Changes in operating assets and liabilities:    
Accounts receivable, net (19,657) (3,587)
Interest and other receivables (1,419) 42
Inventory (2,519) 1,465
Prepaid expenses (2,497) 2,940
Other assets (115) 0
Operating lease right-of-use assets 3,405 3,172
Accounts payable 6,065 4,978
Accrued liabilities 26,875 16,854
Operating lease liabilities (3,342) (3,972)
Long-term liabilities 182 (1,490)
Net cash used in operating activities (9,732) (89,454)
Cash flows from investing activities    
Purchases of investment securities (228,675) (125,377)
Sale and maturity of investment securities 266,910 200,925
Intangible assets (40,000) 0
Net cash (used in) provided by investing activities (1,765) 75,548
Cash flows from financing activities    
Proceeds from issuance of common stock, net of issuance costs 6,944 6,298
Net cash provided by financing activities 6,944 6,298
Effect of exchange rate changes on cash (2) 6
Net increase in cash, cash equivalents and restricted cash (4,555) (7,602)
Cash, cash equivalents and restricted cash    
Beginning of period 120,616 153,205
End of period 116,061 145,603
Supplemental disclosure of noncash information:    
Accrued milestone and contingent payments in connection with asset acquisition $ 29,583 $ 0