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Basis of Presentation and Significant Accounting Policies - Additional Information (Detail) - USD ($) $ in Thousands | 1 Months Ended | 3 Months Ended | 9 Months Ended |
--- | --- | --- | --- | ---
Apr. 30, 2023 | Sep. 30, 2023 | Sep. 30, 2023 | Sep. 30, 2022 | Dec. 31, 2022
Other Commitments [Line Items] |  |  |  |  |
Impairment of intangible assets |  | $ 0 | $ 0 |  |
Intangible assets, net |  | 66,855 | 66,855 |  | $ 0
Amortization of intangible assets |  |  | 2,728 | $ 0 |
License Agreements [Member] |  |  |  |  |
Other Commitments [Line Items] |  |  |  |  |
Intangible assets, net | $ 40,000 |  |  |  |
Finite-Lived Intangible Assets, Amortization Expense, Remainder of 2023 |  | 800 | 800 |  |
Amortization of intangible assets |  | 800 | 1,600 |  |
Finite-Lived Intangible Assets, Amortization Expense, Subsequent year |  | 3,100 | 3,100 |  |
Neuren Pharmaceuticals Limited [Member] | License Agreements [Member] |  |  |  |  |
Other Commitments [Line Items] |  |  |  |  |
One-time contingent regulatory milestone payment pursuant to agreement with Neuren Group | 40,000 |  |  |  |
Intangible assets, net | $ 29,600 |  |  |  |
Finite-Lived Intangible Assets, Amortization Expense, Remainder of 2023 |  | 600 | 600 |  |
Amortization of intangible assets |  | 600 | 1,200 |  |
Finite-Lived Intangible Assets, Amortization Expense, Subsequent year |  | $ 2,300 | $ 2,300 |  |

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- Definition The aggregate expense charged against earnings to allocate the cost of intangible assets (nonphysical assets not used in production) in a systematic and rational manner to the periods expected to benefit from such assets. As a noncash expense, this element is added back to net income when calculating cash provided by or used in operations using the indirect method. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Section 45 -Paragraph 28 -Subparagraph (b) -SubTopic 10 -Topic 230 -Publisher FASB -URI https://asc.fasb.org//1943274/2147482740/230-10-45-28 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 350 -SubTopic 30 -Section 45 -Paragraph 2 -Publisher FASB -URI https://asc.fasb.org//1943274/2147482686/350-30-45-2 Reference 3: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 350 -SubTopic 30 -Section 50 -Paragraph 2 -Subparagraph (a)(2) -Publisher FASB -URI https://asc.fasb.org//1943274/2147482665/350-30-50-2 + Details
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