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Condensed Consolidated Statements of Operations (Unaudited) - USD ($)
$ in Thousands
 3 Months Ended 9 Months Ended
Sep. 30, 2023
Sep. 30, 2022
Sep. 30, 2023
Sep. 30, 2022
Revenues        
Type of Revenue [Extensible List] us-gaap:ProductMember us-gaap:ProductMember us-gaap:ProductMember us-gaap:ProductMember
Total revenues $ 211,699 $ 130,714 $ 495,396 $ 380,745
Operating expenses        
Type of Cost, Good or Service [Extensible List] us-gaap:ProductMember us-gaap:ProductMember us-gaap:ProductMember us-gaap:ProductMember
Cost of product sales $ 14,622 $ 2,136 $ 23,747 $ 7,753
Research and development 156,963 81,336 284,878 285,837
Selling, general and administrative 97,890 78,108 295,094 264,688
Total operating expenses 269,475 161,580 603,719 558,278
Loss from operations (57,776) (30,866) (108,323) (177,533)
Interest income, net 4,125 2,295 12,475 2,980
Other income 1,508 2,156 5,109 1,999
Loss before income taxes (52,143) (26,415) (90,739) (172,554)
Income tax expense 13,033 768 16,344 1,696
Net loss $ (65,176) $ (27,183) $ (107,083) $ (174,250)
Net loss per common share, basic $ (0.4) $ (0.17) $ (0.65) $ (1.08)
Net loss per common share, diluted $ (0.4) $ (0.17) $ (0.65) $ (1.08)
Weighted average common shares outstanding, basic 164,234 161,852 163,488 161,580
Weighted average common shares outstanding, diluted 164,234 161,852 163,488 161,580