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Condensed Consolidated Statements of Cash Flows (Unaudited) - USD ($)
$ in Thousands
9 Months Ended
Sep. 30, 2023
Sep. 30, 2022
Cash flows from operating activities    
Net loss $ (107,083) $ (174,250)
Adjustments to reconcile net loss to net cash used in operating activities:    
Stock-based compensation 48,398 53,787
Amortization of premiums and accretion of discounts on investment securities (5,754) (642)
Amortization of intangible assets 2,728 0
Gain on strategic investment (5,109) (1,998)
Loss on sale of investment securities 524 0
Depreciation 1,187 1,537
Changes in operating assets and liabilities:    
Accounts receivable, net (30,607) 8,633
Interest and other receivables (845) 575
Inventory (13,741) 2,105
Prepaid expenses (16,552) 899
Other assets (32) 4,845
Operating lease right-of-use assets 5,029 (48)
Accounts payable (436) 3,132
Accrued liabilities 55,037 17,771
Operating lease liabilities (5,017) (5,959)
Long-term liabilities 3,586 (568)
Net cash used in operating activities (68,687) (90,181)
Cash flows from investing activities    
Purchases of investment securities (265,878) (269,626)
Sale and maturity of investment securities 326,020 360,615
Proceeds from sales of strategic investment 12,253 0
Purchases of property and equipment (50) 0
Intangible assets (40,000) 0
Net cash provided by investing activities 32,345 90,989
Cash flows from financing activities    
Proceeds from issuance of common stock, net of issuance costs 19,695 6,585
Net cash provided by financing activities 19,695 6,585
Effect of exchange rate changes on cash (6) 14
Net (decrease) increase in cash, cash equivalents and restricted cash (16,653) 7,407
Cash, cash equivalents and restricted cash    
Beginning of period 120,616 153,205
End of period 103,963 160,612
Supplemental disclosure of noncash information:    
Accrued milestone and contingent payments in connection with asset acquisition $ 29,583 $ 0