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Income Taxes - Components of Deferred Tax Assets (Detail) - USD ($) $ in Thousands | Dec. 31, 2023 | Dec. 31, 2022
--- | --- | ---
Deferred tax assets |  |
NOL carryforwards | $ 149,049 | $ 225,993
R&D credit carryforwards | 70,906 | 83,074
Capitalized R&D | 90,164 | 38,507
Stock-based compensation | 51,028 | 51,661
Charitable contributions | 40,956 | 42,677
Lease liabilities | 13,671 | 14,730
Intangibles | 43,220 | 24,030
Property and equipment | 51 | 0
Accrued rebates | 19,401 | 5,748
Other | 16,036 | 8,022
Total deferred tax assets | 494,482 | 494,442
Valuation allowance | (482,089) | (481,210)
Deferred tax liabilities |  |
Propery and equipment | 0 | (29)
Right-of-use assets | (12,393) | (13,203)
Total deferred tax liabilities | (12,393) | (13,232)
Total net deferred tax assets | $ 0 | $ 0

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