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Summary of Significant Accounting Policies - Schedule of Revenues consist of product sales to customers (Details) - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2023
Dec. 31, 2022
Dec. 31, 2021
Disaggregation of Revenue [Line Items]      
Product sales, net $ 726,437 $ 517,235 $ 484,145
NUPLAZID      
Disaggregation of Revenue [Line Items]      
Product sales, net 549,248 517,235 484,145
DAYBUE      
Disaggregation of Revenue [Line Items]      
Product sales, net $ 177,189 $ 0 $ 0