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v3.25.0.1

Consolidated Statements of Cash Flows - USD ($) $ in Thousands | 12 Months Ended
--- | ---
Dec. 31, 2024 | Dec. 31, 2023 | Dec. 31, 2022
Cash flows from operating activities |  |  |
Net income (loss) | $ 226,451 | $ (61,286) | $ (215,975)
Adjustments to reconcile net income (loss) to net cash provided by (used in) operating activities: |  |  |
Stock-based compensation | 67,049 | 66,421 | 68,201
Amortization of premiums and accretion of discounts on investment securities | (9,304) | (7,533) | (2,736)
Amortization of intangible assets | 14,963 | 4,093 | 0
Gain on sale of non-financial asset | (146,515) | 0 | 0
Gain on strategic investment | 0 | (5,109) | (3,542)
Depreciation | 920 | 1,459 | 2,026
Loss on sale of investment securities | 0 | 524 | 0
Changes in operating assets and liabilities: |  |  |
Accounts receivable, net | (472) | (36,072) | 2,171
Interest and other receivables | (1,873) | (3,198) | 93
Inventory | (49,550) | (28,808) | 2,415
Prepaid expenses and other current assets | (16,590) | (17,693) | 2,494
Operating lease right-of-use assets | 7,502 | 5,769 | 6,566
Other assets | 117 | (33) | (48)
Accounts payable | (1,351) | 4,797 | 5,870
Accrued liabilities | 71,061 | 93,170 | 24,306
Operating lease liabilities | (7,598) | (5,872) | (7,916)
Long-term liabilities | 2,909 | 6,073 | 2,040
Net cash provided by (used in) operating activities | 157,719 | 16,702 | (114,035)
Cash flows from investing activities |  |  |
Purchases of investment securities | (505,095) | (369,985) | (363,174)
Sale and maturity of investment securities | 328,565 | 429,780 | 436,415
Proceeds from sale of non-financial asset | 146,515 | 0 | 0
Proceeds from sales of strategic investment | 0 | 12,253 | 0
Net purchases of property and equipment | (523) | (50) | 0
Intangible assets | 0 | (40,000) | 0
Net cash (used in) provided by investing activities | (30,538) | 31,998 | 73,241
Cash flows from financing activities |  |  |
Proceeds from issuance of common stock, net of issuance costs | 6,845 | 25,129 | 8,199
Net cash provided by financing activities | 6,845 | 25,129 | 8,199
Effect of exchange rate changes on cash | (94) | (18) | 6
Net increase (decrease) in cash, cash equivalents and restricted cash | 133,932 | 73,811 | (32,589)
Cash, cash equivalents and restricted cash |  |  |
Beginning of period | 194,427 | 120,616 | 153,205
End of period | 328,359 | 194,427 | 120,616
Supplemental disclosure of cash flow information: |  |  |
Cash paid for income taxes | 19,521 | 5,850 | 2,190
Supplemental disclosure of noncash information: |  |  |
Accrued inventory purchases | 1,268 | 0 | 0
Accrued milestone and contingent payments in connection with asset acquisition | $ 98,838 | $ 29,583 | $ 0

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