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Segment Reporting (Tables) | 12 Months Ended
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Dec. 31, 2024
Segment Reporting [Abstract] |
Schedule of Segment Revenue, Segment Profit and Segment Expenses | The following table illustrates reported segment revenue, segment profit and significant segment expenses (in thousands):
|  | Year Ended December 31, |
|  | 2024 |  |  | 2023 |  |  | 2022 |
NUPLAZID net revenue |  | $ | 609,385 |  |  | $ | 549,248 |  |  | $ | 517,235 |
DAYBUE net revenue |  |  | 348,412 |  |  |  | 177,189 |  |  |  | — |
Total revenues |  |  | 957,797 |  |  |  | 726,437 |  |  |  | 517,235 |
Less: |  |  |  |  |  |  |  |  |
Cost of goods sold |  |  | 30,068 |  |  |  | 19,826 |  |  |  | 10,166 |
License fees and royalties |  |  | 51,773 |  |  |  | 21,812 |  |  |  | — |
Research and development expense: |  |  |  |  |  |  |  |  |
External research and development |  |  | 194,539 |  |  |  | 170,036 |  |  |  | 189,832 |
Internal costs(1) |  |  | 74,210 |  |  |  | 79,083 |  |  |  | 83,002 |
Upfront and milestone payments |  |  | 34,500 |  |  |  | 102,500 |  |  |  | 88,741 |
Total research and development expense |  |  | 303,249 |  |  |  | 351,619 |  |  |  | 361,575 |
Selling, general and administrative |  |  | 488,428 |  |  |  | 406,559 |  |  |  | 369,090 |
Gain on sale of non-financial asset |  |  | (146,515 | ) |  |  | — |  |  |  | — |
Interest income, net |  |  | (25,458 | ) |  |  | (17,234 | ) |  |  | (6,610 | )
Other income |  |  | (1,823 | ) |  |  | (5,109 | ) |  |  | (3,542 | )
Income tax expense |  |  | 31,624 |  |  |  | 10,250 |  |  |  | 2,531 |
Consolidated net income |  | $ | 226,451 |  |  | $ | (61,286 | ) |  | $ | (215,975 | )
(1) Includes personnel expenses and costs allocated to multiple research and development programs, including benefits, information technology, facilities and inventory.

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- Definition Tabular disclosure of all significant reconciling items in the reconciliation of total revenues from reportable segments to the entity's consolidated revenues. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 31 -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-31 Reference 2: http://fasb.org/us-gaap/role/ref/legacyRef -Name Accounting Standards Codification -Topic 280 -SubTopic 10 -Section 50 -Paragraph 30 -Subparagraph (a) -Publisher FASB -URI https://asc.fasb.org/1943274/2147482810/280-10-50-30 + Details
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