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Consolidated Statements of Operations - USD ($)
shares in Thousands, $ in Thousands
 12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
Revenues      
Type of Revenue [Extensible List] us-gaap:ProductMember us-gaap:ProductMember us-gaap:ProductMember
Total revenues $ 957,797 $ 726,437 $ 517,235
Operating expenses      
Type of Cost, Good or Service [Extensible List] us-gaap:ProductMember us-gaap:ProductMember us-gaap:ProductMember
Cost of product sales $ 81,841 $ 41,638 $ 10,166
Research and development 303,249 351,619 361,575
Selling, general and administrative 488,428 406,559 369,090
Gain on sale of non-financial asset (146,515) 0 0
Total operating expenses 727,003 799,816 740,831
Income (loss) from operations 230,794 (73,379) (223,596)
Interest income, net 25,458 17,234 6,610
Other income 1,823 5,109 3,542
Income (loss) before income taxes 258,075 (51,036) (213,444)
Income tax expense 31,624 10,250 2,531
Net income (loss) $ 226,451 $ (61,286) $ (215,975)
Earnings (net loss) per share, Basic $ 1.37 $ (0.37) $ (1.34)
Earnings (net loss) per share, diluted $ 1.36 $ (0.37) $ (1.34)
Weighted average common shares outstanding, basic 165,717 163,819 161,683
Weighted average common shares outstanding, diluted 166,362 163,819 161,683