XML 94 R74.htm IDEA: XBRL DOCUMENT v3.25.0.1
Segment Reporting - Schedule of Segment Revenue, Segment Profit and Segment Expenses (Details) - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
Segment Reporting Information [Line Items]      
Total revenues $ 957,797 $ 726,437 $ 517,235
Cost of goods sold 81,841 41,638 10,166
Research and development expense 303,249 351,619 361,575
Selling, general and administrative 488,428 406,559 369,090
Gain on sale of non-financial asset (146,515) 0 0
Interest income, net (25,458) (17,234) (6,610)
Other income (1,823) (5,109) (3,542)
Income tax expense 31,624 10,250 2,531
Net income (loss) 226,451 (61,286) (215,975)
Reportable Segment [Member]      
Segment Reporting Information [Line Items]      
Total revenues 957,797 726,437 517,235
Cost of goods sold 30,068 19,826 10,166
License fees and royalties 51,773 21,812 0
Research and development expense 303,249 351,619 361,575
Selling, general and administrative 488,428 406,559 369,090
Gain on sale of non-financial asset (146,515) 0 0
Interest income, net (25,458) (17,234) (6,610)
Other income (1,823) (5,109) (3,542)
Income tax expense 31,624 10,250 2,531
Net income (loss) 226,451 (61,286) (215,975)
Reportable Segment [Member] | External research and development      
Segment Reporting Information [Line Items]      
Research and development expense 194,539 170,036 189,832
Reportable Segment [Member] | Internal costs      
Segment Reporting Information [Line Items]      
Research and development expense [1] 74,210 79,083 83,002
Reportable Segment [Member] | Upfront and Milestone Payments      
Segment Reporting Information [Line Items]      
Research and development expense 34,500 102,500 88,741
NUPLAZID | Reportable Segment [Member]      
Segment Reporting Information [Line Items]      
Total revenues 609,385 549,248 517,235
DAYBUE | Reportable Segment [Member]      
Segment Reporting Information [Line Items]      
Total revenues $ 348,412 $ 177,189 $ 0
[1] Includes personnel expenses and costs allocated to multiple research and development programs, including benefits, information technology, facilities and inventory.