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Segment Reporting - Schedule of Segment Revenue, Segment Profit and Segment Expenses (Details) - USD ($)
$ in Thousands
 3 Months Ended 6 Months Ended
Jun. 30, 2025
Jun. 30, 2024
Jun. 30, 2025
Jun. 30, 2024
Segment Reporting Information [Line Items]        
Total revenues $ 264,566 $ 241,963 $ 508,882 $ 447,794
Cost of goods sold 20,734 18,230 41,126 41,181
Research and development 77,951 76,233 156,216 135,912
Selling, general and administrative 133,507 117,063 259,877 225,054
Interest income, net 7,243 6,359 15,144 11,865
Other income 594 386 1,183 672
Income tax expense 13,545 3,793 22,337 8,240
Net Income (Loss) 26,666 33,389 45,653 49,944
Reportable Segment [Member]        
Segment Reporting Information [Line Items]        
Total revenues 264,566 241,963 508,882 447,794
Cost of goods sold 8,384 7,430 17,595 17,504
License fees and royalties 12,350 10,800 23,531 23,677
Research and development 77,951 76,233 156,216 135,912
Selling, general and administrative 133,507 117,063 259,877 225,054
Interest income, net (7,243) (6,359) (15,144) (11,865)
Other income (594) (386) (1,183) (672)
Income tax expense 13,545 3,793 22,337 8,240
Net Income (Loss) 26,666 33,389 45,653 49,944
Reportable Segment [Member] | External research and development        
Segment Reporting Information [Line Items]        
Research and development 54,319 57,381 109,304 98,870
Reportable Segment [Member] | Internal costs        
Segment Reporting Information [Line Items]        
Research and development [1] 23,632 18,852 46,912 37,042
NUPLAZID | Reportable Segment [Member]        
Segment Reporting Information [Line Items]        
Total revenues 168,479 157,409 328,199 287,332
DAYBUE | Reportable Segment [Member]        
Segment Reporting Information [Line Items]        
Total revenues $ 96,087 $ 84,554 $ 180,683 $ 160,462
[1] Includes personnel expenses and costs allocated to multiple research and development programs, including benefits, information technology, facilities and inventory.