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Basis of Presentation and Significant Accounting Policies - Additional Information (Detail) $ in Thousands | 3 Months Ended | 9 Months Ended |
--- | --- | --- | ---
Sep. 30, 2025 USD ($) | Sep. 30, 2024 USD ($) | Sep. 30, 2025 USD ($) Segment | Sep. 30, 2024 USD ($) | Dec. 31, 2024 USD ($)
Other Commitments [Line Items] |  |  |  |  |
Impairment of intangible assets | $ 0 | $ 0 | $ 0 | $ 0 |
Intangible assets, net | 111,615 |  | 111,615 |  | $ 119,782
Amortization of intangible assets |  |  | $ 8,167 | 9,975 |
Number of operating segements | Segment |  |  | 1 |  |
Neuren Pharmaceuticals Limited [Member] | License Agreements [Member] |  |  |  |  |
Other Commitments [Line Items] |  |  |  |  |
Finite-Lived Intangible Assets, Amortization Expense, Remainder of 2024 | 2,700 |  | $ 2,700 |  |
Amortization of intangible assets | 2,700 | $ 2,300 | 8,200 | $ 10,000 |
Finite-Lived Intangible Assets, Amortization Expense, Subsequent year | 10,900 |  | 10,900 |  |
FDA approval, Sales of DAYBUE and Sale of PRV [Member] | Neuren Pharmaceuticals Limited [Member] | License Agreements [Member] |  |  |  |  |
Other Commitments [Line Items] |  |  |  |  |
Intangible assets, net | $ 138,800 |  | $ 138,800 |  |

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