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Segment Reporting - Schedule of Segment Revenue, Segment Profit and Segment Expenses (Details) - USD ($)
$ in Thousands
 3 Months Ended 9 Months Ended
Sep. 30, 2025
Sep. 30, 2024
Sep. 30, 2025
Sep. 30, 2024
Segment Reporting Information [Line Items]        
Total revenues $ 278,633 $ 250,401 $ 787,516 $ 698,195
Cost of goods sold 21,647 18,857 62,773 60,038
Research and development 87,829 66,606 244,045 202,518
Selling, general and administrative 133,401 133,294 393,278 358,348
Interest income, net 8,246 6,586 23,390 18,451
Other income 593 576 1,775 1,248
Income tax expense (benefit) (27,184) 6,041 (4,847) 14,281
Net Income (Loss) 71,779 32,765 117,432 82,709
Reportable Segment [Member]        
Segment Reporting Information [Line Items]        
Total revenues 278,633 250,401 787,516 698,195
Cost of goods sold 8,041 7,357 25,636 24,861
License fees and royalties 13,606 11,500 37,137 35,177
Research and development 87,829 66,606 244,045 202,518
Selling, general and administrative 133,401 133,294 393,278 358,348
Interest income, net (8,246) (6,586) (23,390) (18,451)
Other income (593) (576) (1,775) (1,248)
Income tax expense (benefit) (27,184) 6,041 (4,847) 14,281
Net Income (Loss) 71,779 32,765 117,432 82,709
Reportable Segment [Member] | External research and development        
Segment Reporting Information [Line Items]        
Research and development 60,153 48,137 169,457 141,007
Reportable Segment [Member] | Internal costs        
Segment Reporting Information [Line Items]        
Research and development [1] 24,676 17,969 71,588 55,011
Reportable Segment [Member] | Upfront And Milestone Payments        
Segment Reporting Information [Line Items]        
Research and development 3,000 500 3,000 6,500
NUPLAZID | Reportable Segment [Member]        
Segment Reporting Information [Line Items]        
Total revenues 177,530 159,186 505,730 446,518
DAYBUE | Reportable Segment [Member]        
Segment Reporting Information [Line Items]        
Total revenues $ 101,103 $ 91,215 $ 281,786 $ 251,677
[1] Includes personnel expenses and costs allocated to multiple research and development programs, including benefits, information technology, facilities and inventory.