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7. STOCKHOLDERS' EQUITY (Tables)

9 Months Ended

Sep. 30, 2019

STOCKHOLDERS' EQUITY

Schedule of assumptions

		Nine Months Ended September 30,
		2019				2018
Expected term			5.8 - 6.3 years				5.8-6.3 years
Volatility			54.2-62.9%				54-57%
Dividend yield			0.0				0.0
Risk-free interest rate			1.36-2.92%				2.40-2.97%

Schedule of stock option activity

		Shares				Weighted Average Exercise Price
Balance at December 31, 2018			4,342,231			$	5.16
Forfeited			(152,903	)		$	3.94
Expired			(12,985	)		$	4.88
Granted			1,493,100			$	3.49
Exercised			(29,904	)		$	2.84
Balance at September 30, 2019			5,639,539			$	4.76
Options exercisable			3,036,543			$	5.67

Stock-based compensation expense

		Three Months Ended September 30,								Nine Months Ended September 30,
		2019				2018				2019				2018
Research and development		$	95,757			$	84,588			$	271,823			$	246,231
Plasma centers			13,333				7,836				38,086				22,682
Selling, general and administrative			491,710				444,651				1,559,530				1,245,702
Cost of product revenue			49,870				40,506				145,230				113,141
Total stock-based compensation expense		$	650,670			$	577,581			$	2,014,669			$	1,627,756

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