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STOCKHOLDERS EQUITY (Details 3) - USD ($) | 3 Months Ended | 6 Months Ended
--- | --- | ---
Jun. 30, 2020 | Jun. 30, 2019 | Jun. 30, 2020 | Jun. 30, 2019
Stock-based compensation | $ 715,608 | $ 726,736 | $ 1,392,156 | $ 1,363,999
Research and development [Member] |  |  |  |
Stock-based compensation | 105,029 | 89,543 | 15,754 | 176,066
Plasma centers [Member] |  |  |  |
Stock-based compensation | 8,510 | 13,213 | 15,754 | 24,753
Selling, general and administrative [Member] |  |  |  |
Stock-based compensation | 539,256 | 569,349 | 1,063,145 | 1,067,820
Cost of product revenue [Member] |  |  |  |
Stock-based compensation | $ 62,813 | $ 54,631 | $ 114,654 | $ 95,360

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