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STOCKHOLDERS EQUITY (Tables) | 6 Months Ended
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Jun. 30, 2021
STOCKHOLDERS' EQUITY [Abstract] |
Schedule of Assumptions | The following assumptions were used to determine the fair value of options granted during the six months ended June 30, 2021 and 2020:
| Six Months Ended June 30,
| 2021 |  | 2020
Expected term | 5.5 - 6.3 years |  | 5.5 - 6.3 years
Volatility | 69% |  | 62-67%
Dividend yield | 0.0 |  | 0.0
Risk-free interest rate | 0.80-1.14% |  | 0.38-1.68%
Schedule of Option Activity | A summary of the Company’s option activity under the 2007 Plan and 2014 Plan and related information is as follows:
|  | Shares |  |  | Weighted Average Exercise Price |
Options outstanding, vested and expected to vest at December 31, 2020 |  |  | 6,922,931 |  |  | $ | 4.40 |
Forfeited |  |  | (404,782 | ) |  | $ | 2.96 |
Expired |  |  | (393,170 | ) |  | $ | 5.03 |
Granted |  |  | 1,658,050 |  |  | $ | 2.26 |
Exercised |  |  | - |  |  | $ | - |
Options outstanding, vested and expected to vest at June 30, 2021 |  |  | 7,783,029 |  |  | $ | 3.98 |
Options exercisable |  |  | 5,011,506 |  |  | $ | 4.70 |
Schedule of Unvested RSU Activity | A summary of the Company’s unvested RSU activity and related information is as follows:
|  | Shares |  |  | Weighted Average Grant Date Fair Value |
Balance at December 31, 2020 |  |  | 326,000 |  |  | $ | 2.81 |
Granted |  |  | 542,244 |  |  | $ | 2.29 |
Vested |  |  | (87,750 | ) |  | $ | 2.81 |
Forfeited |  |  | (94,361 | ) |  | $ | 2.53 |
Balance at June 30, 2021 |  |  | 686,133 |  |  | $ | 2.44 |
Schedule of Stock-Based Compensation Expense | Total stock-based compensation expense for all awards granted under the Company’s equity incentive plans for the three months and six months June 30, 2021 and 2020 is as follows:
|  | Three Months Ended June 30, |  |  | Six Months Ended June 30, |
|  | 2021 |  |  | 2020 |  |  | 2021 |  |  | 2020 |
Research and development |  | $ | 42,479 |  |  | $ | 105,029 |  |  | $ | 147,706 |  |  | $ | 198,603 |
Plasma center operating expenses |  |  | 13,637 |  |  |  | 8,510 |  |  |  | 24,455 |  |  |  | 15,754 |
Selling, general and administrative |  |  | 665,836 |  |  |  | 539,256 |  |  |  | 1,254,327 |  |  |  | 1,063,145 |
Cost of product revenue |  |  | 83,237 |  |  |  | 62,813 |  |  |  | 160,098 |  |  |  | 114,654 |
Total stock-based compensation expense |  | $ | 805,189 |  |  | $ | 715,608 |  |  | $ | 1,586,586 |  |  | $ | 1,392,156 |

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- Definition Tabular disclosure of the significant assumptions used during the year to estimate the fair value of stock options, including, but not limited to: (a) expected term of share options and similar instruments, (b) expected volatility of the entity's shares, (c) expected dividends, (d) risk-free rate(s), and (e) discount for post-vesting restrictions. + References Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef -Publisher FASB -Name Accounting Standards Codification -Topic 718 -SubTopic 10 -Section 50 -Paragraph 2 -Subparagraph (f)(2) -URI http://asc.fasb.org/extlink&oid=120381028&loc=d3e5070-113901 + Details
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