<?xml version="1.0" encoding="US-ASCII"?>
<!--XBRL Document Created with Wdesk from Workiva-->
<!-- -->
<link:linkbase xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd" xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance">
  <link:roleRef roleURI="http://www.renasantbank.com/role/AllowanceForLoanLosses" xlink:href="rnst-20170630.xsd#AllowanceForLoanLosses" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/AllowanceForLoanLossesDetails" xlink:href="rnst-20170630.xsd#AllowanceForLoanLossesDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/AllowanceForLoanLossesDetails1" xlink:href="rnst-20170630.xsd#AllowanceForLoanLossesDetails1" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/AllowanceForLoanLossesDetails2" xlink:href="rnst-20170630.xsd#AllowanceForLoanLossesDetails2" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/AllowanceForLoanLossesTables" xlink:href="rnst-20170630.xsd#AllowanceForLoanLossesTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/CondensedConsolidatedStatementsOfCashFlowsUnaudited" xlink:href="rnst-20170630.xsd#CondensedConsolidatedStatementsOfCashFlowsUnaudited" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/ConsolidatedBalanceSheets" xlink:href="rnst-20170630.xsd#ConsolidatedBalanceSheets" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/ConsolidatedBalanceSheetsParenthetical" xlink:href="rnst-20170630.xsd#ConsolidatedBalanceSheetsParenthetical" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/ConsolidatedStatementsOfComprehensiveIncomeUnaudited" xlink:href="rnst-20170630.xsd#ConsolidatedStatementsOfComprehensiveIncomeUnaudited" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/ConsolidatedStatementsOfIncomeUnaudited" xlink:href="rnst-20170630.xsd#ConsolidatedStatementsOfIncomeUnaudited" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/DerivativeInstruments" xlink:href="rnst-20170630.xsd#DerivativeInstruments" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/DerivativeInstrumentsDetails" xlink:href="rnst-20170630.xsd#DerivativeInstrumentsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/DerivativeInstrumentsDetails1" xlink:href="rnst-20170630.xsd#DerivativeInstrumentsDetails1" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/DerivativeInstrumentsDetails2" xlink:href="rnst-20170630.xsd#DerivativeInstrumentsDetails2" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/DerivativeInstrumentsDetailsTextual" xlink:href="rnst-20170630.xsd#DerivativeInstrumentsDetailsTextual" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/DerivativeInstrumentsTables" xlink:href="rnst-20170630.xsd#DerivativeInstrumentsTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/DocumentAndEntityInformation" xlink:href="rnst-20170630.xsd#DocumentAndEntityInformation" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/EmployeeBenefitAndDeferredCompensationPlans" xlink:href="rnst-20170630.xsd#EmployeeBenefitAndDeferredCompensationPlans" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/EmployeeBenefitAndDeferredCompensationPlansDetails1" xlink:href="rnst-20170630.xsd#EmployeeBenefitAndDeferredCompensationPlansDetails1" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/EmployeeBenefitAndDeferredCompensationPlansDetails2" xlink:href="rnst-20170630.xsd#EmployeeBenefitAndDeferredCompensationPlansDetails2" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/EmployeeBenefitAndDeferredCompensationPlansDetails3" xlink:href="rnst-20170630.xsd#EmployeeBenefitAndDeferredCompensationPlansDetails3" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/EmployeeBenefitAndDeferredCompensationPlansDetailsTextual" xlink:href="rnst-20170630.xsd#EmployeeBenefitAndDeferredCompensationPlansDetailsTextual" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/EmployeeBenefitAndDeferredCompensationPlansTables" xlink:href="rnst-20170630.xsd#EmployeeBenefitAndDeferredCompensationPlansTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/FairValueMeasurements" xlink:href="rnst-20170630.xsd#FairValueMeasurements" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/FairValueMeasurementsDetails" xlink:href="rnst-20170630.xsd#FairValueMeasurementsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/FairValueMeasurementsDetails1" xlink:href="rnst-20170630.xsd#FairValueMeasurementsDetails1" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/FairValueMeasurementsDetails2" xlink:href="rnst-20170630.xsd#FairValueMeasurementsDetails2" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/FairValueMeasurementsDetails3" xlink:href="rnst-20170630.xsd#FairValueMeasurementsDetails3" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/FairValueMeasurementsDetails4" xlink:href="rnst-20170630.xsd#FairValueMeasurementsDetails4" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/FairValueMeasurementsDetails5" xlink:href="rnst-20170630.xsd#FairValueMeasurementsDetails5" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/FairValueMeasurementsDetails6" xlink:href="rnst-20170630.xsd#FairValueMeasurementsDetails6" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/FairValueMeasurementsDetails7" xlink:href="rnst-20170630.xsd#FairValueMeasurementsDetails7" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/FairValueMeasurementsDetailsTextual" xlink:href="rnst-20170630.xsd#FairValueMeasurementsDetailsTextual" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/FairValueMeasurementsTables" xlink:href="rnst-20170630.xsd#FairValueMeasurementsTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/GoodwillAndOtherIntangibleAssets" xlink:href="rnst-20170630.xsd#GoodwillAndOtherIntangibleAssets" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/GoodwillAndOtherIntangibleAssetsDetails" xlink:href="rnst-20170630.xsd#GoodwillAndOtherIntangibleAssetsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/GoodwillAndOtherIntangibleAssetsDetails1" xlink:href="rnst-20170630.xsd#GoodwillAndOtherIntangibleAssetsDetails1" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/GoodwillAndOtherIntangibleAssetsDetails2" xlink:href="rnst-20170630.xsd#GoodwillAndOtherIntangibleAssetsDetails2" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/GoodwillAndOtherIntangibleAssetsDetails3" xlink:href="rnst-20170630.xsd#GoodwillAndOtherIntangibleAssetsDetails3" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/GoodwillAndOtherIntangibleAssetsTables" xlink:href="rnst-20170630.xsd#GoodwillAndOtherIntangibleAssetsTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/IncomeTaxes" xlink:href="rnst-20170630.xsd#IncomeTaxes" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/IncomeTaxesDetails" xlink:href="rnst-20170630.xsd#IncomeTaxesDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/IncomeTaxesDetailsTextual" xlink:href="rnst-20170630.xsd#IncomeTaxesDetailsTextual" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/IncomeTaxesTables" xlink:href="rnst-20170630.xsd#IncomeTaxesTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/InvestmentsInQualifiedAffordableHousingProjects" xlink:href="rnst-20170630.xsd#InvestmentsInQualifiedAffordableHousingProjects" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/InvestmentsInQualifiedAffordableHousingProjectsDetails" xlink:href="rnst-20170630.xsd#InvestmentsInQualifiedAffordableHousingProjectsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/InvestmentsInQualifiedAffordableHousingProjectsTables" xlink:href="rnst-20170630.xsd#InvestmentsInQualifiedAffordableHousingProjectsTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/MergersAndAcquisitions" xlink:href="rnst-20170630.xsd#MergersAndAcquisitions" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/MergersAndAcquisitionsDetailsTextual" xlink:href="rnst-20170630.xsd#MergersAndAcquisitionsDetailsTextual" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/MortgageServicingRights" xlink:href="rnst-20170630.xsd#MortgageServicingRights" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/MortgageServicingRightsDetails" xlink:href="rnst-20170630.xsd#MortgageServicingRightsDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/MortgageServicingRightsDetails1" xlink:href="rnst-20170630.xsd#MortgageServicingRightsDetails1" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/MortgageServicingRightsDetailsTextual" xlink:href="rnst-20170630.xsd#MortgageServicingRightsDetailsTextual" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/MortgageServicingRightsTables" xlink:href="rnst-20170630.xsd#MortgageServicingRightsTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/NetIncomePerCommonShare" xlink:href="rnst-20170630.xsd#NetIncomePerCommonShare" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/NetIncomePerCommonShareDetails" xlink:href="rnst-20170630.xsd#NetIncomePerCommonShareDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/NetIncomePerCommonShareDetails1" xlink:href="rnst-20170630.xsd#NetIncomePerCommonShareDetails1" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/NetIncomePerCommonShareTables" xlink:href="rnst-20170630.xsd#NetIncomePerCommonShareTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/NonPurchasedLoans" xlink:href="rnst-20170630.xsd#NonPurchasedLoans" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/NonPurchasedLoansDetails" xlink:href="rnst-20170630.xsd#NonPurchasedLoansDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/NonPurchasedLoansDetails1" xlink:href="rnst-20170630.xsd#NonPurchasedLoansDetails1" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/NonPurchasedLoansDetails2" xlink:href="rnst-20170630.xsd#NonPurchasedLoansDetails2" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/NonPurchasedLoansDetails3" xlink:href="rnst-20170630.xsd#NonPurchasedLoansDetails3" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/NonPurchasedLoansDetails4" xlink:href="rnst-20170630.xsd#NonPurchasedLoansDetails4" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/NonPurchasedLoansDetails5" xlink:href="rnst-20170630.xsd#NonPurchasedLoansDetails5" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/NonPurchasedLoansDetails6" xlink:href="rnst-20170630.xsd#NonPurchasedLoansDetails6" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/NonPurchasedLoansDetails7" xlink:href="rnst-20170630.xsd#NonPurchasedLoansDetails7" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/NonPurchasedLoansDetailsTextual" xlink:href="rnst-20170630.xsd#NonPurchasedLoansDetailsTextual" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/NonPurchasedLoansTables" xlink:href="rnst-20170630.xsd#NonPurchasedLoansTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/OtherComprehensiveIncomeLoss" xlink:href="rnst-20170630.xsd#OtherComprehensiveIncomeLoss" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/OtherComprehensiveIncomeLossDetails" xlink:href="rnst-20170630.xsd#OtherComprehensiveIncomeLossDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/OtherComprehensiveIncomeLossDetails1" xlink:href="rnst-20170630.xsd#OtherComprehensiveIncomeLossDetails1" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/OtherComprehensiveIncomeLossTables" xlink:href="rnst-20170630.xsd#OtherComprehensiveIncomeLossTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/OtherRealEstateOwned" xlink:href="rnst-20170630.xsd#OtherRealEstateOwned" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/OtherRealEstateOwnedDetails" xlink:href="rnst-20170630.xsd#OtherRealEstateOwnedDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/OtherRealEstateOwnedDetails1" xlink:href="rnst-20170630.xsd#OtherRealEstateOwnedDetails1" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/OtherRealEstateOwnedDetails2" xlink:href="rnst-20170630.xsd#OtherRealEstateOwnedDetails2" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/OtherRealEstateOwnedDetailsTextual" xlink:href="rnst-20170630.xsd#OtherRealEstateOwnedDetailsTextual" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/OtherRealEstateOwnedTables" xlink:href="rnst-20170630.xsd#OtherRealEstateOwnedTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/PurchasedLoans" xlink:href="rnst-20170630.xsd#PurchasedLoans" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/PurchasedLoansDetails" xlink:href="rnst-20170630.xsd#PurchasedLoansDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/PurchasedLoansDetails1" xlink:href="rnst-20170630.xsd#PurchasedLoansDetails1" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/PurchasedLoansDetails10" xlink:href="rnst-20170630.xsd#PurchasedLoansDetails10" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/PurchasedLoansDetails2" xlink:href="rnst-20170630.xsd#PurchasedLoansDetails2" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/PurchasedLoansDetails3" xlink:href="rnst-20170630.xsd#PurchasedLoansDetails3" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/PurchasedLoansDetails4" xlink:href="rnst-20170630.xsd#PurchasedLoansDetails4" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/PurchasedLoansDetails5" xlink:href="rnst-20170630.xsd#PurchasedLoansDetails5" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/PurchasedLoansDetails6" xlink:href="rnst-20170630.xsd#PurchasedLoansDetails6" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/PurchasedLoansDetails7" xlink:href="rnst-20170630.xsd#PurchasedLoansDetails7" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/PurchasedLoansDetails8" xlink:href="rnst-20170630.xsd#PurchasedLoansDetails8" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/PurchasedLoansDetails9" xlink:href="rnst-20170630.xsd#PurchasedLoansDetails9" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/PurchasedLoansDetailsTextual" xlink:href="rnst-20170630.xsd#PurchasedLoansDetailsTextual" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/PurchasedLoansTables" xlink:href="rnst-20170630.xsd#PurchasedLoansTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/RedemptionOfLongTermDebt" xlink:href="rnst-20170630.xsd#RedemptionOfLongTermDebt" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/RedemptionOfLongTermDebtDetails" xlink:href="rnst-20170630.xsd#RedemptionOfLongTermDebtDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/RegulatoryMatters" xlink:href="rnst-20170630.xsd#RegulatoryMatters" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/RegulatoryMattersDetails" xlink:href="rnst-20170630.xsd#RegulatoryMattersDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/RegulatoryMattersDetails1" xlink:href="rnst-20170630.xsd#RegulatoryMattersDetails1" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/RegulatoryMattersTables" xlink:href="rnst-20170630.xsd#RegulatoryMattersTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/Securities" xlink:href="rnst-20170630.xsd#Securities" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/SecuritiesDetails" xlink:href="rnst-20170630.xsd#SecuritiesDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/SecuritiesDetails1" xlink:href="rnst-20170630.xsd#SecuritiesDetails1" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/SecuritiesDetails2" xlink:href="rnst-20170630.xsd#SecuritiesDetails2" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/SecuritiesDetails3" xlink:href="rnst-20170630.xsd#SecuritiesDetails3" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/SecuritiesDetails4" xlink:href="rnst-20170630.xsd#SecuritiesDetails4" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/SecuritiesDetails5" xlink:href="rnst-20170630.xsd#SecuritiesDetails5" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/SecuritiesDetails6" xlink:href="rnst-20170630.xsd#SecuritiesDetails6" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/SecuritiesDetailsTextual" xlink:href="rnst-20170630.xsd#SecuritiesDetailsTextual" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/SecuritiesTables" xlink:href="rnst-20170630.xsd#SecuritiesTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/SegmentReporting" xlink:href="rnst-20170630.xsd#SegmentReporting" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/SegmentReportingDetails" xlink:href="rnst-20170630.xsd#SegmentReportingDetails" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/SegmentReportingTables" xlink:href="rnst-20170630.xsd#SegmentReportingTables" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/SummaryOfSignificantAccountingPolicies" xlink:href="rnst-20170630.xsd#SummaryOfSignificantAccountingPolicies" xlink:type="simple" />
  <link:roleRef roleURI="http://www.renasantbank.com/role/SummaryOfSignificantAccountingPoliciesPolicies" xlink:href="rnst-20170630.xsd#SummaryOfSignificantAccountingPoliciesPolicies" xlink:type="simple" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/AllowanceForLoanLosses" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/AllowanceForLoanLossesDetails" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/AllowanceForLoanLossesDetails1" xlink:type="extended">
    <link:loc xlink:href="rnst-20170630.xsd#rnst_FinancingReceivableAllowanceforCreditLossesNetRecoveriesWritedowns" xlink:label="loc_rnst_FinancingReceivableAllowanceforCreditLossesNetRecoveriesWritedowns_aea21527-5355-6f03-8f6e-a767ae694cfe" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FinancingReceivableAllowanceForCreditLossesWriteOffs" xlink:label="loc_us-gaap_FinancingReceivableAllowanceForCreditLossesWriteOffs_50b6b70a-3a17-2c60-aef6-b9fd20b0ed62" xlink:type="locator" />
    <link:calculationArc order="1" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_rnst_FinancingReceivableAllowanceforCreditLossesNetRecoveriesWritedowns_aea21527-5355-6f03-8f6e-a767ae694cfe" xlink:to="loc_us-gaap_FinancingReceivableAllowanceForCreditLossesWriteOffs_50b6b70a-3a17-2c60-aef6-b9fd20b0ed62" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FinancingReceivableAllowanceForCreditLossesRecovery" xlink:label="loc_us-gaap_FinancingReceivableAllowanceForCreditLossesRecovery_f56ab924-0d81-da06-fe95-3a7e9fbed85e" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_rnst_FinancingReceivableAllowanceforCreditLossesNetRecoveriesWritedowns_aea21527-5355-6f03-8f6e-a767ae694cfe" xlink:to="loc_us-gaap_FinancingReceivableAllowanceForCreditLossesRecovery_f56ab924-0d81-da06-fe95-3a7e9fbed85e" xlink:type="arc" />
  </link:calculationLink>
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/AllowanceForLoanLossesDetails2" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/AllowanceForLoanLossesTables" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/CondensedConsolidatedStatementsOfCashFlowsUnaudited" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CashAndCashEquivalentsPeriodIncreaseDecrease" xlink:label="loc_us-gaap_CashAndCashEquivalentsPeriodIncreaseDecrease_dd2e9db6-10f9-d78a-ba84-b18268245a83" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_444b1ac7-f47a-4ce3-0caa-537f7e4ab8c3" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashAndCashEquivalentsPeriodIncreaseDecrease_dd2e9db6-10f9-d78a-ba84-b18268245a83" xlink:to="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_444b1ac7-f47a-4ce3-0caa-537f7e4ab8c3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_NetIncomeLoss" xlink:label="loc_us-gaap_NetIncomeLoss_641b1cab-a2b3-2e0e-8389-1455ff3f8581" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_444b1ac7-f47a-4ce3-0caa-537f7e4ab8c3" xlink:to="loc_us-gaap_NetIncomeLoss_641b1cab-a2b3-2e0e-8389-1455ff3f8581" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ProvisionForLoanAndLeaseLosses" xlink:label="loc_us-gaap_ProvisionForLoanAndLeaseLosses_e0ca8321-ebf3-2764-9c0e-6cfd763aef57" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_444b1ac7-f47a-4ce3-0caa-537f7e4ab8c3" xlink:to="loc_us-gaap_ProvisionForLoanAndLeaseLosses_e0ca8321-ebf3-2764-9c0e-6cfd763aef57" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DepreciationDepletionAndAmortization" xlink:label="loc_us-gaap_DepreciationDepletionAndAmortization_37b0c31d-5d8b-0577-dfd9-aa56a79334e3" xlink:type="locator" />
    <link:calculationArc order="3" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_444b1ac7-f47a-4ce3-0caa-537f7e4ab8c3" xlink:to="loc_us-gaap_DepreciationDepletionAndAmortization_37b0c31d-5d8b-0577-dfd9-aa56a79334e3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DeferredIncomeTaxExpenseBenefit" xlink:label="loc_us-gaap_DeferredIncomeTaxExpenseBenefit_f75d01b7-d271-b07d-c4a7-6ae60293303d" xlink:type="locator" />
    <link:calculationArc order="4" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_444b1ac7-f47a-4ce3-0caa-537f7e4ab8c3" xlink:to="loc_us-gaap_DeferredIncomeTaxExpenseBenefit_f75d01b7-d271-b07d-c4a7-6ae60293303d" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_PaymentsForOriginationOfMortgageLoansHeldForSale" xlink:label="loc_us-gaap_PaymentsForOriginationOfMortgageLoansHeldForSale_eb3d1f57-8afc-4e17-e4c5-077b3a40ad0f" xlink:type="locator" />
    <link:calculationArc order="5" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_444b1ac7-f47a-4ce3-0caa-537f7e4ab8c3" xlink:to="loc_us-gaap_PaymentsForOriginationOfMortgageLoansHeldForSale_eb3d1f57-8afc-4e17-e4c5-077b3a40ad0f" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ProceedsFromSaleOfMortgageLoansHeldForSale" xlink:label="loc_us-gaap_ProceedsFromSaleOfMortgageLoansHeldForSale_5caba4b5-7782-7990-af1d-b2b244c684d5" xlink:type="locator" />
    <link:calculationArc order="6" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_444b1ac7-f47a-4ce3-0caa-537f7e4ab8c3" xlink:to="loc_us-gaap_ProceedsFromSaleOfMortgageLoansHeldForSale_5caba4b5-7782-7990-af1d-b2b244c684d5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_GainLossOnSaleOfMortgageLoans" xlink:label="loc_us-gaap_GainLossOnSaleOfMortgageLoans_f4c28eed-0894-baf6-ebe8-d5e00ac1256c" xlink:type="locator" />
    <link:calculationArc order="7" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_444b1ac7-f47a-4ce3-0caa-537f7e4ab8c3" xlink:to="loc_us-gaap_GainLossOnSaleOfMortgageLoans_f4c28eed-0894-baf6-ebe8-d5e00ac1256c" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_GainLossOnSaleOfSecuritiesNet" xlink:label="loc_us-gaap_GainLossOnSaleOfSecuritiesNet_6798b2b8-2a12-21fe-9e3a-22ffb8e8a140" xlink:type="locator" />
    <link:calculationArc order="8" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_444b1ac7-f47a-4ce3-0caa-537f7e4ab8c3" xlink:to="loc_us-gaap_GainLossOnSaleOfSecuritiesNet_6798b2b8-2a12-21fe-9e3a-22ffb8e8a140" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_GainsLossesOnExtinguishmentOfDebt" xlink:label="loc_us-gaap_GainsLossesOnExtinguishmentOfDebt_3db65903-3171-d63c-a688-532ba00b8108" xlink:type="locator" />
    <link:calculationArc order="9" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_444b1ac7-f47a-4ce3-0caa-537f7e4ab8c3" xlink:to="loc_us-gaap_GainsLossesOnExtinguishmentOfDebt_3db65903-3171-d63c-a688-532ba00b8108" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_GainLossOnSaleOfPropertyPlantEquipment" xlink:label="loc_us-gaap_GainLossOnSaleOfPropertyPlantEquipment_5b3d4a64-864e-a67c-1d85-8163ad700c58" xlink:type="locator" />
    <link:calculationArc order="10" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_444b1ac7-f47a-4ce3-0caa-537f7e4ab8c3" xlink:to="loc_us-gaap_GainLossOnSaleOfPropertyPlantEquipment_5b3d4a64-864e-a67c-1d85-8163ad700c58" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ShareBasedCompensation" xlink:label="loc_us-gaap_ShareBasedCompensation_e3eecf87-b290-4567-8a59-5b0a8e27c85b" xlink:type="locator" />
    <link:calculationArc order="11" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_444b1ac7-f47a-4ce3-0caa-537f7e4ab8c3" xlink:to="loc_us-gaap_ShareBasedCompensation_e3eecf87-b290-4567-8a59-5b0a8e27c85b" xlink:type="arc" />
    <link:loc xlink:href="rnst-20170630.xsd#rnst_DecreaseInFederalDepositInsuranceCorporationLossShareIndemnificationAssetNetOfAccretion" xlink:label="loc_rnst_DecreaseInFederalDepositInsuranceCorporationLossShareIndemnificationAssetNetOfAccretion_9d099165-5a78-5df4-46db-a767adfe83a5" xlink:type="locator" />
    <link:calculationArc order="12" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_444b1ac7-f47a-4ce3-0caa-537f7e4ab8c3" xlink:to="loc_rnst_DecreaseInFederalDepositInsuranceCorporationLossShareIndemnificationAssetNetOfAccretion_9d099165-5a78-5df4-46db-a767adfe83a5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncreaseDecreaseInOtherOperatingAssets" xlink:label="loc_us-gaap_IncreaseDecreaseInOtherOperatingAssets_ac9066b4-6e40-13ed-8628-1a20304926d8" xlink:type="locator" />
    <link:calculationArc order="13" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_444b1ac7-f47a-4ce3-0caa-537f7e4ab8c3" xlink:to="loc_us-gaap_IncreaseDecreaseInOtherOperatingAssets_ac9066b4-6e40-13ed-8628-1a20304926d8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncreaseDecreaseInOtherOperatingLiabilities" xlink:label="loc_us-gaap_IncreaseDecreaseInOtherOperatingLiabilities_7e3bb724-19f9-7fc7-d3fb-60f34a11e15a" xlink:type="locator" />
    <link:calculationArc order="14" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_444b1ac7-f47a-4ce3-0caa-537f7e4ab8c3" xlink:to="loc_us-gaap_IncreaseDecreaseInOtherOperatingLiabilities_7e3bb724-19f9-7fc7-d3fb-60f34a11e15a" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_70319186-e7bd-7189-88d2-eba26fb93350" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashAndCashEquivalentsPeriodIncreaseDecrease_dd2e9db6-10f9-d78a-ba84-b18268245a83" xlink:to="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_70319186-e7bd-7189-88d2-eba26fb93350" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_PaymentsToAcquireAvailableForSaleSecurities" xlink:label="loc_us-gaap_PaymentsToAcquireAvailableForSaleSecurities_9cebbd9b-269e-5a19-54b8-1c32e2660d83" xlink:type="locator" />
    <link:calculationArc order="1" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_70319186-e7bd-7189-88d2-eba26fb93350" xlink:to="loc_us-gaap_PaymentsToAcquireAvailableForSaleSecurities_9cebbd9b-269e-5a19-54b8-1c32e2660d83" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ProceedsFromSaleOfAvailableForSaleSecurities" xlink:label="loc_us-gaap_ProceedsFromSaleOfAvailableForSaleSecurities_d3d89aab-5be8-f6a4-66e9-41f55e0839cd" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_70319186-e7bd-7189-88d2-eba26fb93350" xlink:to="loc_us-gaap_ProceedsFromSaleOfAvailableForSaleSecurities_d3d89aab-5be8-f6a4-66e9-41f55e0839cd" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities" xlink:label="loc_us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities_b49c7a2f-2986-824d-e7cb-bc082ac0e888" xlink:type="locator" />
    <link:calculationArc order="3" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_70319186-e7bd-7189-88d2-eba26fb93350" xlink:to="loc_us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfAvailableForSaleSecurities_b49c7a2f-2986-824d-e7cb-bc082ac0e888" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_PaymentsToAcquireHeldToMaturitySecurities" xlink:label="loc_us-gaap_PaymentsToAcquireHeldToMaturitySecurities_3a5a60fd-6807-00fa-b758-39b7b6e16f8a" xlink:type="locator" />
    <link:calculationArc order="4" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_70319186-e7bd-7189-88d2-eba26fb93350" xlink:to="loc_us-gaap_PaymentsToAcquireHeldToMaturitySecurities_3a5a60fd-6807-00fa-b758-39b7b6e16f8a" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfHeldToMaturitySecurities" xlink:label="loc_us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfHeldToMaturitySecurities_0de8de13-3824-9d0d-a270-12d0f2fbdb58" xlink:type="locator" />
    <link:calculationArc order="5" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_70319186-e7bd-7189-88d2-eba26fb93350" xlink:to="loc_us-gaap_ProceedsFromMaturitiesPrepaymentsAndCallsOfHeldToMaturitySecurities_0de8de13-3824-9d0d-a270-12d0f2fbdb58" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_PaymentsForProceedsFromLoansAndLeases" xlink:label="loc_us-gaap_PaymentsForProceedsFromLoansAndLeases_c84002e7-fa43-cc52-024d-b47cc02aa671" xlink:type="locator" />
    <link:calculationArc order="6" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_70319186-e7bd-7189-88d2-eba26fb93350" xlink:to="loc_us-gaap_PaymentsForProceedsFromLoansAndLeases_c84002e7-fa43-cc52-024d-b47cc02aa671" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_PaymentsToAcquirePropertyPlantAndEquipment" xlink:label="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_fee12b15-6b42-6245-2e2f-ff030b98332c" xlink:type="locator" />
    <link:calculationArc order="7" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_70319186-e7bd-7189-88d2-eba26fb93350" xlink:to="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_fee12b15-6b42-6245-2e2f-ff030b98332c" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ProceedsFromSaleOfPropertyPlantAndEquipment" xlink:label="loc_us-gaap_ProceedsFromSaleOfPropertyPlantAndEquipment_f7ed6106-862d-edb5-3fd1-677e7651af64" xlink:type="locator" />
    <link:calculationArc order="8" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_70319186-e7bd-7189-88d2-eba26fb93350" xlink:to="loc_us-gaap_ProceedsFromSaleOfPropertyPlantAndEquipment_f7ed6106-862d-edb5-3fd1-677e7651af64" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ProceedsFromSaleOfOtherAssetsInvestingActivities" xlink:label="loc_us-gaap_ProceedsFromSaleOfOtherAssetsInvestingActivities_24ed0e48-9c9c-5922-c409-f6dbe196e9a6" xlink:type="locator" />
    <link:calculationArc order="9" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_70319186-e7bd-7189-88d2-eba26fb93350" xlink:to="loc_us-gaap_ProceedsFromSaleOfOtherAssetsInvestingActivities_24ed0e48-9c9c-5922-c409-f6dbe196e9a6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CashAcquiredFromAcquisition" xlink:label="loc_us-gaap_CashAcquiredFromAcquisition_207a1788-de98-876d-55d2-2ec6bb7931f8" xlink:type="locator" />
    <link:calculationArc order="10" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_70319186-e7bd-7189-88d2-eba26fb93350" xlink:to="loc_us-gaap_CashAcquiredFromAcquisition_207a1788-de98-876d-55d2-2ec6bb7931f8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_deb49b68-c030-7624-a39d-ea301caa5dbf" xlink:type="locator" />
    <link:calculationArc order="3" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashAndCashEquivalentsPeriodIncreaseDecrease_dd2e9db6-10f9-d78a-ba84-b18268245a83" xlink:to="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_deb49b68-c030-7624-a39d-ea301caa5dbf" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_NetChangeNoninterestBearingDepositsDomestic" xlink:label="loc_us-gaap_NetChangeNoninterestBearingDepositsDomestic_9baab413-5e98-e353-d089-dea88add92d5" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_deb49b68-c030-7624-a39d-ea301caa5dbf" xlink:to="loc_us-gaap_NetChangeNoninterestBearingDepositsDomestic_9baab413-5e98-e353-d089-dea88add92d5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_NetChangeInterestBearingDepositsDomestic" xlink:label="loc_us-gaap_NetChangeInterestBearingDepositsDomestic_d48d423f-6d78-f16c-3022-2d16ef757d19" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_deb49b68-c030-7624-a39d-ea301caa5dbf" xlink:to="loc_us-gaap_NetChangeInterestBearingDepositsDomestic_d48d423f-6d78-f16c-3022-2d16ef757d19" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ProceedsFromRepaymentsOfShortTermDebt" xlink:label="loc_us-gaap_ProceedsFromRepaymentsOfShortTermDebt_27f3e695-baed-1adc-cc35-793c3b76e4f9" xlink:type="locator" />
    <link:calculationArc order="3" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_deb49b68-c030-7624-a39d-ea301caa5dbf" xlink:to="loc_us-gaap_ProceedsFromRepaymentsOfShortTermDebt_27f3e695-baed-1adc-cc35-793c3b76e4f9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ProceedsFromIssuanceOfLongTermDebt" xlink:label="loc_us-gaap_ProceedsFromIssuanceOfLongTermDebt_e5f1c7a4-b42a-8461-2001-b1f20e51b257" xlink:type="locator" />
    <link:calculationArc order="4" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_deb49b68-c030-7624-a39d-ea301caa5dbf" xlink:to="loc_us-gaap_ProceedsFromIssuanceOfLongTermDebt_e5f1c7a4-b42a-8461-2001-b1f20e51b257" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RepaymentsOfLongTermDebt" xlink:label="loc_us-gaap_RepaymentsOfLongTermDebt_2b72fe5f-3c0e-d5e0-8e5c-ad01818e58e5" xlink:type="locator" />
    <link:calculationArc order="5" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_deb49b68-c030-7624-a39d-ea301caa5dbf" xlink:to="loc_us-gaap_RepaymentsOfLongTermDebt_2b72fe5f-3c0e-d5e0-8e5c-ad01818e58e5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_PaymentsOfDividends" xlink:label="loc_us-gaap_PaymentsOfDividends_11043fe8-215b-8e23-9bde-984dc82a0339" xlink:type="locator" />
    <link:calculationArc order="6" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_deb49b68-c030-7624-a39d-ea301caa5dbf" xlink:to="loc_us-gaap_PaymentsOfDividends_11043fe8-215b-8e23-9bde-984dc82a0339" xlink:type="arc" />
    <link:loc xlink:href="rnst-20170630.xsd#rnst_PaymentsRelatedtoTaxWithholdingforSharebasedCompensationNetofProceedsfromExerciseofStockOptions" xlink:label="loc_rnst_PaymentsRelatedtoTaxWithholdingforSharebasedCompensationNetofProceedsfromExerciseofStockOptions_6bcabe94-c4dd-635c-a809-a767ab3f739a" xlink:type="locator" />
    <link:calculationArc order="7" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_deb49b68-c030-7624-a39d-ea301caa5dbf" xlink:to="loc_rnst_PaymentsRelatedtoTaxWithholdingforSharebasedCompensationNetofProceedsfromExerciseofStockOptions_6bcabe94-c4dd-635c-a809-a767ab3f739a" xlink:type="arc" />
    <link:loc xlink:href="rnst-20170630.xsd#rnst_ExcessTaxBenefitfromPaymentsRelatedtoSharebasedCompensationFinancingActivities" xlink:label="loc_rnst_ExcessTaxBenefitfromPaymentsRelatedtoSharebasedCompensationFinancingActivities_48063186-a3f2-def5-d1d3-a767ac62c749" xlink:type="locator" />
    <link:calculationArc order="8" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_deb49b68-c030-7624-a39d-ea301caa5dbf" xlink:to="loc_rnst_ExcessTaxBenefitfromPaymentsRelatedtoSharebasedCompensationFinancingActivities_48063186-a3f2-def5-d1d3-a767ac62c749" xlink:type="arc" />
  </link:calculationLink>
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/ConsolidatedBalanceSheets" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_Assets" xlink:label="loc_us-gaap_Assets_c6057b1d-6685-8249-2051-6c57f3a16a9e" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue" xlink:label="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_07da1db4-2708-4446-4250-1fdd5956185e" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_c6057b1d-6685-8249-2051-6c57f3a16a9e" xlink:to="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_07da1db4-2708-4446-4250-1fdd5956185e" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CashAndDueFromBanks" xlink:label="loc_us-gaap_CashAndDueFromBanks_6ea59cdf-420f-0221-a162-87e84408dc3b" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_07da1db4-2708-4446-4250-1fdd5956185e" xlink:to="loc_us-gaap_CashAndDueFromBanks_6ea59cdf-420f-0221-a162-87e84408dc3b" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_InterestBearingDepositsInBanks" xlink:label="loc_us-gaap_InterestBearingDepositsInBanks_75c23f4c-57d7-1642-0f06-8805879e7b8d" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_07da1db4-2708-4446-4250-1fdd5956185e" xlink:to="loc_us-gaap_InterestBearingDepositsInBanks_75c23f4c-57d7-1642-0f06-8805879e7b8d" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_HeldToMaturitySecurities" xlink:label="loc_us-gaap_HeldToMaturitySecurities_3bb8bc81-af51-9945-0a22-cc4527e07a17" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_c6057b1d-6685-8249-2051-6c57f3a16a9e" xlink:to="loc_us-gaap_HeldToMaturitySecurities_3bb8bc81-af51-9945-0a22-cc4527e07a17" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AvailableForSaleSecurities" xlink:label="loc_us-gaap_AvailableForSaleSecurities_d444402b-921b-e0fa-119c-908ab66850af" xlink:type="locator" />
    <link:calculationArc order="3" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_c6057b1d-6685-8249-2051-6c57f3a16a9e" xlink:to="loc_us-gaap_AvailableForSaleSecurities_d444402b-921b-e0fa-119c-908ab66850af" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LoansReceivableHeldForSaleNetNotPartOfDisposalGroupMortgage" xlink:label="loc_us-gaap_LoansReceivableHeldForSaleNetNotPartOfDisposalGroupMortgage_00075edd-448d-bc2f-ab80-e37f3fff9f6e" xlink:type="locator" />
    <link:calculationArc order="4" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_c6057b1d-6685-8249-2051-6c57f3a16a9e" xlink:to="loc_us-gaap_LoansReceivableHeldForSaleNetNotPartOfDisposalGroupMortgage_00075edd-448d-bc2f-ab80-e37f3fff9f6e" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LoansAndLeasesReceivableNetReportedAmountCoveredAndNotCovered" xlink:label="loc_us-gaap_LoansAndLeasesReceivableNetReportedAmountCoveredAndNotCovered_b7f53a0f-a08e-9b8c-f6ba-2f74aa6b744a" xlink:type="locator" />
    <link:calculationArc order="5" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_c6057b1d-6685-8249-2051-6c57f3a16a9e" xlink:to="loc_us-gaap_LoansAndLeasesReceivableNetReportedAmountCoveredAndNotCovered_b7f53a0f-a08e-9b8c-f6ba-2f74aa6b744a" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LoansAndLeasesReceivableNetOfDeferredIncome" xlink:label="loc_us-gaap_LoansAndLeasesReceivableNetOfDeferredIncome_99b7c0b8-78d1-c66a-eb0a-fb20f225718b" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LoansAndLeasesReceivableNetReportedAmountCoveredAndNotCovered_b7f53a0f-a08e-9b8c-f6ba-2f74aa6b744a" xlink:to="loc_us-gaap_LoansAndLeasesReceivableNetOfDeferredIncome_99b7c0b8-78d1-c66a-eb0a-fb20f225718b" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LoansAndLeasesReceivableAllowance" xlink:label="loc_us-gaap_LoansAndLeasesReceivableAllowance_8e1c2ae9-243e-baf4-cc90-3e520d158505" xlink:type="locator" />
    <link:calculationArc order="2" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LoansAndLeasesReceivableNetReportedAmountCoveredAndNotCovered_b7f53a0f-a08e-9b8c-f6ba-2f74aa6b744a" xlink:to="loc_us-gaap_LoansAndLeasesReceivableAllowance_8e1c2ae9-243e-baf4-cc90-3e520d158505" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_PropertyPlantAndEquipmentNet" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentNet_1944a381-5c4e-ce3c-9111-13ccd1c639db" xlink:type="locator" />
    <link:calculationArc order="6" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_c6057b1d-6685-8249-2051-6c57f3a16a9e" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentNet_1944a381-5c4e-ce3c-9111-13ccd1c639db" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherRealEstateAndForeclosedAssets" xlink:label="loc_us-gaap_OtherRealEstateAndForeclosedAssets_981e6fe7-fa32-4b68-a956-d14acea056c4" xlink:type="locator" />
    <link:calculationArc order="7" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_c6057b1d-6685-8249-2051-6c57f3a16a9e" xlink:to="loc_us-gaap_OtherRealEstateAndForeclosedAssets_981e6fe7-fa32-4b68-a956-d14acea056c4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_Goodwill" xlink:label="loc_us-gaap_Goodwill_93a64cae-271a-5e6b-8c83-5adf9f941142" xlink:type="locator" />
    <link:calculationArc order="8" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_c6057b1d-6685-8249-2051-6c57f3a16a9e" xlink:to="loc_us-gaap_Goodwill_93a64cae-271a-5e6b-8c83-5adf9f941142" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IntangibleAssetsNetExcludingGoodwill" xlink:label="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_1fe06082-076b-052d-6e2e-930afe9d6b2d" xlink:type="locator" />
    <link:calculationArc order="9" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_c6057b1d-6685-8249-2051-6c57f3a16a9e" xlink:to="loc_us-gaap_IntangibleAssetsNetExcludingGoodwill_1fe06082-076b-052d-6e2e-930afe9d6b2d" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BankOwnedLifeInsurance" xlink:label="loc_us-gaap_BankOwnedLifeInsurance_018f383f-2509-5672-bb2d-340e9af33c38" xlink:type="locator" />
    <link:calculationArc order="10" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_c6057b1d-6685-8249-2051-6c57f3a16a9e" xlink:to="loc_us-gaap_BankOwnedLifeInsurance_018f383f-2509-5672-bb2d-340e9af33c38" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherAssets" xlink:label="loc_us-gaap_OtherAssets_cb56b01f-b9c5-ca9e-8988-e23b27fc7a20" xlink:type="locator" />
    <link:calculationArc order="11" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_c6057b1d-6685-8249-2051-6c57f3a16a9e" xlink:to="loc_us-gaap_OtherAssets_cb56b01f-b9c5-ca9e-8988-e23b27fc7a20" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ServicingAsset" xlink:label="loc_us-gaap_ServicingAsset_9ee3a917-ceec-454e-8153-1fdc73683706" xlink:type="locator" />
    <link:calculationArc order="12" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Assets_c6057b1d-6685-8249-2051-6c57f3a16a9e" xlink:to="loc_us-gaap_ServicingAsset_9ee3a917-ceec-454e-8153-1fdc73683706" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LiabilitiesAndStockholdersEquity" xlink:label="loc_us-gaap_LiabilitiesAndStockholdersEquity_159dcb00-b17e-17db-7098-be4159799459" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_Liabilities" xlink:label="loc_us-gaap_Liabilities_d8bb821f-d155-9d4e-1738-736b4bf4cb19" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_159dcb00-b17e-17db-7098-be4159799459" xlink:to="loc_us-gaap_Liabilities_d8bb821f-d155-9d4e-1738-736b4bf4cb19" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_Deposits" xlink:label="loc_us-gaap_Deposits_20926415-8452-ba54-f959-6378e08cdab1" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Liabilities_d8bb821f-d155-9d4e-1738-736b4bf4cb19" xlink:to="loc_us-gaap_Deposits_20926415-8452-ba54-f959-6378e08cdab1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_NoninterestBearingDepositLiabilities" xlink:label="loc_us-gaap_NoninterestBearingDepositLiabilities_bd883c76-dce0-8aaf-554a-8adc97b467c6" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Deposits_20926415-8452-ba54-f959-6378e08cdab1" xlink:to="loc_us-gaap_NoninterestBearingDepositLiabilities_bd883c76-dce0-8aaf-554a-8adc97b467c6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_InterestBearingDepositLiabilities" xlink:label="loc_us-gaap_InterestBearingDepositLiabilities_03a04562-5601-ae4a-858b-4b7609367170" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Deposits_20926415-8452-ba54-f959-6378e08cdab1" xlink:to="loc_us-gaap_InterestBearingDepositLiabilities_03a04562-5601-ae4a-858b-4b7609367170" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ShortTermBorrowings" xlink:label="loc_us-gaap_ShortTermBorrowings_c4493b41-4418-ed41-2f06-05ff9c61369f" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Liabilities_d8bb821f-d155-9d4e-1738-736b4bf4cb19" xlink:to="loc_us-gaap_ShortTermBorrowings_c4493b41-4418-ed41-2f06-05ff9c61369f" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LongTermDebt" xlink:label="loc_us-gaap_LongTermDebt_7e14882f-7ab9-8302-20ff-24c510ab8806" xlink:type="locator" />
    <link:calculationArc order="3" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Liabilities_d8bb821f-d155-9d4e-1738-736b4bf4cb19" xlink:to="loc_us-gaap_LongTermDebt_7e14882f-7ab9-8302-20ff-24c510ab8806" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherLiabilities" xlink:label="loc_us-gaap_OtherLiabilities_81d717e1-3e46-8423-3e5f-d98aacc74856" xlink:type="locator" />
    <link:calculationArc order="4" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_Liabilities_d8bb821f-d155-9d4e-1738-736b4bf4cb19" xlink:to="loc_us-gaap_OtherLiabilities_81d717e1-3e46-8423-3e5f-d98aacc74856" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_StockholdersEquity" xlink:label="loc_us-gaap_StockholdersEquity_4b158f76-5f04-5e4d-ead3-d80e1f9943db" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquity_159dcb00-b17e-17db-7098-be4159799459" xlink:to="loc_us-gaap_StockholdersEquity_4b158f76-5f04-5e4d-ead3-d80e1f9943db" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_PreferredStockValue" xlink:label="loc_us-gaap_PreferredStockValue_4fb6195d-d905-dac7-e5a0-79f324993f79" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_4b158f76-5f04-5e4d-ead3-d80e1f9943db" xlink:to="loc_us-gaap_PreferredStockValue_4fb6195d-d905-dac7-e5a0-79f324993f79" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CommonStockValue" xlink:label="loc_us-gaap_CommonStockValue_c3f7606a-e7e9-61d5-b60b-b4b059f68b26" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_4b158f76-5f04-5e4d-ead3-d80e1f9943db" xlink:to="loc_us-gaap_CommonStockValue_c3f7606a-e7e9-61d5-b60b-b4b059f68b26" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_TreasuryStockValue" xlink:label="loc_us-gaap_TreasuryStockValue_40678492-c421-af67-b276-f663f9ff2f98" xlink:type="locator" />
    <link:calculationArc order="3" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_4b158f76-5f04-5e4d-ead3-d80e1f9943db" xlink:to="loc_us-gaap_TreasuryStockValue_40678492-c421-af67-b276-f663f9ff2f98" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AdditionalPaidInCapital" xlink:label="loc_us-gaap_AdditionalPaidInCapital_2d1b9d27-8b19-82d9-2843-5b3d292b7fbb" xlink:type="locator" />
    <link:calculationArc order="4" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_4b158f76-5f04-5e4d-ead3-d80e1f9943db" xlink:to="loc_us-gaap_AdditionalPaidInCapital_2d1b9d27-8b19-82d9-2843-5b3d292b7fbb" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RetainedEarningsAccumulatedDeficit" xlink:label="loc_us-gaap_RetainedEarningsAccumulatedDeficit_065cb284-7fca-cc9b-5752-2feaf74d0011" xlink:type="locator" />
    <link:calculationArc order="5" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_4b158f76-5f04-5e4d-ead3-d80e1f9943db" xlink:to="loc_us-gaap_RetainedEarningsAccumulatedDeficit_065cb284-7fca-cc9b-5752-2feaf74d0011" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_04f0961a-a0bc-88cf-6658-3f950da4a458" xlink:type="locator" />
    <link:calculationArc order="6" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_StockholdersEquity_4b158f76-5f04-5e4d-ead3-d80e1f9943db" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_04f0961a-a0bc-88cf-6658-3f950da4a458" xlink:type="arc" />
  </link:calculationLink>
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/ConsolidatedBalanceSheetsParenthetical" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/ConsolidatedStatementsOfComprehensiveIncomeUnaudited" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ComprehensiveIncomeNetOfTax" xlink:label="loc_us-gaap_ComprehensiveIncomeNetOfTax_499015ce-2160-aed2-85a3-080e8c4c6cdf" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_NetIncomeLoss" xlink:label="loc_us-gaap_NetIncomeLoss_641b1cab-a2b3-2e0e-8389-1455ff3f8581" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_ComprehensiveIncomeNetOfTax_499015ce-2160-aed2-85a3-080e8c4c6cdf" xlink:to="loc_us-gaap_NetIncomeLoss_641b1cab-a2b3-2e0e-8389-1455ff3f8581" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTax" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTax_2a6e77d2-a694-61f8-1c68-085fd849c780" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_ComprehensiveIncomeNetOfTax_499015ce-2160-aed2-85a3-080e8c4c6cdf" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTax_2a6e77d2-a694-61f8-1c68-085fd849c780" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax_548688b8-2d34-462c-5a92-aa79f1c44c1a" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTax_2a6e77d2-a694-61f8-1c68-085fd849c780" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax_548688b8-2d34-462c-5a92-aa79f1c44c1a" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax" xlink:label="loc_us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax_57e8ae74-d8b6-c629-9bee-2d0929cd3999" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax_548688b8-2d34-462c-5a92-aa79f1c44c1a" xlink:to="loc_us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax_57e8ae74-d8b6-c629-9bee-2d0929cd3999" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossReclassificationAdjustmentFromAOCIForSaleOfSecuritiesNetOfTax" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossReclassificationAdjustmentFromAOCIForSaleOfSecuritiesNetOfTax_ab3008c3-c5c2-a86b-0613-39cbd9b94527" xlink:type="locator" />
    <link:calculationArc order="2" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax_548688b8-2d34-462c-5a92-aa79f1c44c1a" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossReclassificationAdjustmentFromAOCIForSaleOfSecuritiesNetOfTax_ab3008c3-c5c2-a86b-0613-39cbd9b94527" xlink:type="arc" />
    <link:loc xlink:href="rnst-20170630.xsd#rnst_AmortizationOfUnrealizedHoldingGainsOnSecuritiesTransferredToHeldToMaturityCategory" xlink:label="loc_rnst_AmortizationOfUnrealizedHoldingGainsOnSecuritiesTransferredToHeldToMaturityCategory_47b313f7-b24c-76dc-327f-a767af319386" xlink:type="locator" />
    <link:calculationArc order="3" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax_548688b8-2d34-462c-5a92-aa79f1c44c1a" xlink:to="loc_rnst_AmortizationOfUnrealizedHoldingGainsOnSecuritiesTransferredToHeldToMaturityCategory_47b313f7-b24c-76dc-327f-a767af319386" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossDerivativesQualifyingAsHedgesNetOfTax" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossDerivativesQualifyingAsHedgesNetOfTax_cc7c59d2-21ac-163e-0898-1c1f212ef02b" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTax_2a6e77d2-a694-61f8-1c68-085fd849c780" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossDerivativesQualifyingAsHedgesNetOfTax_cc7c59d2-21ac-163e-0898-1c1f212ef02b" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherComprehensiveIncomeUnrealizedGainLossOnDerivativesArisingDuringPeriodNetOfTax" xlink:label="loc_us-gaap_OtherComprehensiveIncomeUnrealizedGainLossOnDerivativesArisingDuringPeriodNetOfTax_6feed690-17e1-a928-d1c5-204f2faa570e" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossDerivativesQualifyingAsHedgesNetOfTax_cc7c59d2-21ac-163e-0898-1c1f212ef02b" xlink:to="loc_us-gaap_OtherComprehensiveIncomeUnrealizedGainLossOnDerivativesArisingDuringPeriodNetOfTax_6feed690-17e1-a928-d1c5-204f2faa570e" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossPensionAndOtherPostretirementBenefitPlansAdjustmentNetOfTax" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossPensionAndOtherPostretirementBenefitPlansAdjustmentNetOfTax_2652b636-1a3b-e639-2800-d9ed5b9b4fc0" xlink:type="locator" />
    <link:calculationArc order="3" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTax_2a6e77d2-a694-61f8-1c68-085fd849c780" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossPensionAndOtherPostretirementBenefitPlansAdjustmentNetOfTax_2652b636-1a3b-e639-2800-d9ed5b9b4fc0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossReclassificationAdjustmentFromAOCIPensionAndOtherPostretirementBenefitPlansForNetGainLossNetOfTax" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossReclassificationAdjustmentFromAOCIPensionAndOtherPostretirementBenefitPlansForNetGainLossNetOfTax_eea0c679-aff6-c974-47a0-ff7e9cae6086" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossPensionAndOtherPostretirementBenefitPlansAdjustmentNetOfTax_2652b636-1a3b-e639-2800-d9ed5b9b4fc0" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossReclassificationAdjustmentFromAOCIPensionAndOtherPostretirementBenefitPlansForNetGainLossNetOfTax_eea0c679-aff6-c974-47a0-ff7e9cae6086" xlink:type="arc" />
  </link:calculationLink>
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/ConsolidatedStatementsOfIncomeUnaudited" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_NetIncomeLoss" xlink:label="loc_us-gaap_NetIncomeLoss_641b1cab-a2b3-2e0e-8389-1455ff3f8581" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_0eb47183-f513-314d-ceda-ee2412d9eee8" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetIncomeLoss_641b1cab-a2b3-2e0e-8389-1455ff3f8581" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_0eb47183-f513-314d-ceda-ee2412d9eee8" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_InterestIncomeExpenseAfterProvisionForLoanLoss" xlink:label="loc_us-gaap_InterestIncomeExpenseAfterProvisionForLoanLoss_4b7a9f96-e361-95dc-567f-7c30db8e2c0d" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_0eb47183-f513-314d-ceda-ee2412d9eee8" xlink:to="loc_us-gaap_InterestIncomeExpenseAfterProvisionForLoanLoss_4b7a9f96-e361-95dc-567f-7c30db8e2c0d" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_InterestIncomeExpenseNet" xlink:label="loc_us-gaap_InterestIncomeExpenseNet_1df5100d-c7c3-27c8-1405-81abbd3827e1" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InterestIncomeExpenseAfterProvisionForLoanLoss_4b7a9f96-e361-95dc-567f-7c30db8e2c0d" xlink:to="loc_us-gaap_InterestIncomeExpenseNet_1df5100d-c7c3-27c8-1405-81abbd3827e1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_InterestAndDividendIncomeOperating" xlink:label="loc_us-gaap_InterestAndDividendIncomeOperating_4477516e-3843-f1b4-8a61-de669ff8f0e0" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InterestIncomeExpenseNet_1df5100d-c7c3-27c8-1405-81abbd3827e1" xlink:to="loc_us-gaap_InterestAndDividendIncomeOperating_4477516e-3843-f1b4-8a61-de669ff8f0e0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_InterestAndFeeIncomeLoansAndLeases" xlink:label="loc_us-gaap_InterestAndFeeIncomeLoansAndLeases_73eb116a-244c-faca-8f1b-fa72559b1ebe" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InterestAndDividendIncomeOperating_4477516e-3843-f1b4-8a61-de669ff8f0e0" xlink:to="loc_us-gaap_InterestAndFeeIncomeLoansAndLeases_73eb116a-244c-faca-8f1b-fa72559b1ebe" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_InterestIncomeSecuritiesTaxable" xlink:label="loc_us-gaap_InterestIncomeSecuritiesTaxable_8eeb6f23-0d88-2477-9de1-6ce7e482d4b6" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InterestAndDividendIncomeOperating_4477516e-3843-f1b4-8a61-de669ff8f0e0" xlink:to="loc_us-gaap_InterestIncomeSecuritiesTaxable_8eeb6f23-0d88-2477-9de1-6ce7e482d4b6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_InterestIncomeSecuritiesTaxExempt" xlink:label="loc_us-gaap_InterestIncomeSecuritiesTaxExempt_85ed5e03-4038-047b-5c67-89989f46ca8b" xlink:type="locator" />
    <link:calculationArc order="3" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InterestAndDividendIncomeOperating_4477516e-3843-f1b4-8a61-de669ff8f0e0" xlink:to="loc_us-gaap_InterestIncomeSecuritiesTaxExempt_85ed5e03-4038-047b-5c67-89989f46ca8b" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherInterestAndDividendIncome" xlink:label="loc_us-gaap_OtherInterestAndDividendIncome_e7190940-6dd9-cccb-7cdc-ad2fcbe3a626" xlink:type="locator" />
    <link:calculationArc order="4" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InterestAndDividendIncomeOperating_4477516e-3843-f1b4-8a61-de669ff8f0e0" xlink:to="loc_us-gaap_OtherInterestAndDividendIncome_e7190940-6dd9-cccb-7cdc-ad2fcbe3a626" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_InterestExpense" xlink:label="loc_us-gaap_InterestExpense_7c9599ab-2a77-022c-c720-63fecff6a62c" xlink:type="locator" />
    <link:calculationArc order="2" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InterestIncomeExpenseNet_1df5100d-c7c3-27c8-1405-81abbd3827e1" xlink:to="loc_us-gaap_InterestExpense_7c9599ab-2a77-022c-c720-63fecff6a62c" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_InterestExpenseDeposits" xlink:label="loc_us-gaap_InterestExpenseDeposits_1b3f3aad-0663-6434-2e85-258ef2ba8cf4" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InterestExpense_7c9599ab-2a77-022c-c720-63fecff6a62c" xlink:to="loc_us-gaap_InterestExpenseDeposits_1b3f3aad-0663-6434-2e85-258ef2ba8cf4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_InterestExpenseBorrowings" xlink:label="loc_us-gaap_InterestExpenseBorrowings_e1350110-0ab0-e3d3-11df-192dceb7e187" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InterestExpense_7c9599ab-2a77-022c-c720-63fecff6a62c" xlink:to="loc_us-gaap_InterestExpenseBorrowings_e1350110-0ab0-e3d3-11df-192dceb7e187" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ProvisionForLoanAndLeaseLosses" xlink:label="loc_us-gaap_ProvisionForLoanAndLeaseLosses_e0ca8321-ebf3-2764-9c0e-6cfd763aef57" xlink:type="locator" />
    <link:calculationArc order="2" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_InterestIncomeExpenseAfterProvisionForLoanLoss_4b7a9f96-e361-95dc-567f-7c30db8e2c0d" xlink:to="loc_us-gaap_ProvisionForLoanAndLeaseLosses_e0ca8321-ebf3-2764-9c0e-6cfd763aef57" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_NoninterestIncome" xlink:label="loc_us-gaap_NoninterestIncome_85d8e349-2d49-3422-00b4-05065a60f6f9" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_0eb47183-f513-314d-ceda-ee2412d9eee8" xlink:to="loc_us-gaap_NoninterestIncome_85d8e349-2d49-3422-00b4-05065a60f6f9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FeesAndCommissionsDepositorAccounts" xlink:label="loc_us-gaap_FeesAndCommissionsDepositorAccounts_a4fbc5df-70a9-e2bd-ec71-0fe6359f2eee" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NoninterestIncome_85d8e349-2d49-3422-00b4-05065a60f6f9" xlink:to="loc_us-gaap_FeesAndCommissionsDepositorAccounts_a4fbc5df-70a9-e2bd-ec71-0fe6359f2eee" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FeesAndCommissions" xlink:label="loc_us-gaap_FeesAndCommissions_2724484e-537a-353c-8eec-b7499cb06fff" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NoninterestIncome_85d8e349-2d49-3422-00b4-05065a60f6f9" xlink:to="loc_us-gaap_FeesAndCommissions_2724484e-537a-353c-8eec-b7499cb06fff" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_InsuranceCommissionsAndFees" xlink:label="loc_us-gaap_InsuranceCommissionsAndFees_3b23ed3c-3949-15b2-a061-1a0d131912ee" xlink:type="locator" />
    <link:calculationArc order="3" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NoninterestIncome_85d8e349-2d49-3422-00b4-05065a60f6f9" xlink:to="loc_us-gaap_InsuranceCommissionsAndFees_3b23ed3c-3949-15b2-a061-1a0d131912ee" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FeesAndCommissionsFiduciaryAndTrustActivities" xlink:label="loc_us-gaap_FeesAndCommissionsFiduciaryAndTrustActivities_a0a09439-f676-5b44-5d17-fb305f94c8ad" xlink:type="locator" />
    <link:calculationArc order="4" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NoninterestIncome_85d8e349-2d49-3422-00b4-05065a60f6f9" xlink:to="loc_us-gaap_FeesAndCommissionsFiduciaryAndTrustActivities_a0a09439-f676-5b44-5d17-fb305f94c8ad" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FeesAndCommissionsMortgageBanking" xlink:label="loc_us-gaap_FeesAndCommissionsMortgageBanking_1dad8197-bb1a-112c-18dc-ed6b864c03a5" xlink:type="locator" />
    <link:calculationArc order="5" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NoninterestIncome_85d8e349-2d49-3422-00b4-05065a60f6f9" xlink:to="loc_us-gaap_FeesAndCommissionsMortgageBanking_1dad8197-bb1a-112c-18dc-ed6b864c03a5" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_GainLossOnSaleOfSecuritiesNet" xlink:label="loc_us-gaap_GainLossOnSaleOfSecuritiesNet_6798b2b8-2a12-21fe-9e3a-22ffb8e8a140" xlink:type="locator" />
    <link:calculationArc order="6" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NoninterestIncome_85d8e349-2d49-3422-00b4-05065a60f6f9" xlink:to="loc_us-gaap_GainLossOnSaleOfSecuritiesNet_6798b2b8-2a12-21fe-9e3a-22ffb8e8a140" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BankOwnedLifeInsuranceIncome" xlink:label="loc_us-gaap_BankOwnedLifeInsuranceIncome_4cbe5c15-9ded-be02-3fa0-35d770913236" xlink:type="locator" />
    <link:calculationArc order="7" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NoninterestIncome_85d8e349-2d49-3422-00b4-05065a60f6f9" xlink:to="loc_us-gaap_BankOwnedLifeInsuranceIncome_4cbe5c15-9ded-be02-3fa0-35d770913236" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_NoninterestIncomeOtherOperatingIncome" xlink:label="loc_us-gaap_NoninterestIncomeOtherOperatingIncome_bbc2d8f2-839a-169c-6677-9e1bd2a87a11" xlink:type="locator" />
    <link:calculationArc order="8" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NoninterestIncome_85d8e349-2d49-3422-00b4-05065a60f6f9" xlink:to="loc_us-gaap_NoninterestIncomeOtherOperatingIncome_bbc2d8f2-839a-169c-6677-9e1bd2a87a11" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_NoninterestExpense" xlink:label="loc_us-gaap_NoninterestExpense_b9eb1ceb-6771-3351-1281-e8b3cd4f24bc" xlink:type="locator" />
    <link:calculationArc order="3" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_0eb47183-f513-314d-ceda-ee2412d9eee8" xlink:to="loc_us-gaap_NoninterestExpense_b9eb1ceb-6771-3351-1281-e8b3cd4f24bc" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LaborAndRelatedExpense" xlink:label="loc_us-gaap_LaborAndRelatedExpense_f279d790-3f69-6bb0-bf56-02597d072677" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NoninterestExpense_b9eb1ceb-6771-3351-1281-e8b3cd4f24bc" xlink:to="loc_us-gaap_LaborAndRelatedExpense_f279d790-3f69-6bb0-bf56-02597d072677" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_InformationTechnologyAndDataProcessing" xlink:label="loc_us-gaap_InformationTechnologyAndDataProcessing_362f9a0f-7f2d-746c-6a38-3815f0270d4b" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NoninterestExpense_b9eb1ceb-6771-3351-1281-e8b3cd4f24bc" xlink:to="loc_us-gaap_InformationTechnologyAndDataProcessing_362f9a0f-7f2d-746c-6a38-3815f0270d4b" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OccupancyNet" xlink:label="loc_us-gaap_OccupancyNet_dcfa93d8-21b7-f135-13ea-2a15d58dda33" xlink:type="locator" />
    <link:calculationArc order="3" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NoninterestExpense_b9eb1ceb-6771-3351-1281-e8b3cd4f24bc" xlink:to="loc_us-gaap_OccupancyNet_dcfa93d8-21b7-f135-13ea-2a15d58dda33" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ForeclosedRealEstateExpense" xlink:label="loc_us-gaap_ForeclosedRealEstateExpense_79506dd2-3fe6-218c-a401-af0073b416b0" xlink:type="locator" />
    <link:calculationArc order="4" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NoninterestExpense_b9eb1ceb-6771-3351-1281-e8b3cd4f24bc" xlink:to="loc_us-gaap_ForeclosedRealEstateExpense_79506dd2-3fe6-218c-a401-af0073b416b0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ProfessionalFees" xlink:label="loc_us-gaap_ProfessionalFees_46076b2a-9606-b624-8289-f52fd7fc12d1" xlink:type="locator" />
    <link:calculationArc order="5" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NoninterestExpense_b9eb1ceb-6771-3351-1281-e8b3cd4f24bc" xlink:to="loc_us-gaap_ProfessionalFees_46076b2a-9606-b624-8289-f52fd7fc12d1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AdvertisingExpense" xlink:label="loc_us-gaap_AdvertisingExpense_fb1fb322-643b-e476-bb08-70583a2415d6" xlink:type="locator" />
    <link:calculationArc order="6" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NoninterestExpense_b9eb1ceb-6771-3351-1281-e8b3cd4f24bc" xlink:to="loc_us-gaap_AdvertisingExpense_fb1fb322-643b-e476-bb08-70583a2415d6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AmortizationOfIntangibleAssets" xlink:label="loc_us-gaap_AmortizationOfIntangibleAssets_ae796c5c-1c01-d654-6a3c-3b5dd2c89517" xlink:type="locator" />
    <link:calculationArc order="7" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NoninterestExpense_b9eb1ceb-6771-3351-1281-e8b3cd4f24bc" xlink:to="loc_us-gaap_AmortizationOfIntangibleAssets_ae796c5c-1c01-d654-6a3c-3b5dd2c89517" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_Communication" xlink:label="loc_us-gaap_Communication_39ecff2c-c119-6a40-18fd-315a1ffe47dc" xlink:type="locator" />
    <link:calculationArc order="8" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NoninterestExpense_b9eb1ceb-6771-3351-1281-e8b3cd4f24bc" xlink:to="loc_us-gaap_Communication_39ecff2c-c119-6a40-18fd-315a1ffe47dc" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_GainsLossesOnExtinguishmentOfDebt" xlink:label="loc_us-gaap_GainsLossesOnExtinguishmentOfDebt_3db65903-3171-d63c-a688-532ba00b8108" xlink:type="locator" />
    <link:calculationArc order="9" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NoninterestExpense_b9eb1ceb-6771-3351-1281-e8b3cd4f24bc" xlink:to="loc_us-gaap_GainsLossesOnExtinguishmentOfDebt_3db65903-3171-d63c-a688-532ba00b8108" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_BusinessCombinationAcquisitionRelatedCosts" xlink:label="loc_us-gaap_BusinessCombinationAcquisitionRelatedCosts_b040d8af-154d-5cff-3bde-e86e72dcfffc" xlink:type="locator" />
    <link:calculationArc order="10" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NoninterestExpense_b9eb1ceb-6771-3351-1281-e8b3cd4f24bc" xlink:to="loc_us-gaap_BusinessCombinationAcquisitionRelatedCosts_b040d8af-154d-5cff-3bde-e86e72dcfffc" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherNoninterestExpense" xlink:label="loc_us-gaap_OtherNoninterestExpense_02adc972-ee35-2b4e-07cf-dcb0252789fc" xlink:type="locator" />
    <link:calculationArc order="11" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NoninterestExpense_b9eb1ceb-6771-3351-1281-e8b3cd4f24bc" xlink:to="loc_us-gaap_OtherNoninterestExpense_02adc972-ee35-2b4e-07cf-dcb0252789fc" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeTaxExpenseBenefit" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefit_78b7d85e-8366-fe6d-cb1f-faac5a041b79" xlink:type="locator" />
    <link:calculationArc order="2" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_NetIncomeLoss_641b1cab-a2b3-2e0e-8389-1455ff3f8581" xlink:to="loc_us-gaap_IncomeTaxExpenseBenefit_78b7d85e-8366-fe6d-cb1f-faac5a041b79" xlink:type="arc" />
  </link:calculationLink>
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/DerivativeInstruments" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/DerivativeInstrumentsDetails" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/DerivativeInstrumentsDetails1" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/DerivativeInstrumentsDetails2" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DerivativeLiabilityFairValueOffsetAgainstCollateralNetOfNotSubjectToMasterNettingArrangementPolicyElection" xlink:label="loc_us-gaap_DerivativeLiabilityFairValueOffsetAgainstCollateralNetOfNotSubjectToMasterNettingArrangementPolicyElection_54abb9f9-7d0d-fbcd-6124-89f7392b2d4f" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DerivativeFairValueOfDerivativeLiabilityAmountNotOffsetAgainstCollateral" xlink:label="loc_us-gaap_DerivativeFairValueOfDerivativeLiabilityAmountNotOffsetAgainstCollateral_b101e508-739c-e6e2-2fa2-9fe7226273c7" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DerivativeLiabilityFairValueOffsetAgainstCollateralNetOfNotSubjectToMasterNettingArrangementPolicyElection_54abb9f9-7d0d-fbcd-6124-89f7392b2d4f" xlink:to="loc_us-gaap_DerivativeFairValueOfDerivativeLiabilityAmountNotOffsetAgainstCollateral_b101e508-739c-e6e2-2fa2-9fe7226273c7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DerivativeFairValueOfDerivativeLiability" xlink:label="loc_us-gaap_DerivativeFairValueOfDerivativeLiability_5296452d-3ce9-bd2f-2a62-9643805fc6ab" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DerivativeFairValueOfDerivativeLiabilityAmountNotOffsetAgainstCollateral_b101e508-739c-e6e2-2fa2-9fe7226273c7" xlink:to="loc_us-gaap_DerivativeFairValueOfDerivativeLiability_5296452d-3ce9-bd2f-2a62-9643805fc6ab" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DerivativeLiabilityFairValueGrossAsset" xlink:label="loc_us-gaap_DerivativeLiabilityFairValueGrossAsset_a35dd027-4176-a3b8-92c5-caa74b4d298d" xlink:type="locator" />
    <link:calculationArc order="2" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DerivativeFairValueOfDerivativeLiabilityAmountNotOffsetAgainstCollateral_b101e508-739c-e6e2-2fa2-9fe7226273c7" xlink:to="loc_us-gaap_DerivativeLiabilityFairValueGrossAsset_a35dd027-4176-a3b8-92c5-caa74b4d298d" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DerivativeCollateralRightToReclaimSecurities" xlink:label="loc_us-gaap_DerivativeCollateralRightToReclaimSecurities_fa5ae35c-b4e7-a698-de32-08ea556641ab" xlink:type="locator" />
    <link:calculationArc order="2" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DerivativeLiabilityFairValueOffsetAgainstCollateralNetOfNotSubjectToMasterNettingArrangementPolicyElection_54abb9f9-7d0d-fbcd-6124-89f7392b2d4f" xlink:to="loc_us-gaap_DerivativeCollateralRightToReclaimSecurities_fa5ae35c-b4e7-a698-de32-08ea556641ab" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DerivativeCollateralRightToReclaimCash" xlink:label="loc_us-gaap_DerivativeCollateralRightToReclaimCash_703addb2-f097-e4df-e5c9-7db1ef6b8ddd" xlink:type="locator" />
    <link:calculationArc order="3" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DerivativeLiabilityFairValueOffsetAgainstCollateralNetOfNotSubjectToMasterNettingArrangementPolicyElection_54abb9f9-7d0d-fbcd-6124-89f7392b2d4f" xlink:to="loc_us-gaap_DerivativeCollateralRightToReclaimCash_703addb2-f097-e4df-e5c9-7db1ef6b8ddd" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DerivativeAssetFairValueOffsetAgainstCollateralNetOfNotSubjectToMasterNettingArrangementPolicyElection" xlink:label="loc_us-gaap_DerivativeAssetFairValueOffsetAgainstCollateralNetOfNotSubjectToMasterNettingArrangementPolicyElection_d8f18a08-aef9-264e-aea9-dbef9bc95976" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DerivativeFairValueOfDerivativeAssetAmountNotOffsetAgainstCollateral" xlink:label="loc_us-gaap_DerivativeFairValueOfDerivativeAssetAmountNotOffsetAgainstCollateral_5b305825-95a3-afb7-1b8e-4357b49e2ec7" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DerivativeAssetFairValueOffsetAgainstCollateralNetOfNotSubjectToMasterNettingArrangementPolicyElection_d8f18a08-aef9-264e-aea9-dbef9bc95976" xlink:to="loc_us-gaap_DerivativeFairValueOfDerivativeAssetAmountNotOffsetAgainstCollateral_5b305825-95a3-afb7-1b8e-4357b49e2ec7" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DerivativeFairValueOfDerivativeAsset" xlink:label="loc_us-gaap_DerivativeFairValueOfDerivativeAsset_62eb8c59-8348-bd48-683f-a9f1d164ff20" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DerivativeFairValueOfDerivativeAssetAmountNotOffsetAgainstCollateral_5b305825-95a3-afb7-1b8e-4357b49e2ec7" xlink:to="loc_us-gaap_DerivativeFairValueOfDerivativeAsset_62eb8c59-8348-bd48-683f-a9f1d164ff20" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DerivativeAssetFairValueGrossLiability" xlink:label="loc_us-gaap_DerivativeAssetFairValueGrossLiability_632d52c4-5035-e390-8263-9001adf1afa1" xlink:type="locator" />
    <link:calculationArc order="2" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DerivativeFairValueOfDerivativeAssetAmountNotOffsetAgainstCollateral_5b305825-95a3-afb7-1b8e-4357b49e2ec7" xlink:to="loc_us-gaap_DerivativeAssetFairValueGrossLiability_632d52c4-5035-e390-8263-9001adf1afa1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DerivativeCollateralObligationToReturnSecurities" xlink:label="loc_us-gaap_DerivativeCollateralObligationToReturnSecurities_d215614e-6e5d-ffec-41c2-1f19be1f15e4" xlink:type="locator" />
    <link:calculationArc order="2" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DerivativeAssetFairValueOffsetAgainstCollateralNetOfNotSubjectToMasterNettingArrangementPolicyElection_d8f18a08-aef9-264e-aea9-dbef9bc95976" xlink:to="loc_us-gaap_DerivativeCollateralObligationToReturnSecurities_d215614e-6e5d-ffec-41c2-1f19be1f15e4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DerivativeCollateralObligationToReturnCash" xlink:label="loc_us-gaap_DerivativeCollateralObligationToReturnCash_8060d50a-80f9-7a72-a6c9-845ee11dfd93" xlink:type="locator" />
    <link:calculationArc order="3" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DerivativeAssetFairValueOffsetAgainstCollateralNetOfNotSubjectToMasterNettingArrangementPolicyElection_d8f18a08-aef9-264e-aea9-dbef9bc95976" xlink:to="loc_us-gaap_DerivativeCollateralObligationToReturnCash_8060d50a-80f9-7a72-a6c9-845ee11dfd93" xlink:type="arc" />
  </link:calculationLink>
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/DerivativeInstrumentsDetailsTextual" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/DerivativeInstrumentsTables" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/DocumentAndEntityInformation" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/EmployeeBenefitAndDeferredCompensationPlans" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/EmployeeBenefitAndDeferredCompensationPlansDetails1" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DefinedBenefitPlanNetPeriodicBenefitCost" xlink:label="loc_us-gaap_DefinedBenefitPlanNetPeriodicBenefitCost_bae25320-9d69-b27b-4684-0b60368d617f" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DefinedBenefitPlanServiceCost" xlink:label="loc_us-gaap_DefinedBenefitPlanServiceCost_89ad3af5-a7a9-a0b6-3ed0-1824210c7a90" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DefinedBenefitPlanNetPeriodicBenefitCost_bae25320-9d69-b27b-4684-0b60368d617f" xlink:to="loc_us-gaap_DefinedBenefitPlanServiceCost_89ad3af5-a7a9-a0b6-3ed0-1824210c7a90" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DefinedBenefitPlanInterestCost" xlink:label="loc_us-gaap_DefinedBenefitPlanInterestCost_50406d00-3746-2e05-3a50-4b2bf529ff14" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DefinedBenefitPlanNetPeriodicBenefitCost_bae25320-9d69-b27b-4684-0b60368d617f" xlink:to="loc_us-gaap_DefinedBenefitPlanInterestCost_50406d00-3746-2e05-3a50-4b2bf529ff14" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DefinedBenefitPlanExpectedReturnOnPlanAssets" xlink:label="loc_us-gaap_DefinedBenefitPlanExpectedReturnOnPlanAssets_053c4475-6836-cf00-1abe-b15f58110eab" xlink:type="locator" />
    <link:calculationArc order="3" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DefinedBenefitPlanNetPeriodicBenefitCost_bae25320-9d69-b27b-4684-0b60368d617f" xlink:to="loc_us-gaap_DefinedBenefitPlanExpectedReturnOnPlanAssets_053c4475-6836-cf00-1abe-b15f58110eab" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DefinedBenefitPlanAmortizationOfGainsLosses" xlink:label="loc_us-gaap_DefinedBenefitPlanAmortizationOfGainsLosses_b2e93b1c-a313-bd95-39dd-1f9d9938b2e9" xlink:type="locator" />
    <link:calculationArc order="4" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DefinedBenefitPlanNetPeriodicBenefitCost_bae25320-9d69-b27b-4684-0b60368d617f" xlink:to="loc_us-gaap_DefinedBenefitPlanAmortizationOfGainsLosses_b2e93b1c-a313-bd95-39dd-1f9d9938b2e9" xlink:type="arc" />
  </link:calculationLink>
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/EmployeeBenefitAndDeferredCompensationPlansDetails2" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/EmployeeBenefitAndDeferredCompensationPlansDetails3" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/EmployeeBenefitAndDeferredCompensationPlansDetailsTextual" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/EmployeeBenefitAndDeferredCompensationPlansTables" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/FairValueMeasurements" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/FairValueMeasurementsDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LiabilitiesFairValueDisclosure" xlink:label="loc_us-gaap_LiabilitiesFairValueDisclosure_61bb41c2-5e2c-2804-d184-f566af2acbb1" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DerivativeLiabilities" xlink:label="loc_us-gaap_DerivativeLiabilities_a3ccd28b-d904-f2d6-d218-02006f748e50" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LiabilitiesFairValueDisclosure_61bb41c2-5e2c-2804-d184-f566af2acbb1" xlink:to="loc_us-gaap_DerivativeLiabilities_a3ccd28b-d904-f2d6-d218-02006f748e50" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AssetsFairValueDisclosure" xlink:label="loc_us-gaap_AssetsFairValueDisclosure_b86af6cd-ef38-8a02-5297-9329a99c960d" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_MortgagesHeldForSaleFairValueDisclosure" xlink:label="loc_us-gaap_MortgagesHeldForSaleFairValueDisclosure_00fff42f-ba49-6993-723e-7c4718f98e2e" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsFairValueDisclosure_b86af6cd-ef38-8a02-5297-9329a99c960d" xlink:to="loc_us-gaap_MortgagesHeldForSaleFairValueDisclosure_00fff42f-ba49-6993-723e-7c4718f98e2e" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DerivativeAssets" xlink:label="loc_us-gaap_DerivativeAssets_990d24f7-bf09-089d-4b5d-4490e079db44" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsFairValueDisclosure_b86af6cd-ef38-8a02-5297-9329a99c960d" xlink:to="loc_us-gaap_DerivativeAssets_990d24f7-bf09-089d-4b5d-4490e079db44" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AvailableForSaleSecurities" xlink:label="loc_us-gaap_AvailableForSaleSecurities_d444402b-921b-e0fa-119c-908ab66850af" xlink:type="locator" />
    <link:calculationArc order="3" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsFairValueDisclosure_b86af6cd-ef38-8a02-5297-9329a99c960d" xlink:to="loc_us-gaap_AvailableForSaleSecurities_d444402b-921b-e0fa-119c-908ab66850af" xlink:type="arc" />
  </link:calculationLink>
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/FairValueMeasurementsDetails1" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/FairValueMeasurementsDetails2" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/FairValueMeasurementsDetails3" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AssetsFairValueDisclosureNonrecurring" xlink:label="loc_us-gaap_AssetsFairValueDisclosureNonrecurring_d99e2c5b-72f7-4711-958e-0a57181374cc" xlink:type="locator" />
    <link:loc xlink:href="rnst-20170630.xsd#rnst_ImpairedLoansMeasuredAtFairValueOnNonrecurringBasis" xlink:label="loc_rnst_ImpairedLoansMeasuredAtFairValueOnNonrecurringBasis_1b80ba5b-a908-8dea-ff9a-a767af27d8b1" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsFairValueDisclosureNonrecurring_d99e2c5b-72f7-4711-958e-0a57181374cc" xlink:to="loc_rnst_ImpairedLoansMeasuredAtFairValueOnNonrecurringBasis_1b80ba5b-a908-8dea-ff9a-a767af27d8b1" xlink:type="arc" />
    <link:loc xlink:href="rnst-20170630.xsd#rnst_OtherRealEstateOwnedMeasuredAtFairValueOnNonRecurringBasis" xlink:label="loc_rnst_OtherRealEstateOwnedMeasuredAtFairValueOnNonRecurringBasis_3edfd107-e3ec-ac10-e88f-a767adfcfab4" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsFairValueDisclosureNonrecurring_d99e2c5b-72f7-4711-958e-0a57181374cc" xlink:to="loc_rnst_OtherRealEstateOwnedMeasuredAtFairValueOnNonRecurringBasis_3edfd107-e3ec-ac10-e88f-a767adfcfab4" xlink:type="arc" />
    <link:loc xlink:href="rnst-20170630.xsd#rnst_MortgageServicingRightsFairValueDisclosure" xlink:label="loc_rnst_MortgageServicingRightsFairValueDisclosure_1ec0fedb-b981-c18d-dd4f-a767af0bedad" xlink:type="locator" />
    <link:calculationArc order="3" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AssetsFairValueDisclosureNonrecurring_d99e2c5b-72f7-4711-958e-0a57181374cc" xlink:to="loc_rnst_MortgageServicingRightsFairValueDisclosure_1ec0fedb-b981-c18d-dd4f-a767af0bedad" xlink:type="arc" />
  </link:calculationLink>
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/FairValueMeasurementsDetails4" xlink:type="extended">
    <link:loc xlink:href="rnst-20170630.xsd#rnst_OtherRealEstateOwnedNonCoveredFairValue" xlink:label="loc_rnst_OtherRealEstateOwnedNonCoveredFairValue_4a6af620-9a99-8712-b25d-a767aeed0454" xlink:type="locator" />
    <link:loc xlink:href="rnst-20170630.xsd#rnst_OtherRealEstateNonCoveredCarryingAmount" xlink:label="loc_rnst_OtherRealEstateNonCoveredCarryingAmount_71dbbafd-7c5f-5f39-ff17-a767ae41f5a4" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_rnst_OtherRealEstateOwnedNonCoveredFairValue_4a6af620-9a99-8712-b25d-a767aeed0454" xlink:to="loc_rnst_OtherRealEstateNonCoveredCarryingAmount_71dbbafd-7c5f-5f39-ff17-a767ae41f5a4" xlink:type="arc" />
    <link:loc xlink:href="rnst-20170630.xsd#rnst_OtherRealEstateNonCoveredImpairmentRecognized" xlink:label="loc_rnst_OtherRealEstateNonCoveredImpairmentRecognized_ae73b913-507f-b34d-f6ad-a767acb9a277" xlink:type="locator" />
    <link:calculationArc order="2" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_rnst_OtherRealEstateOwnedNonCoveredFairValue_4a6af620-9a99-8712-b25d-a767aeed0454" xlink:to="loc_rnst_OtherRealEstateNonCoveredImpairmentRecognized_ae73b913-507f-b34d-f6ad-a767acb9a277" xlink:type="arc" />
  </link:calculationLink>
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/FairValueMeasurementsDetails5" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/FairValueMeasurementsDetails6" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/FairValueMeasurementsDetails7" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/FairValueMeasurementsDetailsTextual" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/FairValueMeasurementsTables" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/GoodwillAndOtherIntangibleAssets" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/GoodwillAndOtherIntangibleAssetsDetails" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/GoodwillAndOtherIntangibleAssetsDetails1" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsNet" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsNet_49187b45-82fd-7060-b114-79ff249a4331" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsGross" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsGross_5d62e128-f1a1-954f-82e2-1936cb67d793" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_49187b45-82fd-7060-b114-79ff249a4331" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsGross_5d62e128-f1a1-954f-82e2-1936cb67d793" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization" xlink:label="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_c3ed8a56-abe0-6418-c541-e6b647d6318a" xlink:type="locator" />
    <link:calculationArc order="2" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_FiniteLivedIntangibleAssetsNet_49187b45-82fd-7060-b114-79ff249a4331" xlink:to="loc_us-gaap_FiniteLivedIntangibleAssetsAccumulatedAmortization_c3ed8a56-abe0-6418-c541-e6b647d6318a" xlink:type="arc" />
  </link:calculationLink>
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/GoodwillAndOtherIntangibleAssetsDetails2" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/GoodwillAndOtherIntangibleAssetsDetails3" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/GoodwillAndOtherIntangibleAssetsTables" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/IncomeTaxes" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/IncomeTaxesDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DeferredTaxAssetsLiabilitiesNet" xlink:label="loc_us-gaap_DeferredTaxAssetsLiabilitiesNet_b361a033-37cf-a2bc-6e1f-0297b90aa5a9" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DeferredTaxAssetsNet" xlink:label="loc_us-gaap_DeferredTaxAssetsNet_d74724c2-178d-7f3f-8e86-5f5ba690672c" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsLiabilitiesNet_b361a033-37cf-a2bc-6e1f-0297b90aa5a9" xlink:to="loc_us-gaap_DeferredTaxAssetsNet_d74724c2-178d-7f3f-8e86-5f5ba690672c" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsProvisionForLoanLosses" xlink:label="loc_us-gaap_DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsProvisionForLoanLosses_34825a29-f08a-602c-93b3-eaaa9098ff88" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsNet_d74724c2-178d-7f3f-8e86-5f5ba690672c" xlink:to="loc_us-gaap_DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsProvisionForLoanLosses_34825a29-f08a-602c-93b3-eaaa9098ff88" xlink:type="arc" />
    <link:loc xlink:href="rnst-20170630.xsd#rnst_DeferredTaxAssetsPurchaseAccountingAdjustments" xlink:label="loc_rnst_DeferredTaxAssetsPurchaseAccountingAdjustments_bddd8b72-092b-7122-7244-a767adf3889b" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsNet_d74724c2-178d-7f3f-8e86-5f5ba690672c" xlink:to="loc_rnst_DeferredTaxAssetsPurchaseAccountingAdjustments_bddd8b72-092b-7122-7244-a767adf3889b" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost" xlink:label="loc_us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost_f7e9e6da-5d57-5f97-5d33-52f319506ef0" xlink:type="locator" />
    <link:calculationArc order="3" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsNet_d74724c2-178d-7f3f-8e86-5f5ba690672c" xlink:to="loc_us-gaap_DeferredTaxAssetsTaxDeferredExpenseCompensationAndBenefitsShareBasedCompensationCost_f7e9e6da-5d57-5f97-5d33-52f319506ef0" xlink:type="arc" />
    <link:loc xlink:href="rnst-20170630.xsd#rnst_DeferredTaxAssetsSecurities" xlink:label="loc_rnst_DeferredTaxAssetsSecurities_623211c0-31f0-5ab9-a2ec-a767ada3d417" xlink:type="locator" />
    <link:calculationArc order="4" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsNet_d74724c2-178d-7f3f-8e86-5f5ba690672c" xlink:to="loc_rnst_DeferredTaxAssetsSecurities_623211c0-31f0-5ab9-a2ec-a767ada3d417" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DeferredTaxAssetsUnrealizedLossesOnAvailableforSaleSecuritiesGross" xlink:label="loc_us-gaap_DeferredTaxAssetsUnrealizedLossesOnAvailableforSaleSecuritiesGross_44d5c8ed-b97a-92e4-6956-e1116b0beb88" xlink:type="locator" />
    <link:calculationArc order="5" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsNet_d74724c2-178d-7f3f-8e86-5f5ba690672c" xlink:to="loc_us-gaap_DeferredTaxAssetsUnrealizedLossesOnAvailableforSaleSecuritiesGross_44d5c8ed-b97a-92e4-6956-e1116b0beb88" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsImpairmentLosses" xlink:label="loc_us-gaap_DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsImpairmentLosses_5ca256f2-1415-8adb-96f6-f0a05f6770d0" xlink:type="locator" />
    <link:calculationArc order="6" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsNet_d74724c2-178d-7f3f-8e86-5f5ba690672c" xlink:to="loc_us-gaap_DeferredTaxAssetsTaxDeferredExpenseReservesAndAccrualsImpairmentLosses_5ca256f2-1415-8adb-96f6-f0a05f6770d0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DeferredTaxAssetsOperatingLossCarryforwardsStateAndLocal" xlink:label="loc_us-gaap_DeferredTaxAssetsOperatingLossCarryforwardsStateAndLocal_a9e69e90-362c-096d-424d-dfd51b492a2e" xlink:type="locator" />
    <link:calculationArc order="7" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsNet_d74724c2-178d-7f3f-8e86-5f5ba690672c" xlink:to="loc_us-gaap_DeferredTaxAssetsOperatingLossCarryforwardsStateAndLocal_a9e69e90-362c-096d-424d-dfd51b492a2e" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DeferredTaxAssetsGoodwillAndIntangibleAssets" xlink:label="loc_us-gaap_DeferredTaxAssetsGoodwillAndIntangibleAssets_e1d12118-f49a-bc63-5339-100c22e4468d" xlink:type="locator" />
    <link:calculationArc order="8" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsNet_d74724c2-178d-7f3f-8e86-5f5ba690672c" xlink:to="loc_us-gaap_DeferredTaxAssetsGoodwillAndIntangibleAssets_e1d12118-f49a-bc63-5339-100c22e4468d" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DeferredTaxAssetsOther" xlink:label="loc_us-gaap_DeferredTaxAssetsOther_91623f44-5f42-408a-f7b7-7a4698afab83" xlink:type="locator" />
    <link:calculationArc order="9" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsNet_d74724c2-178d-7f3f-8e86-5f5ba690672c" xlink:to="loc_us-gaap_DeferredTaxAssetsOther_91623f44-5f42-408a-f7b7-7a4698afab83" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DeferredIncomeTaxLiabilities" xlink:label="loc_us-gaap_DeferredIncomeTaxLiabilities_bbf9fd06-b461-3f65-8882-6e322d99a60b" xlink:type="locator" />
    <link:calculationArc order="2" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredTaxAssetsLiabilitiesNet_b361a033-37cf-a2bc-6e1f-0297b90aa5a9" xlink:to="loc_us-gaap_DeferredIncomeTaxLiabilities_bbf9fd06-b461-3f65-8882-6e322d99a60b" xlink:type="arc" />
    <link:loc xlink:href="rnst-20170630.xsd#rnst_DeferredTaxLiabilityBasisDifferenceInAcquiredAssets" xlink:label="loc_rnst_DeferredTaxLiabilityBasisDifferenceInAcquiredAssets_32638244-d7ce-aed6-91ed-a767ae108f71" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredIncomeTaxLiabilities_bbf9fd06-b461-3f65-8882-6e322d99a60b" xlink:to="loc_rnst_DeferredTaxLiabilityBasisDifferenceInAcquiredAssets_32638244-d7ce-aed6-91ed-a767ae108f71" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DeferredTaxLiabilitiesInvestments" xlink:label="loc_us-gaap_DeferredTaxLiabilitiesInvestments_11fe7ea9-3f55-290e-87ec-27a8ad4ddaee" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredIncomeTaxLiabilities_bbf9fd06-b461-3f65-8882-6e322d99a60b" xlink:to="loc_us-gaap_DeferredTaxLiabilitiesInvestments_11fe7ea9-3f55-290e-87ec-27a8ad4ddaee" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DeferredTaxLiabilitiesGoodwillAndIntangibleAssetsIntangibleAssets" xlink:label="loc_us-gaap_DeferredTaxLiabilitiesGoodwillAndIntangibleAssetsIntangibleAssets_d1de4f5a-e70f-c355-7179-89a9064c7b88" xlink:type="locator" />
    <link:calculationArc order="3" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredIncomeTaxLiabilities_bbf9fd06-b461-3f65-8882-6e322d99a60b" xlink:to="loc_us-gaap_DeferredTaxLiabilitiesGoodwillAndIntangibleAssetsIntangibleAssets_d1de4f5a-e70f-c355-7179-89a9064c7b88" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DeferredTaxLiabilitiesPropertyPlantAndEquipment" xlink:label="loc_us-gaap_DeferredTaxLiabilitiesPropertyPlantAndEquipment_dde5eeca-2b71-60e2-a05c-fb2f2f5703af" xlink:type="locator" />
    <link:calculationArc order="4" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredIncomeTaxLiabilities_bbf9fd06-b461-3f65-8882-6e322d99a60b" xlink:to="loc_us-gaap_DeferredTaxLiabilitiesPropertyPlantAndEquipment_dde5eeca-2b71-60e2-a05c-fb2f2f5703af" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DeferredTaxLiabilitiesMortgageServicingRights" xlink:label="loc_us-gaap_DeferredTaxLiabilitiesMortgageServicingRights_d9ed2b14-8d75-ee39-ab71-3148c0bbe627" xlink:type="locator" />
    <link:calculationArc order="5" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredIncomeTaxLiabilities_bbf9fd06-b461-3f65-8882-6e322d99a60b" xlink:to="loc_us-gaap_DeferredTaxLiabilitiesMortgageServicingRights_d9ed2b14-8d75-ee39-ab71-3148c0bbe627" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DeferredTaxLiabilitiesFinancingArrangements" xlink:label="loc_us-gaap_DeferredTaxLiabilitiesFinancingArrangements_e5aff4c4-dcfd-57b9-9f7d-cdee77a4045f" xlink:type="locator" />
    <link:calculationArc order="6" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredIncomeTaxLiabilities_bbf9fd06-b461-3f65-8882-6e322d99a60b" xlink:to="loc_us-gaap_DeferredTaxLiabilitiesFinancingArrangements_e5aff4c4-dcfd-57b9-9f7d-cdee77a4045f" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_DeferredTaxLiabilitiesOther" xlink:label="loc_us-gaap_DeferredTaxLiabilitiesOther_40c7d4a7-f1a1-0c55-497e-f9a3bb09604c" xlink:type="locator" />
    <link:calculationArc order="7" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_DeferredIncomeTaxLiabilities_bbf9fd06-b461-3f65-8882-6e322d99a60b" xlink:to="loc_us-gaap_DeferredTaxLiabilitiesOther_40c7d4a7-f1a1-0c55-497e-f9a3bb09604c" xlink:type="arc" />
  </link:calculationLink>
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/IncomeTaxesDetailsTextual" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/IncomeTaxesTables" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/InvestmentsInQualifiedAffordableHousingProjects" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/InvestmentsInQualifiedAffordableHousingProjectsDetails" xlink:type="extended">
    <link:loc xlink:href="rnst-20170630.xsd#rnst_AffordableHousingTaxCreditsandOtherBenefitsNetofAmortization" xlink:label="loc_rnst_AffordableHousingTaxCreditsandOtherBenefitsNetofAmortization_3856d6e9-f3f6-0862-bcf7-a767ae65d37f" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AmortizationMethodQualifiedAffordableHousingProjectInvestmentsAmortization" xlink:label="loc_us-gaap_AmortizationMethodQualifiedAffordableHousingProjectInvestmentsAmortization_905ba0d2-11e4-a5d4-1d81-bfd3f4389761" xlink:type="locator" />
    <link:calculationArc order="1" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_rnst_AffordableHousingTaxCreditsandOtherBenefitsNetofAmortization_3856d6e9-f3f6-0862-bcf7-a767ae65d37f" xlink:to="loc_us-gaap_AmortizationMethodQualifiedAffordableHousingProjectInvestmentsAmortization_905ba0d2-11e4-a5d4-1d81-bfd3f4389761" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AffordableHousingTaxCreditsAndOtherTaxBenefitsAmount" xlink:label="loc_us-gaap_AffordableHousingTaxCreditsAndOtherTaxBenefitsAmount_293236c8-fd90-38e7-1919-3358f861435c" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_rnst_AffordableHousingTaxCreditsandOtherBenefitsNetofAmortization_3856d6e9-f3f6-0862-bcf7-a767ae65d37f" xlink:to="loc_us-gaap_AffordableHousingTaxCreditsAndOtherTaxBenefitsAmount_293236c8-fd90-38e7-1919-3358f861435c" xlink:type="arc" />
  </link:calculationLink>
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/InvestmentsInQualifiedAffordableHousingProjectsTables" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/MergersAndAcquisitions" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/MergersAndAcquisitionsDetailsTextual" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/MortgageServicingRights" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/MortgageServicingRightsDetails" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/MortgageServicingRightsDetails1" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/MortgageServicingRightsDetailsTextual" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/MortgageServicingRightsTables" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/NetIncomePerCommonShare" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/NetIncomePerCommonShareDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding" xlink:label="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_223fd9c8-68e8-e433-7c40-f98b238e79de" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingBasic" xlink:label="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_86e61cf2-b7b2-e230-65f1-5a2b152f3a30" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_223fd9c8-68e8-e433-7c40-f98b238e79de" xlink:to="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_86e61cf2-b7b2-e230-65f1-5a2b152f3a30" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements" xlink:label="loc_us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements_cee10fe8-a4bb-491c-22f6-69a723d6a718" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_223fd9c8-68e8-e433-7c40-f98b238e79de" xlink:to="loc_us-gaap_IncrementalCommonSharesAttributableToShareBasedPaymentArrangements_cee10fe8-a4bb-491c-22f6-69a723d6a718" xlink:type="arc" />
  </link:calculationLink>
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/NetIncomePerCommonShareDetails1" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/NetIncomePerCommonShareTables" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/NonPurchasedLoans" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/NonPurchasedLoansDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LoansAndLeasesReceivableNetOfDeferredIncome" xlink:label="loc_us-gaap_LoansAndLeasesReceivableNetOfDeferredIncome_99b7c0b8-78d1-c66a-eb0a-fb20f225718b" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LoansAndLeasesReceivableDeferredIncome" xlink:label="loc_us-gaap_LoansAndLeasesReceivableDeferredIncome_c63fd2ea-e262-a927-cba2-c8bdeff9a737" xlink:type="locator" />
    <link:calculationArc order="1" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LoansAndLeasesReceivableNetOfDeferredIncome_99b7c0b8-78d1-c66a-eb0a-fb20f225718b" xlink:to="loc_us-gaap_LoansAndLeasesReceivableDeferredIncome_c63fd2ea-e262-a927-cba2-c8bdeff9a737" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LoansAndLeasesReceivableGrossCarryingAmount" xlink:label="loc_us-gaap_LoansAndLeasesReceivableGrossCarryingAmount_d4ff86fc-d3e8-a070-89c1-3818078e0b14" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LoansAndLeasesReceivableNetOfDeferredIncome_99b7c0b8-78d1-c66a-eb0a-fb20f225718b" xlink:to="loc_us-gaap_LoansAndLeasesReceivableGrossCarryingAmount_d4ff86fc-d3e8-a070-89c1-3818078e0b14" xlink:type="arc" />
  </link:calculationLink>
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/NonPurchasedLoansDetails1" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LoansAndLeasesReceivableNetOfDeferredIncome" xlink:label="loc_us-gaap_LoansAndLeasesReceivableNetOfDeferredIncome_99b7c0b8-78d1-c66a-eb0a-fb20f225718b" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FinancingReceivableRecordedInvestmentPastDue" xlink:label="loc_us-gaap_FinancingReceivableRecordedInvestmentPastDue_a2853db1-cebd-a17c-f6ff-3ade2a726584" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LoansAndLeasesReceivableNetOfDeferredIncome_99b7c0b8-78d1-c66a-eb0a-fb20f225718b" xlink:to="loc_us-gaap_FinancingReceivableRecordedInvestmentPastDue_a2853db1-cebd-a17c-f6ff-3ade2a726584" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_FinancingReceivableRecordedInvestmentCurrent" xlink:label="loc_us-gaap_FinancingReceivableRecordedInvestmentCurrent_38a9b0f0-99cf-7bf1-a2e9-09df10077c91" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LoansAndLeasesReceivableNetOfDeferredIncome_99b7c0b8-78d1-c66a-eb0a-fb20f225718b" xlink:to="loc_us-gaap_FinancingReceivableRecordedInvestmentCurrent_38a9b0f0-99cf-7bf1-a2e9-09df10077c91" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_LoansAndLeasesReceivableGrossCarryingAmount" xlink:label="loc_us-gaap_LoansAndLeasesReceivableGrossCarryingAmount_d4ff86fc-d3e8-a070-89c1-3818078e0b14" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LoansAndLeasesReceivableGrossCarryingAmount_d4ff86fc-d3e8-a070-89c1-3818078e0b14" xlink:to="loc_us-gaap_FinancingReceivableRecordedInvestmentPastDue_a2853db1-cebd-a17c-f6ff-3ade2a726584" xlink:type="arc" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_LoansAndLeasesReceivableGrossCarryingAmount_d4ff86fc-d3e8-a070-89c1-3818078e0b14" xlink:to="loc_us-gaap_FinancingReceivableRecordedInvestmentCurrent_38a9b0f0-99cf-7bf1-a2e9-09df10077c91" xlink:type="arc" />
  </link:calculationLink>
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/NonPurchasedLoansDetails2" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ImpairedFinancingReceivableRecordedInvestment" xlink:label="loc_us-gaap_ImpairedFinancingReceivableRecordedInvestment_15a0be6e-6399-7796-5a21-351d6bdf38c0" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ImpairedFinancingReceivableWithRelatedAllowanceRecordedInvestment" xlink:label="loc_us-gaap_ImpairedFinancingReceivableWithRelatedAllowanceRecordedInvestment_be7a8a02-ce08-c29c-f736-c19574a96602" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_ImpairedFinancingReceivableRecordedInvestment_15a0be6e-6399-7796-5a21-351d6bdf38c0" xlink:to="loc_us-gaap_ImpairedFinancingReceivableWithRelatedAllowanceRecordedInvestment_be7a8a02-ce08-c29c-f736-c19574a96602" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ImpairedFinancingReceivableWithNoRelatedAllowanceRecordedInvestment" xlink:label="loc_us-gaap_ImpairedFinancingReceivableWithNoRelatedAllowanceRecordedInvestment_cc47adb0-1bde-8a7e-893c-e21dfd67fbcc" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_ImpairedFinancingReceivableRecordedInvestment_15a0be6e-6399-7796-5a21-351d6bdf38c0" xlink:to="loc_us-gaap_ImpairedFinancingReceivableWithNoRelatedAllowanceRecordedInvestment_cc47adb0-1bde-8a7e-893c-e21dfd67fbcc" xlink:type="arc" />
  </link:calculationLink>
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/NonPurchasedLoansDetails3" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/NonPurchasedLoansDetails4" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/NonPurchasedLoansDetails5" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/NonPurchasedLoansDetails6" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/NonPurchasedLoansDetails7" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/NonPurchasedLoansDetailsTextual" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/NonPurchasedLoansTables" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/OtherComprehensiveIncomeLoss" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/OtherComprehensiveIncomeLossDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossBeforeTax" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossBeforeTax_27a35677-5e4b-23be-d135-9b2a303ead30" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossBeforeReclassificationsBeforeTax" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossBeforeReclassificationsBeforeTax_b674c110-7812-0dc8-8cc2-4f91aba944fc" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossBeforeTax_27a35677-5e4b-23be-d135-9b2a303ead30" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossBeforeReclassificationsBeforeTax_b674c110-7812-0dc8-8cc2-4f91aba944fc" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ReclassificationFromAccumulatedOtherComprehensiveIncomeCurrentPeriodBeforeTax" xlink:label="loc_us-gaap_ReclassificationFromAccumulatedOtherComprehensiveIncomeCurrentPeriodBeforeTax_7ca9750b-5cc8-aa85-3585-a06b9895ebbb" xlink:type="locator" />
    <link:calculationArc order="2" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossBeforeTax_27a35677-5e4b-23be-d135-9b2a303ead30" xlink:to="loc_us-gaap_ReclassificationFromAccumulatedOtherComprehensiveIncomeCurrentPeriodBeforeTax_7ca9750b-5cc8-aa85-3585-a06b9895ebbb" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossTax" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossTax_fd5fd01d-ccd5-2fe2-e9ee-a9a84a842378" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossBeforeReclassificationsTax" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossBeforeReclassificationsTax_84c98a8a-c01f-0f38-3ce9-e36c906305cf" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossTax_fd5fd01d-ccd5-2fe2-e9ee-a9a84a842378" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossBeforeReclassificationsTax_84c98a8a-c01f-0f38-3ce9-e36c906305cf" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ReclassificationFromAociCurrentPeriodTax" xlink:label="loc_us-gaap_ReclassificationFromAociCurrentPeriodTax_061de37f-a226-2a79-ad31-92c9dc51a118" xlink:type="locator" />
    <link:calculationArc order="2" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossTax_fd5fd01d-ccd5-2fe2-e9ee-a9a84a842378" xlink:to="loc_us-gaap_ReclassificationFromAociCurrentPeriodTax_061de37f-a226-2a79-ad31-92c9dc51a118" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTax" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTax_2a6e77d2-a694-61f8-1c68-085fd849c780" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherComprehensiveIncomeLossBeforeReclassificationsNetOfTax" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossBeforeReclassificationsNetOfTax_80870f71-876e-eaaa-f0a4-8338d8e9798b" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTax_2a6e77d2-a694-61f8-1c68-085fd849c780" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossBeforeReclassificationsNetOfTax_80870f71-876e-eaaa-f0a4-8338d8e9798b" xlink:type="arc" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossBeforeReclassificationsNetOfTax_80870f71-876e-eaaa-f0a4-8338d8e9798b" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossBeforeReclassificationsBeforeTax_b674c110-7812-0dc8-8cc2-4f91aba944fc" xlink:type="arc" />
    <link:calculationArc order="2" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossBeforeReclassificationsNetOfTax_80870f71-876e-eaaa-f0a4-8338d8e9798b" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossBeforeReclassificationsTax_84c98a8a-c01f-0f38-3ce9-e36c906305cf" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ReclassificationFromAccumulatedOtherComprehensiveIncomeCurrentPeriodNetOfTax" xlink:label="loc_us-gaap_ReclassificationFromAccumulatedOtherComprehensiveIncomeCurrentPeriodNetOfTax_c1323577-e536-9051-1401-d064e7621fd6" xlink:type="locator" />
    <link:calculationArc order="2" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTax_2a6e77d2-a694-61f8-1c68-085fd849c780" xlink:to="loc_us-gaap_ReclassificationFromAccumulatedOtherComprehensiveIncomeCurrentPeriodNetOfTax_c1323577-e536-9051-1401-d064e7621fd6" xlink:type="arc" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_ReclassificationFromAccumulatedOtherComprehensiveIncomeCurrentPeriodNetOfTax_c1323577-e536-9051-1401-d064e7621fd6" xlink:to="loc_us-gaap_ReclassificationFromAccumulatedOtherComprehensiveIncomeCurrentPeriodBeforeTax_7ca9750b-5cc8-aa85-3585-a06b9895ebbb" xlink:type="arc" />
    <link:calculationArc order="2" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_ReclassificationFromAccumulatedOtherComprehensiveIncomeCurrentPeriodNetOfTax_c1323577-e536-9051-1401-d064e7621fd6" xlink:to="loc_us-gaap_ReclassificationFromAociCurrentPeriodTax_061de37f-a226-2a79-ad31-92c9dc51a118" xlink:type="arc" />
  </link:calculationLink>
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/OtherComprehensiveIncomeLossDetails1" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_04f0961a-a0bc-88cf-6658-3f950da4a458" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax_e38d562c-e1dd-d525-b8c6-f86d8a100397" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_04f0961a-a0bc-88cf-6658-3f950da4a458" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossAvailableForSaleSecuritiesAdjustmentNetOfTax_e38d562c-e1dd-d525-b8c6-f86d8a100397" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossOtherThanTemporaryImpairmentNotCreditLossNetOfTaxDebtSecurities" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossOtherThanTemporaryImpairmentNotCreditLossNetOfTaxDebtSecurities_e76a8d65-024b-c67a-b3d7-0b363c5beee3" xlink:type="locator" />
    <link:calculationArc order="2" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_04f0961a-a0bc-88cf-6658-3f950da4a458" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossOtherThanTemporaryImpairmentNotCreditLossNetOfTaxDebtSecurities_e76a8d65-024b-c67a-b3d7-0b363c5beee3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossCumulativeChangesInNetGainLossFromCashFlowHedgesEffectNetOfTax" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossCumulativeChangesInNetGainLossFromCashFlowHedgesEffectNetOfTax_e29c472a-465e-2c89-1ec3-faa641b16e0c" xlink:type="locator" />
    <link:calculationArc order="3" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_04f0961a-a0bc-88cf-6658-3f950da4a458" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossCumulativeChangesInNetGainLossFromCashFlowHedgesEffectNetOfTax_e29c472a-465e-2c89-1ec3-faa641b16e0c" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossDefinedBenefitPensionAndOtherPostretirementPlansNetOfTax" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossDefinedBenefitPensionAndOtherPostretirementPlansNetOfTax_ac65944e-d0a3-7081-a0ad-366dc25783e8" xlink:type="locator" />
    <link:calculationArc order="4" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_04f0961a-a0bc-88cf-6658-3f950da4a458" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossDefinedBenefitPensionAndOtherPostretirementPlansNetOfTax_ac65944e-d0a3-7081-a0ad-366dc25783e8" xlink:type="arc" />
  </link:calculationLink>
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/OtherComprehensiveIncomeLossTables" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/OtherRealEstateOwned" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/OtherRealEstateOwnedDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherRealEstateAndForeclosedAssets" xlink:label="loc_us-gaap_OtherRealEstateAndForeclosedAssets_981e6fe7-fa32-4b68-a956-d14acea056c4" xlink:type="locator" />
    <link:loc xlink:href="rnst-20170630.xsd#rnst_CoveredUnderLossShareAgreementsOtherRealEstateOwnedAndRepossessions" xlink:label="loc_rnst_CoveredUnderLossShareAgreementsOtherRealEstateOwnedAndRepossessions_c1aa727e-b029-a084-df69-a767ac2b4bda" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherRealEstateAndForeclosedAssets_981e6fe7-fa32-4b68-a956-d14acea056c4" xlink:to="loc_rnst_CoveredUnderLossShareAgreementsOtherRealEstateOwnedAndRepossessions_c1aa727e-b029-a084-df69-a767ac2b4bda" xlink:type="arc" />
    <link:loc xlink:href="rnst-20170630.xsd#rnst_NotCoveredUnderLossShareAgreementsOtherRealEstateOwnedAndRepossessions" xlink:label="loc_rnst_NotCoveredUnderLossShareAgreementsOtherRealEstateOwnedAndRepossessions_3d6102b9-c038-32d0-75dc-a767ad1b94e6" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherRealEstateAndForeclosedAssets_981e6fe7-fa32-4b68-a956-d14acea056c4" xlink:to="loc_rnst_NotCoveredUnderLossShareAgreementsOtherRealEstateOwnedAndRepossessions_3d6102b9-c038-32d0-75dc-a767ad1b94e6" xlink:type="arc" />
  </link:calculationLink>
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/OtherRealEstateOwnedDetails1" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherRealEstateDisposals" xlink:label="loc_us-gaap_OtherRealEstateDisposals_05b13e97-86b3-0396-56b4-bcabdcea6a62" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherRealEstateCoveredDisposals" xlink:label="loc_us-gaap_OtherRealEstateCoveredDisposals_c2f29b37-944f-c098-2e0e-66f6802b1aa9" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherRealEstateDisposals_05b13e97-86b3-0396-56b4-bcabdcea6a62" xlink:to="loc_us-gaap_OtherRealEstateCoveredDisposals_c2f29b37-944f-c098-2e0e-66f6802b1aa9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherRealEstateNonCoveredDisposals" xlink:label="loc_us-gaap_OtherRealEstateNonCoveredDisposals_5bf8bf09-b7fc-f0b9-4cba-c6cdf4cf8479" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherRealEstateDisposals_05b13e97-86b3-0396-56b4-bcabdcea6a62" xlink:to="loc_us-gaap_OtherRealEstateNonCoveredDisposals_5bf8bf09-b7fc-f0b9-4cba-c6cdf4cf8479" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherRealEstate" xlink:label="loc_us-gaap_OtherRealEstate_be450e1d-7c5c-a17b-d70d-3377929556d0" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherRealEstateCovered" xlink:label="loc_us-gaap_OtherRealEstateCovered_42616602-8819-dda7-222d-defc5622b4ce" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherRealEstate_be450e1d-7c5c-a17b-d70d-3377929556d0" xlink:to="loc_us-gaap_OtherRealEstateCovered_42616602-8819-dda7-222d-defc5622b4ce" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherRealEstateNonCovered" xlink:label="loc_us-gaap_OtherRealEstateNonCovered_388da6d1-35a3-7325-22ab-7b089e692b6e" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherRealEstate_be450e1d-7c5c-a17b-d70d-3377929556d0" xlink:to="loc_us-gaap_OtherRealEstateNonCovered_388da6d1-35a3-7325-22ab-7b089e692b6e" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherRealEstateImprovements" xlink:label="loc_us-gaap_OtherRealEstateImprovements_a36546ab-d45d-779d-6b84-dbf34468b11d" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherRealEstateCoveredImprovements" xlink:label="loc_us-gaap_OtherRealEstateCoveredImprovements_44d0873a-74f6-61f5-f637-f114637c5603" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherRealEstateImprovements_a36546ab-d45d-779d-6b84-dbf34468b11d" xlink:to="loc_us-gaap_OtherRealEstateCoveredImprovements_44d0873a-74f6-61f5-f637-f114637c5603" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherRealEstateNonCoveredImprovements" xlink:label="loc_us-gaap_OtherRealEstateNonCoveredImprovements_e40b9b24-b3fb-3b1f-26d8-49c728fd9cc4" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherRealEstateImprovements_a36546ab-d45d-779d-6b84-dbf34468b11d" xlink:to="loc_us-gaap_OtherRealEstateNonCoveredImprovements_e40b9b24-b3fb-3b1f-26d8-49c728fd9cc4" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherRealEstateValuationAdjustments" xlink:label="loc_us-gaap_OtherRealEstateValuationAdjustments_4dd8efc8-3d34-17ad-01c2-71f5769588ac" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherRealEstateCoveredValuationAdjustments" xlink:label="loc_us-gaap_OtherRealEstateCoveredValuationAdjustments_40d3fd70-9727-bbec-5ae7-b3cd53744b6f" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherRealEstateValuationAdjustments_4dd8efc8-3d34-17ad-01c2-71f5769588ac" xlink:to="loc_us-gaap_OtherRealEstateCoveredValuationAdjustments_40d3fd70-9727-bbec-5ae7-b3cd53744b6f" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherRealEstateNonCoveredValuationAdjustments" xlink:label="loc_us-gaap_OtherRealEstateNonCoveredValuationAdjustments_aaa9a4d2-c5d6-dca7-003e-5f3b45e7da15" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherRealEstateValuationAdjustments_4dd8efc8-3d34-17ad-01c2-71f5769588ac" xlink:to="loc_us-gaap_OtherRealEstateNonCoveredValuationAdjustments_aaa9a4d2-c5d6-dca7-003e-5f3b45e7da15" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherRealEstatePeriodIncreaseDecrease" xlink:label="loc_us-gaap_OtherRealEstatePeriodIncreaseDecrease_2a3898c9-b7ec-1fbf-fcdb-bf1eed5053e1" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherRealEstateCoveredPeriodIncreaseDecrease" xlink:label="loc_us-gaap_OtherRealEstateCoveredPeriodIncreaseDecrease_90f4ce6c-af31-ad6d-5330-e9d9c6dcd3ea" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherRealEstatePeriodIncreaseDecrease_2a3898c9-b7ec-1fbf-fcdb-bf1eed5053e1" xlink:to="loc_us-gaap_OtherRealEstateCoveredPeriodIncreaseDecrease_90f4ce6c-af31-ad6d-5330-e9d9c6dcd3ea" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_OtherRealEstateNonCoveredPeriodIncreaseDecrease" xlink:label="loc_us-gaap_OtherRealEstateNonCoveredPeriodIncreaseDecrease_9f3c4f3d-41ab-f0a4-b06e-91708732420f" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_OtherRealEstatePeriodIncreaseDecrease_2a3898c9-b7ec-1fbf-fcdb-bf1eed5053e1" xlink:to="loc_us-gaap_OtherRealEstateNonCoveredPeriodIncreaseDecrease_9f3c4f3d-41ab-f0a4-b06e-91708732420f" xlink:type="arc" />
    <link:loc xlink:href="rnst-20170630.xsd#rnst_OtherRealEstateTransfersOfLoans" xlink:label="loc_rnst_OtherRealEstateTransfersOfLoans_8b918a46-1f32-301f-7d68-a767ae75c9f6" xlink:type="locator" />
    <link:loc xlink:href="rnst-20170630.xsd#rnst_OtherRealEstateCoveredTransfersOfLoans" xlink:label="loc_rnst_OtherRealEstateCoveredTransfersOfLoans_f9c01c5f-e76b-b5ea-c156-a767ae0b9dae" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_rnst_OtherRealEstateTransfersOfLoans_8b918a46-1f32-301f-7d68-a767ae75c9f6" xlink:to="loc_rnst_OtherRealEstateCoveredTransfersOfLoans_f9c01c5f-e76b-b5ea-c156-a767ae0b9dae" xlink:type="arc" />
    <link:loc xlink:href="rnst-20170630.xsd#rnst_OtherRealEstateNotCoveredTransfersOfLoans" xlink:label="loc_rnst_OtherRealEstateNotCoveredTransfersOfLoans_d04635fe-c392-8a03-55b8-a767acd606bf" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_rnst_OtherRealEstateTransfersOfLoans_8b918a46-1f32-301f-7d68-a767ae75c9f6" xlink:to="loc_rnst_OtherRealEstateNotCoveredTransfersOfLoans_d04635fe-c392-8a03-55b8-a767acd606bf" xlink:type="arc" />
  </link:calculationLink>
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/OtherRealEstateOwnedDetails2" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ForeclosedRealEstateExpense" xlink:label="loc_us-gaap_ForeclosedRealEstateExpense_79506dd2-3fe6-218c-a401-af0073b416b0" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CostOfPropertyRepairsAndMaintenance" xlink:label="loc_us-gaap_CostOfPropertyRepairsAndMaintenance_e61f3889-eb64-4f84-6c71-abe249f1b989" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_ForeclosedRealEstateExpense_79506dd2-3fe6-218c-a401-af0073b416b0" xlink:to="loc_us-gaap_CostOfPropertyRepairsAndMaintenance_e61f3889-eb64-4f84-6c71-abe249f1b989" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_RealEstateTaxesAndInsurance" xlink:label="loc_us-gaap_RealEstateTaxesAndInsurance_c9434c2e-5b0a-6715-d48c-2d13174d6577" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_ForeclosedRealEstateExpense_79506dd2-3fe6-218c-a401-af0073b416b0" xlink:to="loc_us-gaap_RealEstateTaxesAndInsurance_c9434c2e-5b0a-6715-d48c-2d13174d6577" xlink:type="arc" />
    <link:loc xlink:href="rnst-20170630.xsd#rnst_OtherRealEstateOwnedImpairments" xlink:label="loc_rnst_OtherRealEstateOwnedImpairments_ab59fc35-56d2-2e22-06a7-a767ac15796f" xlink:type="locator" />
    <link:calculationArc order="3" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_ForeclosedRealEstateExpense_79506dd2-3fe6-218c-a401-af0073b416b0" xlink:to="loc_rnst_OtherRealEstateOwnedImpairments_ab59fc35-56d2-2e22-06a7-a767ac15796f" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_GainsLossesOnSalesOfOtherRealEstate" xlink:label="loc_us-gaap_GainsLossesOnSalesOfOtherRealEstate_64e6ffc2-2e49-1f95-1346-70fd1dbe1fe6" xlink:type="locator" />
    <link:calculationArc order="4" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_ForeclosedRealEstateExpense_79506dd2-3fe6-218c-a401-af0073b416b0" xlink:to="loc_us-gaap_GainsLossesOnSalesOfOtherRealEstate_64e6ffc2-2e49-1f95-1346-70fd1dbe1fe6" xlink:type="arc" />
    <link:loc xlink:href="rnst-20170630.xsd#rnst_OtherRealEstateOwnedRentalIncome" xlink:label="loc_rnst_OtherRealEstateOwnedRentalIncome_25f69a2c-216c-828c-1095-a767aba66b98" xlink:type="locator" />
    <link:calculationArc order="5" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_ForeclosedRealEstateExpense_79506dd2-3fe6-218c-a401-af0073b416b0" xlink:to="loc_rnst_OtherRealEstateOwnedRentalIncome_25f69a2c-216c-828c-1095-a767aba66b98" xlink:type="arc" />
  </link:calculationLink>
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/OtherRealEstateOwnedDetailsTextual" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/OtherRealEstateOwnedTables" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/PurchasedLoans" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/PurchasedLoansDetails" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/PurchasedLoansDetails1" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/PurchasedLoansDetails10" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/PurchasedLoansDetails2" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/PurchasedLoansDetails3" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/PurchasedLoansDetails4" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/PurchasedLoansDetails5" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/PurchasedLoansDetails6" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/PurchasedLoansDetails7" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/PurchasedLoansDetails8" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CertainLoansAcquiredInTransferAccountedForAsDebtSecuritiesAcquiredDuringPeriodCashFlowsExpectedToBeCollectedAtAcquisition" xlink:label="loc_us-gaap_CertainLoansAcquiredInTransferAccountedForAsDebtSecuritiesAcquiredDuringPeriodCashFlowsExpectedToBeCollectedAtAcquisition_600707e5-542e-a7fd-fe44-2b91f5be7455" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CertainLoansAcquiredInTransferAccountedForAsDebtSecuritiesAcquiredDuringPeriodContractuallyRequiredPaymentsReceivableAtAcquisition" xlink:label="loc_us-gaap_CertainLoansAcquiredInTransferAccountedForAsDebtSecuritiesAcquiredDuringPeriodContractuallyRequiredPaymentsReceivableAtAcquisition_96728041-f0ea-d32a-629b-d8f985c2cbe0" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CertainLoansAcquiredInTransferAccountedForAsDebtSecuritiesAcquiredDuringPeriodCashFlowsExpectedToBeCollectedAtAcquisition_600707e5-542e-a7fd-fe44-2b91f5be7455" xlink:to="loc_us-gaap_CertainLoansAcquiredInTransferAccountedForAsDebtSecuritiesAcquiredDuringPeriodContractuallyRequiredPaymentsReceivableAtAcquisition_96728041-f0ea-d32a-629b-d8f985c2cbe0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_CertainLoansAcquiredInTransferNonaccretableDifference" xlink:label="loc_us-gaap_CertainLoansAcquiredInTransferNonaccretableDifference_cfd2613b-2eba-c921-bf74-82385dc48c29" xlink:type="locator" />
    <link:calculationArc order="2" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_CertainLoansAcquiredInTransferAccountedForAsDebtSecuritiesAcquiredDuringPeriodCashFlowsExpectedToBeCollectedAtAcquisition_600707e5-542e-a7fd-fe44-2b91f5be7455" xlink:to="loc_us-gaap_CertainLoansAcquiredInTransferNonaccretableDifference_cfd2613b-2eba-c921-bf74-82385dc48c29" xlink:type="arc" />
  </link:calculationLink>
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/PurchasedLoansDetails9" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/PurchasedLoansDetailsTextual" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/PurchasedLoansTables" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/RedemptionOfLongTermDebt" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/RedemptionOfLongTermDebtDetails" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/RegulatoryMatters" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/RegulatoryMattersDetails" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/RegulatoryMattersDetails1" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/RegulatoryMattersTables" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/Securities" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/SecuritiesDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_HeldToMaturitySecuritiesAmortizedCostBeforeOtherThanTemporaryImpairment" xlink:label="loc_us-gaap_HeldToMaturitySecuritiesAmortizedCostBeforeOtherThanTemporaryImpairment_46f75f3f-4ced-36de-04ea-a031e3d4605c" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_HeldToMaturitySecuritiesAccumulatedUnrecognizedHoldingGain" xlink:label="loc_us-gaap_HeldToMaturitySecuritiesAccumulatedUnrecognizedHoldingGain_034611ea-64e8-e6ac-6b57-530c530d2463" xlink:type="locator" />
    <link:calculationArc order="1" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_HeldToMaturitySecuritiesAmortizedCostBeforeOtherThanTemporaryImpairment_46f75f3f-4ced-36de-04ea-a031e3d4605c" xlink:to="loc_us-gaap_HeldToMaturitySecuritiesAccumulatedUnrecognizedHoldingGain_034611ea-64e8-e6ac-6b57-530c530d2463" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_HeldToMaturitySecuritiesAccumulatedUnrecognizedHoldingLoss" xlink:label="loc_us-gaap_HeldToMaturitySecuritiesAccumulatedUnrecognizedHoldingLoss_04cbaa59-5eb0-e143-0a21-a553da1ab158" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_HeldToMaturitySecuritiesAmortizedCostBeforeOtherThanTemporaryImpairment_46f75f3f-4ced-36de-04ea-a031e3d4605c" xlink:to="loc_us-gaap_HeldToMaturitySecuritiesAccumulatedUnrecognizedHoldingLoss_04cbaa59-5eb0-e143-0a21-a553da1ab158" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_HeldToMaturitySecuritiesFairValue" xlink:label="loc_us-gaap_HeldToMaturitySecuritiesFairValue_317678d5-aa75-7221-6f7e-512a1e9594ce" xlink:type="locator" />
    <link:calculationArc order="3" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_HeldToMaturitySecuritiesAmortizedCostBeforeOtherThanTemporaryImpairment_46f75f3f-4ced-36de-04ea-a031e3d4605c" xlink:to="loc_us-gaap_HeldToMaturitySecuritiesFairValue_317678d5-aa75-7221-6f7e-512a1e9594ce" xlink:type="arc" />
  </link:calculationLink>
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/SecuritiesDetails1" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/SecuritiesDetails2" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AvailableForSaleSecuritiesGrossRealizedGainLossNet" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesGrossRealizedGainLossNet_55f58d9b-a4cc-27e0-d4b9-b08916d106f9" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AvailableForSaleSecuritiesGrossRealizedGains" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesGrossRealizedGains_0c3203dd-4b24-5624-3641-9ab08b1db8c0" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesGrossRealizedGainLossNet_55f58d9b-a4cc-27e0-d4b9-b08916d106f9" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesGrossRealizedGains_0c3203dd-4b24-5624-3641-9ab08b1db8c0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AvailableForSaleSecuritiesGrossRealizedLosses" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesGrossRealizedLosses_0172551e-b356-9857-889b-d8d2ba876247" xlink:type="locator" />
    <link:calculationArc order="2" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesGrossRealizedGainLossNet_55f58d9b-a4cc-27e0-d4b9-b08916d106f9" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesGrossRealizedLosses_0172551e-b356-9857-889b-d8d2ba876247" xlink:type="arc" />
  </link:calculationLink>
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/SecuritiesDetails3" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AvailableForSaleSecuritiesAmortizedCost" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesAmortizedCost_30dc6014-97a8-c9af-5d13-c233c1983f7f" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearAmortizedCost" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearAmortizedCost_065ac417-143a-3361-82a5-1e59ffd9749a" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesAmortizedCost_30dc6014-97a8-c9af-5d13-c233c1983f7f" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearAmortizedCost_065ac417-143a-3361-82a5-1e59ffd9749a" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtMaturitiesAfterOneThroughFiveYearsAmortizedCost" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesAfterOneThroughFiveYearsAmortizedCost_6806c6da-7794-6cc2-dea6-0fe1f4c6a026" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesAmortizedCost_30dc6014-97a8-c9af-5d13-c233c1983f7f" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesAfterOneThroughFiveYearsAmortizedCost_6806c6da-7794-6cc2-dea6-0fe1f4c6a026" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtMaturitiesAfterFiveThroughTenYearsAmortizedCost" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesAfterFiveThroughTenYearsAmortizedCost_c1571bda-5b61-dcae-c5bf-c051d205fcb0" xlink:type="locator" />
    <link:calculationArc order="3" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesAmortizedCost_30dc6014-97a8-c9af-5d13-c233c1983f7f" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesAfterFiveThroughTenYearsAmortizedCost_c1571bda-5b61-dcae-c5bf-c051d205fcb0" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtMaturitiesAfterTenYearsAmortizedCost" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesAfterTenYearsAmortizedCost_ff34ba87-e8d3-6e7f-88aa-c1d3f9f922ea" xlink:type="locator" />
    <link:calculationArc order="4" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesAmortizedCost_30dc6014-97a8-c9af-5d13-c233c1983f7f" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesAfterTenYearsAmortizedCost_ff34ba87-e8d3-6e7f-88aa-c1d3f9f922ea" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithoutSingleMaturityDateAmortizedCost" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithoutSingleMaturityDateAmortizedCost_ac973b63-1234-e9dc-6850-581bee09202d" xlink:type="locator" />
    <link:calculationArc order="5" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesAmortizedCost_30dc6014-97a8-c9af-5d13-c233c1983f7f" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithoutSingleMaturityDateAmortizedCost_ac973b63-1234-e9dc-6850-581bee09202d" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis" xlink:label="loc_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis_fc961581-2899-aa00-cc82-b67bd4267bb3" xlink:type="locator" />
    <link:calculationArc order="6" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesAmortizedCost_30dc6014-97a8-c9af-5d13-c233c1983f7f" xlink:to="loc_us-gaap_AvailableForSaleDebtSecuritiesAmortizedCostBasis_fc961581-2899-aa00-cc82-b67bd4267bb3" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_HeldToMaturitySecuritiesFairValue" xlink:label="loc_us-gaap_HeldToMaturitySecuritiesFairValue_317678d5-aa75-7221-6f7e-512a1e9594ce" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_HeldToMaturitySecuritiesDebtMaturitiesWithinOneYearFairValue" xlink:label="loc_us-gaap_HeldToMaturitySecuritiesDebtMaturitiesWithinOneYearFairValue_837d1260-daa2-488c-64c8-2e7be5aee8de" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_HeldToMaturitySecuritiesFairValue_317678d5-aa75-7221-6f7e-512a1e9594ce" xlink:to="loc_us-gaap_HeldToMaturitySecuritiesDebtMaturitiesWithinOneYearFairValue_837d1260-daa2-488c-64c8-2e7be5aee8de" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_HeldToMaturitySecuritiesDebtMaturitiesAfterOneThroughFiveYearsFairValue" xlink:label="loc_us-gaap_HeldToMaturitySecuritiesDebtMaturitiesAfterOneThroughFiveYearsFairValue_2c901eb8-b331-77d7-037a-709db533c963" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_HeldToMaturitySecuritiesFairValue_317678d5-aa75-7221-6f7e-512a1e9594ce" xlink:to="loc_us-gaap_HeldToMaturitySecuritiesDebtMaturitiesAfterOneThroughFiveYearsFairValue_2c901eb8-b331-77d7-037a-709db533c963" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_HeldToMaturitySecuritiesDebtMaturitiesAfterFiveThroughTenYearsFairValue" xlink:label="loc_us-gaap_HeldToMaturitySecuritiesDebtMaturitiesAfterFiveThroughTenYearsFairValue_45b1bcf4-633a-aca2-3c30-423160f2a118" xlink:type="locator" />
    <link:calculationArc order="3" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_HeldToMaturitySecuritiesFairValue_317678d5-aa75-7221-6f7e-512a1e9594ce" xlink:to="loc_us-gaap_HeldToMaturitySecuritiesDebtMaturitiesAfterFiveThroughTenYearsFairValue_45b1bcf4-633a-aca2-3c30-423160f2a118" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_HeldToMaturitySecuritiesDebtMaturitiesAfterTenYearsFairValue" xlink:label="loc_us-gaap_HeldToMaturitySecuritiesDebtMaturitiesAfterTenYearsFairValue_54df4125-09a5-7d47-a86b-6d3b4b7ba2f9" xlink:type="locator" />
    <link:calculationArc order="4" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_HeldToMaturitySecuritiesFairValue_317678d5-aa75-7221-6f7e-512a1e9594ce" xlink:to="loc_us-gaap_HeldToMaturitySecuritiesDebtMaturitiesAfterTenYearsFairValue_54df4125-09a5-7d47-a86b-6d3b4b7ba2f9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AvailableForSaleSecurities" xlink:label="loc_us-gaap_AvailableForSaleSecurities_d444402b-921b-e0fa-119c-908ab66850af" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearFairValue" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearFairValue_4836856d-11b6-313b-8616-6a2c8b77e26f" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleSecurities_d444402b-921b-e0fa-119c-908ab66850af" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithinOneYearFairValue_4836856d-11b6-313b-8616-6a2c8b77e26f" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtMaturitiesAfterOneThroughFiveYearsFairValue" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesAfterOneThroughFiveYearsFairValue_c92402e9-bd0b-d11c-b52e-45b5c23d49be" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleSecurities_d444402b-921b-e0fa-119c-908ab66850af" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesAfterOneThroughFiveYearsFairValue_c92402e9-bd0b-d11c-b52e-45b5c23d49be" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtMaturitiesAfterFiveThroughTenYearsFairValue" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesAfterFiveThroughTenYearsFairValue_4e9a5751-649f-39a9-c9ec-844be0df352b" xlink:type="locator" />
    <link:calculationArc order="3" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleSecurities_d444402b-921b-e0fa-119c-908ab66850af" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesAfterFiveThroughTenYearsFairValue_4e9a5751-649f-39a9-c9ec-844be0df352b" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtMaturitiesAfterTenYearsFairValue" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesAfterTenYearsFairValue_e94acabe-050f-59b3-6024-05630a9bf579" xlink:type="locator" />
    <link:calculationArc order="4" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleSecurities_d444402b-921b-e0fa-119c-908ab66850af" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesAfterTenYearsFairValue_e94acabe-050f-59b3-6024-05630a9bf579" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithoutSingleMaturityDateFairValue" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithoutSingleMaturityDateFairValue_11c917bd-9af8-6ef7-e11a-4b124839ec0d" xlink:type="locator" />
    <link:calculationArc order="5" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleSecurities_d444402b-921b-e0fa-119c-908ab66850af" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesDebtMaturitiesWithoutSingleMaturityDateFairValue_11c917bd-9af8-6ef7-e11a-4b124839ec0d" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_HeldToMaturitySecuritiesAmortizedCostBeforeOtherThanTemporaryImpairment" xlink:label="loc_us-gaap_HeldToMaturitySecuritiesAmortizedCostBeforeOtherThanTemporaryImpairment_46f75f3f-4ced-36de-04ea-a031e3d4605c" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_HeldToMaturitySecuritiesDebtMaturitiesWithinOneYearNetCarryingAmount" xlink:label="loc_us-gaap_HeldToMaturitySecuritiesDebtMaturitiesWithinOneYearNetCarryingAmount_01f5fca0-0070-5249-0eb7-1cb84a39b7e6" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_HeldToMaturitySecuritiesAmortizedCostBeforeOtherThanTemporaryImpairment_46f75f3f-4ced-36de-04ea-a031e3d4605c" xlink:to="loc_us-gaap_HeldToMaturitySecuritiesDebtMaturitiesWithinOneYearNetCarryingAmount_01f5fca0-0070-5249-0eb7-1cb84a39b7e6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_HeldToMaturitySecuritiesDebtMaturitiesAfterOneThroughFiveYearsNetCarryingAmount" xlink:label="loc_us-gaap_HeldToMaturitySecuritiesDebtMaturitiesAfterOneThroughFiveYearsNetCarryingAmount_12128751-e7de-aad7-24b3-5ab9e63f309b" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_HeldToMaturitySecuritiesAmortizedCostBeforeOtherThanTemporaryImpairment_46f75f3f-4ced-36de-04ea-a031e3d4605c" xlink:to="loc_us-gaap_HeldToMaturitySecuritiesDebtMaturitiesAfterOneThroughFiveYearsNetCarryingAmount_12128751-e7de-aad7-24b3-5ab9e63f309b" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_HeldToMaturitySecuritiesDebtMaturitiesAfterFiveThroughTenYearsNetCarryingAmount" xlink:label="loc_us-gaap_HeldToMaturitySecuritiesDebtMaturitiesAfterFiveThroughTenYearsNetCarryingAmount_9b0a2925-c38c-2c54-df67-7b5d234b8836" xlink:type="locator" />
    <link:calculationArc order="3" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_HeldToMaturitySecuritiesAmortizedCostBeforeOtherThanTemporaryImpairment_46f75f3f-4ced-36de-04ea-a031e3d4605c" xlink:to="loc_us-gaap_HeldToMaturitySecuritiesDebtMaturitiesAfterFiveThroughTenYearsNetCarryingAmount_9b0a2925-c38c-2c54-df67-7b5d234b8836" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_HeldToMaturitySecuritiesDebtMaturitiesAfterTenYearsNetCarryingAmount" xlink:label="loc_us-gaap_HeldToMaturitySecuritiesDebtMaturitiesAfterTenYearsNetCarryingAmount_991033c0-c528-5d4a-c165-d7ea56370526" xlink:type="locator" />
    <link:calculationArc order="4" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_HeldToMaturitySecuritiesAmortizedCostBeforeOtherThanTemporaryImpairment_46f75f3f-4ced-36de-04ea-a031e3d4605c" xlink:to="loc_us-gaap_HeldToMaturitySecuritiesDebtMaturitiesAfterTenYearsNetCarryingAmount_991033c0-c528-5d4a-c165-d7ea56370526" xlink:type="arc" />
  </link:calculationLink>
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/SecuritiesDetails4" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_HeldToMaturitySecuritiesContinuousUnrealizedLossPositionFairValue" xlink:label="loc_us-gaap_HeldToMaturitySecuritiesContinuousUnrealizedLossPositionFairValue_ae410534-ff1f-afef-7c75-bbe62f56894d" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_HeldToMaturitySecuritiesContinuousUnrealizedLossPositionLessThanTwelveMonthsFairValue" xlink:label="loc_us-gaap_HeldToMaturitySecuritiesContinuousUnrealizedLossPositionLessThanTwelveMonthsFairValue_4b9ba026-7273-0821-7d62-bb1019365c55" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_HeldToMaturitySecuritiesContinuousUnrealizedLossPositionFairValue_ae410534-ff1f-afef-7c75-bbe62f56894d" xlink:to="loc_us-gaap_HeldToMaturitySecuritiesContinuousUnrealizedLossPositionLessThanTwelveMonthsFairValue_4b9ba026-7273-0821-7d62-bb1019365c55" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_HeldToMaturitySecuritiesContinuousUnrealizedLossPositionTwelveMonthsOrLongerFairValue" xlink:label="loc_us-gaap_HeldToMaturitySecuritiesContinuousUnrealizedLossPositionTwelveMonthsOrLongerFairValue_da993c7c-63f5-a242-9f8a-6e9d9ff288c6" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_HeldToMaturitySecuritiesContinuousUnrealizedLossPositionFairValue_ae410534-ff1f-afef-7c75-bbe62f56894d" xlink:to="loc_us-gaap_HeldToMaturitySecuritiesContinuousUnrealizedLossPositionTwelveMonthsOrLongerFairValue_da993c7c-63f5-a242-9f8a-6e9d9ff288c6" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AvailableforsaleSecuritiesInUnrealizedLossPositionsQualitativeDisclosureNumberOfPositions1" xlink:label="loc_us-gaap_AvailableforsaleSecuritiesInUnrealizedLossPositionsQualitativeDisclosureNumberOfPositions1_111b7cba-e95e-3799-f7b7-f27c52cbd965" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AvailableForSaleSecuritiesInUnrealizedLossPositionsQualitativeDisclosureNumberOfPositionsLessThanOneYear" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesInUnrealizedLossPositionsQualitativeDisclosureNumberOfPositionsLessThanOneYear_6bbb0e70-697e-73fd-d0fa-86f9d4dfc3fb" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableforsaleSecuritiesInUnrealizedLossPositionsQualitativeDisclosureNumberOfPositions1_111b7cba-e95e-3799-f7b7-f27c52cbd965" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesInUnrealizedLossPositionsQualitativeDisclosureNumberOfPositionsLessThanOneYear_6bbb0e70-697e-73fd-d0fa-86f9d4dfc3fb" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AvailableforsaleSecuritiesInUnrealizedLossPositionsQualitativeDisclosureNumberOfPositionsGreaterThanOrEqualToOneYear" xlink:label="loc_us-gaap_AvailableforsaleSecuritiesInUnrealizedLossPositionsQualitativeDisclosureNumberOfPositionsGreaterThanOrEqualToOneYear_7e4980cb-d5e7-da42-9b43-5fe24011710f" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableforsaleSecuritiesInUnrealizedLossPositionsQualitativeDisclosureNumberOfPositions1_111b7cba-e95e-3799-f7b7-f27c52cbd965" xlink:to="loc_us-gaap_AvailableforsaleSecuritiesInUnrealizedLossPositionsQualitativeDisclosureNumberOfPositionsGreaterThanOrEqualToOneYear_7e4980cb-d5e7-da42-9b43-5fe24011710f" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_HeldtomaturitySecuritiesContinuousUnrealizedLossPositionAggregateLoss" xlink:label="loc_us-gaap_HeldtomaturitySecuritiesContinuousUnrealizedLossPositionAggregateLoss_fb5f73af-dfb6-c569-2f8f-3fa9d986b946" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_HeldtomaturitySecuritiesContinuousUnrealizedLossPositionLessThan12MonthsAggregateLoss" xlink:label="loc_us-gaap_HeldtomaturitySecuritiesContinuousUnrealizedLossPositionLessThan12MonthsAggregateLoss_c0352751-0b55-4467-a418-f31f2523b97a" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_HeldtomaturitySecuritiesContinuousUnrealizedLossPositionAggregateLoss_fb5f73af-dfb6-c569-2f8f-3fa9d986b946" xlink:to="loc_us-gaap_HeldtomaturitySecuritiesContinuousUnrealizedLossPositionLessThan12MonthsAggregateLoss_c0352751-0b55-4467-a418-f31f2523b97a" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_HeldtomaturitySecuritiesContinuousUnrealizedLossPosition12MonthsOrLongerAggregateLoss" xlink:label="loc_us-gaap_HeldtomaturitySecuritiesContinuousUnrealizedLossPosition12MonthsOrLongerAggregateLoss_bf81301f-9ec2-56ba-921d-be1562cf3e80" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_HeldtomaturitySecuritiesContinuousUnrealizedLossPositionAggregateLoss_fb5f73af-dfb6-c569-2f8f-3fa9d986b946" xlink:to="loc_us-gaap_HeldtomaturitySecuritiesContinuousUnrealizedLossPosition12MonthsOrLongerAggregateLoss_bf81301f-9ec2-56ba-921d-be1562cf3e80" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AvailableForSaleSecuritiesContinuousUnrealizedLossPositionAccumulatedLoss" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesContinuousUnrealizedLossPositionAccumulatedLoss_2e09f20d-7547-1a18-6f83-8a0ce6a75ae4" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AvailableForSaleSecuritiesContinuousUnrealizedLossPositionLessThan12MonthsAccumulatedLoss" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesContinuousUnrealizedLossPositionLessThan12MonthsAccumulatedLoss_aaf3e830-a5d9-ffa3-4995-c9e738f331db" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesContinuousUnrealizedLossPositionAccumulatedLoss_2e09f20d-7547-1a18-6f83-8a0ce6a75ae4" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesContinuousUnrealizedLossPositionLessThan12MonthsAccumulatedLoss_aaf3e830-a5d9-ffa3-4995-c9e738f331db" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AvailableForSaleSecuritiesContinuousUnrealizedLossPosition12MonthsOrLongerAccumulatedLoss" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesContinuousUnrealizedLossPosition12MonthsOrLongerAccumulatedLoss_80d8afbb-83ba-fc94-42ba-ea8166197445" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesContinuousUnrealizedLossPositionAccumulatedLoss_2e09f20d-7547-1a18-6f83-8a0ce6a75ae4" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesContinuousUnrealizedLossPosition12MonthsOrLongerAccumulatedLoss_80d8afbb-83ba-fc94-42ba-ea8166197445" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AvailableForSaleSecuritiesContinuousUnrealizedLossPositionFairValue" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesContinuousUnrealizedLossPositionFairValue_00e7a94b-1ec9-6499-7f0a-2050ff159115" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AvailableForSaleSecuritiesContinuousUnrealizedLossPositionLessThanTwelveMonthsFairValue" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesContinuousUnrealizedLossPositionLessThanTwelveMonthsFairValue_a1dd3f1b-4c24-2372-1a98-24b25891a665" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesContinuousUnrealizedLossPositionFairValue_00e7a94b-1ec9-6499-7f0a-2050ff159115" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesContinuousUnrealizedLossPositionLessThanTwelveMonthsFairValue_a1dd3f1b-4c24-2372-1a98-24b25891a665" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AvailableForSaleSecuritiesContinuousUnrealizedLossPositionTwelveMonthsOrLongerFairValue" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesContinuousUnrealizedLossPositionTwelveMonthsOrLongerFairValue_7b1de9af-f23a-d7bf-8a2c-7efccf28ddba" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesContinuousUnrealizedLossPositionFairValue_00e7a94b-1ec9-6499-7f0a-2050ff159115" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesContinuousUnrealizedLossPositionTwelveMonthsOrLongerFairValue_7b1de9af-f23a-d7bf-8a2c-7efccf28ddba" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_HeldToMaturitySecuritiesInUnrealizedLossPositionsQualitativeDisclosureNumberOfPositions" xlink:label="loc_us-gaap_HeldToMaturitySecuritiesInUnrealizedLossPositionsQualitativeDisclosureNumberOfPositions_e4590af1-fbfb-8240-e71e-c705c11e0076" xlink:type="locator" />
    <link:loc xlink:href="rnst-20170630.xsd#rnst_HeldtomaturitiySecuritiesinUnrealizedLossPositionsQualitativeDisclosureNumberofPositionsLessthanOneYear" xlink:label="loc_rnst_HeldtomaturitiySecuritiesinUnrealizedLossPositionsQualitativeDisclosureNumberofPositionsLessthanOneYear_a0b17f9e-405f-b8f2-1a68-a767ad363da1" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_HeldToMaturitySecuritiesInUnrealizedLossPositionsQualitativeDisclosureNumberOfPositions_e4590af1-fbfb-8240-e71e-c705c11e0076" xlink:to="loc_rnst_HeldtomaturitiySecuritiesinUnrealizedLossPositionsQualitativeDisclosureNumberofPositionsLessthanOneYear_a0b17f9e-405f-b8f2-1a68-a767ad363da1" xlink:type="arc" />
    <link:loc xlink:href="rnst-20170630.xsd#rnst_HeldtomaturitySecuritiesinUnrealizedLossPositionsQualitativeDisclosureNumberofPositionsGreaterthanorEqualtoOneYear" xlink:label="loc_rnst_HeldtomaturitySecuritiesinUnrealizedLossPositionsQualitativeDisclosureNumberofPositionsGreaterthanorEqualtoOneYear_4e97f177-815e-0a11-6d6a-a767ab4e2082" xlink:type="locator" />
    <link:calculationArc order="2" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_HeldToMaturitySecuritiesInUnrealizedLossPositionsQualitativeDisclosureNumberOfPositions_e4590af1-fbfb-8240-e71e-c705c11e0076" xlink:to="loc_rnst_HeldtomaturitySecuritiesinUnrealizedLossPositionsQualitativeDisclosureNumberofPositionsGreaterthanorEqualtoOneYear_4e97f177-815e-0a11-6d6a-a767ab4e2082" xlink:type="arc" />
  </link:calculationLink>
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/SecuritiesDetails5" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AvailableForSaleSecuritiesAmortizedCost" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesAmortizedCost_30dc6014-97a8-c9af-5d13-c233c1983f7f" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AvailableForSaleSecurities" xlink:label="loc_us-gaap_AvailableForSaleSecurities_d444402b-921b-e0fa-119c-908ab66850af" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesAmortizedCost_30dc6014-97a8-c9af-5d13-c233c1983f7f" xlink:to="loc_us-gaap_AvailableForSaleSecurities_d444402b-921b-e0fa-119c-908ab66850af" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_AvailableForSaleSecuritiesAccumulatedGrossUnrealizedGainLossBeforeTax" xlink:label="loc_us-gaap_AvailableForSaleSecuritiesAccumulatedGrossUnrealizedGainLossBeforeTax_df53ae63-0d8f-8b21-1f34-74b48abee9e6" xlink:type="locator" />
    <link:calculationArc order="2" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_AvailableForSaleSecuritiesAmortizedCost_30dc6014-97a8-c9af-5d13-c233c1983f7f" xlink:to="loc_us-gaap_AvailableForSaleSecuritiesAccumulatedGrossUnrealizedGainLossBeforeTax_df53ae63-0d8f-8b21-1f34-74b48abee9e6" xlink:type="arc" />
  </link:calculationLink>
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/SecuritiesDetails6" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/SecuritiesDetailsTextual" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/SecuritiesTables" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/SegmentReporting" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/SegmentReportingDetails" xlink:type="extended">
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_0eb47183-f513-314d-ceda-ee2412d9eee8" xlink:type="locator" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_InterestIncomeExpenseNet" xlink:label="loc_us-gaap_InterestIncomeExpenseNet_1df5100d-c7c3-27c8-1405-81abbd3827e1" xlink:type="locator" />
    <link:calculationArc order="1" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_0eb47183-f513-314d-ceda-ee2412d9eee8" xlink:to="loc_us-gaap_InterestIncomeExpenseNet_1df5100d-c7c3-27c8-1405-81abbd3827e1" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_ProvisionForLoanAndLeaseLosses" xlink:label="loc_us-gaap_ProvisionForLoanAndLeaseLosses_e0ca8321-ebf3-2764-9c0e-6cfd763aef57" xlink:type="locator" />
    <link:calculationArc order="2" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_0eb47183-f513-314d-ceda-ee2412d9eee8" xlink:to="loc_us-gaap_ProvisionForLoanAndLeaseLosses_e0ca8321-ebf3-2764-9c0e-6cfd763aef57" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_NoninterestIncome" xlink:label="loc_us-gaap_NoninterestIncome_85d8e349-2d49-3422-00b4-05065a60f6f9" xlink:type="locator" />
    <link:calculationArc order="3" weight="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_0eb47183-f513-314d-ceda-ee2412d9eee8" xlink:to="loc_us-gaap_NoninterestIncome_85d8e349-2d49-3422-00b4-05065a60f6f9" xlink:type="arc" />
    <link:loc xlink:href="http://xbrl.fasb.org/us-gaap/2017/elts/us-gaap-2017-01-31.xsd#us-gaap_NoninterestExpense" xlink:label="loc_us-gaap_NoninterestExpense_b9eb1ceb-6771-3351-1281-e8b3cd4f24bc" xlink:type="locator" />
    <link:calculationArc order="4" weight="-1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/summation-item" xlink:from="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesMinorityInterestAndIncomeLossFromEquityMethodInvestments_0eb47183-f513-314d-ceda-ee2412d9eee8" xlink:to="loc_us-gaap_NoninterestExpense_b9eb1ceb-6771-3351-1281-e8b3cd4f24bc" xlink:type="arc" />
  </link:calculationLink>
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/SegmentReportingTables" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/SummaryOfSignificantAccountingPolicies" xlink:type="extended" />
  <link:calculationLink xlink:role="http://www.renasantbank.com/role/SummaryOfSignificantAccountingPoliciesPolicies" xlink:type="extended" />
</link:linkbase>
