<?xml version="1.0" encoding="UTF-8"?>

<!--XBRL Document Created with the Workiva Platform-->
<!--Copyright 2024 Workiva-->
<!--r:385a6a2f-bb15-4836-8ff4-a13b7f0ed1b8,g:bb4be2e0-f23d-4314-b41b-46a07bb4f393-->
<link:linkbase xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:xbrldt="http://xbrl.org/2005/xbrldt" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
  <link:arcroleRef arcroleURI="http://xbrl.org/int/dim/arcrole/all" xlink:type="simple" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#all"/>
  <link:arcroleRef arcroleURI="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:type="simple" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#hypercube-dimension"/>
  <link:arcroleRef arcroleURI="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:type="simple" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#dimension-default"/>
  <link:arcroleRef arcroleURI="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:type="simple" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#dimension-domain"/>
  <link:arcroleRef arcroleURI="http://xbrl.org/int/dim/arcrole/domain-member" xlink:type="simple" xlink:href="http://www.xbrl.org/2005/xbrldt-2005.xsd#domain-member"/>
  <link:roleRef roleURI="http://www.fult.com/role/CoverPage" xlink:type="simple" xlink:href="fult-20240416.xsd#CoverPage"/>
  <link:definitionLink xlink:role="http://www.fult.com/role/CoverPage" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentInformationLineItems_4bba68f4-c312-42f7-a6f2-6b1561c54299" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_DocumentInformationLineItems"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentInformationTable_89fdf47c-8fd5-4b6e-a116-3423fd9faff9" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_DocumentInformationTable"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/all" xlink:from="loc_dei_DocumentInformationLineItems_4bba68f4-c312-42f7-a6f2-6b1561c54299" xlink:to="loc_dei_DocumentInformationTable_89fdf47c-8fd5-4b6e-a116-3423fd9faff9" xlink:type="arc" order="1" xbrldt:closed="true" xbrldt:contextElement="segment"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementClassOfStockAxis_b61ee087-b597-4e3c-8e2a-b3f7ebea42e5" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_StatementClassOfStockAxis"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/hypercube-dimension" xlink:from="loc_dei_DocumentInformationTable_89fdf47c-8fd5-4b6e-a116-3423fd9faff9" xlink:to="loc_us-gaap_StatementClassOfStockAxis_b61ee087-b597-4e3c-8e2a-b3f7ebea42e5" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfStockDomain_b61ee087-b597-4e3c-8e2a-b3f7ebea42e5_default" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ClassOfStockDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-default" xlink:from="loc_us-gaap_StatementClassOfStockAxis_b61ee087-b597-4e3c-8e2a-b3f7ebea42e5" xlink:to="loc_us-gaap_ClassOfStockDomain_b61ee087-b597-4e3c-8e2a-b3f7ebea42e5_default" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfStockDomain_eec33fe3-138c-4219-aae6-c8451a04143e" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_ClassOfStockDomain"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/dimension-domain" xlink:from="loc_us-gaap_StatementClassOfStockAxis_b61ee087-b597-4e3c-8e2a-b3f7ebea42e5" xlink:to="loc_us-gaap_ClassOfStockDomain_eec33fe3-138c-4219-aae6-c8451a04143e" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockMember_9d38e7a0-fbae-4ed1-830c-8b41f27e8aa3" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_CommonStockMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ClassOfStockDomain_eec33fe3-138c-4219-aae6-c8451a04143e" xlink:to="loc_us-gaap_CommonStockMember_9d38e7a0-fbae-4ed1-830c-8b41f27e8aa3" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SeriesAPreferredStockMember_d6145b7b-021b-4de7-940a-170e315ad915" xlink:href="https://xbrl.fasb.org/us-gaap/2023/elts/us-gaap-2023.xsd#us-gaap_SeriesAPreferredStockMember"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_us-gaap_ClassOfStockDomain_eec33fe3-138c-4219-aae6-c8451a04143e" xlink:to="loc_us-gaap_SeriesAPreferredStockMember_d6145b7b-021b-4de7-940a-170e315ad915" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentType_69ef6a13-418a-46c3-a926-a688bea4f77e" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_DocumentType"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_DocumentInformationLineItems_4bba68f4-c312-42f7-a6f2-6b1561c54299" xlink:to="loc_dei_DocumentType_69ef6a13-418a-46c3-a926-a688bea4f77e" xlink:type="arc" order="0"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentPeriodEndDate_3d894853-ca71-4dc0-b9e6-82e0f6d74a6b" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_DocumentPeriodEndDate"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_DocumentInformationLineItems_4bba68f4-c312-42f7-a6f2-6b1561c54299" xlink:to="loc_dei_DocumentPeriodEndDate_3d894853-ca71-4dc0-b9e6-82e0f6d74a6b" xlink:type="arc" order="1"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityRegistrantName_95b5e037-b922-4df8-88fc-237ee2c919bc" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityRegistrantName"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_DocumentInformationLineItems_4bba68f4-c312-42f7-a6f2-6b1561c54299" xlink:to="loc_dei_EntityRegistrantName_95b5e037-b922-4df8-88fc-237ee2c919bc" xlink:type="arc" order="2"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityCentralIndexKey_5ae71f91-859b-44fa-856c-faac52c80f78" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityCentralIndexKey"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_DocumentInformationLineItems_4bba68f4-c312-42f7-a6f2-6b1561c54299" xlink:to="loc_dei_EntityCentralIndexKey_5ae71f91-859b-44fa-856c-faac52c80f78" xlink:type="arc" order="3"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_AmendmentFlag_ebb0c8fe-0b41-431f-9f4e-84ca7bbd0a50" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_AmendmentFlag"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_DocumentInformationLineItems_4bba68f4-c312-42f7-a6f2-6b1561c54299" xlink:to="loc_dei_AmendmentFlag_ebb0c8fe-0b41-431f-9f4e-84ca7bbd0a50" xlink:type="arc" order="4"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityIncorporationStateCountryCode_3b94d8b6-95c0-45b4-8255-7dd86cd9387c" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityIncorporationStateCountryCode"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_DocumentInformationLineItems_4bba68f4-c312-42f7-a6f2-6b1561c54299" xlink:to="loc_dei_EntityIncorporationStateCountryCode_3b94d8b6-95c0-45b4-8255-7dd86cd9387c" xlink:type="arc" order="5"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityFileNumber_196d4cbb-921d-47e9-a986-9f444df62a6d" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityFileNumber"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_DocumentInformationLineItems_4bba68f4-c312-42f7-a6f2-6b1561c54299" xlink:to="loc_dei_EntityFileNumber_196d4cbb-921d-47e9-a986-9f444df62a6d" xlink:type="arc" order="6"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityTaxIdentificationNumber_a2b3c472-de11-4109-a137-cb09d3387d5a" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityTaxIdentificationNumber"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_DocumentInformationLineItems_4bba68f4-c312-42f7-a6f2-6b1561c54299" xlink:to="loc_dei_EntityTaxIdentificationNumber_a2b3c472-de11-4109-a137-cb09d3387d5a" xlink:type="arc" order="7"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressAddressLine2_493c2e81-d896-4127-8671-a042e737715a" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityAddressAddressLine2"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_DocumentInformationLineItems_4bba68f4-c312-42f7-a6f2-6b1561c54299" xlink:to="loc_dei_EntityAddressAddressLine2_493c2e81-d896-4127-8671-a042e737715a" xlink:type="arc" order="8"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressAddressLine1_8c99c972-a3bd-47e1-a629-35cf61c24998" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityAddressAddressLine1"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_DocumentInformationLineItems_4bba68f4-c312-42f7-a6f2-6b1561c54299" xlink:to="loc_dei_EntityAddressAddressLine1_8c99c972-a3bd-47e1-a629-35cf61c24998" xlink:type="arc" order="9"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressCityOrTown_b065d833-0b57-4fa4-9a82-bc172068ae5f" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityAddressCityOrTown"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_DocumentInformationLineItems_4bba68f4-c312-42f7-a6f2-6b1561c54299" xlink:to="loc_dei_EntityAddressCityOrTown_b065d833-0b57-4fa4-9a82-bc172068ae5f" xlink:type="arc" order="10"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressStateOrProvince_77fd73a3-1e03-4063-82f3-f616bba8a4b8" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityAddressStateOrProvince"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_DocumentInformationLineItems_4bba68f4-c312-42f7-a6f2-6b1561c54299" xlink:to="loc_dei_EntityAddressStateOrProvince_77fd73a3-1e03-4063-82f3-f616bba8a4b8" xlink:type="arc" order="11"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressPostalZipCode_dfb7ff83-efe9-4c0d-99cf-3d8a0d6e6057" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityAddressPostalZipCode"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_DocumentInformationLineItems_4bba68f4-c312-42f7-a6f2-6b1561c54299" xlink:to="loc_dei_EntityAddressPostalZipCode_dfb7ff83-efe9-4c0d-99cf-3d8a0d6e6057" xlink:type="arc" order="12"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_CityAreaCode_a30c5fd7-4629-4c47-bf3a-8b8a31da1fa3" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_CityAreaCode"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_DocumentInformationLineItems_4bba68f4-c312-42f7-a6f2-6b1561c54299" xlink:to="loc_dei_CityAreaCode_a30c5fd7-4629-4c47-bf3a-8b8a31da1fa3" xlink:type="arc" order="13"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_LocalPhoneNumber_a89b75c9-10c2-4093-a2fd-a6fb2584bbe3" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_LocalPhoneNumber"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_DocumentInformationLineItems_4bba68f4-c312-42f7-a6f2-6b1561c54299" xlink:to="loc_dei_LocalPhoneNumber_a89b75c9-10c2-4093-a2fd-a6fb2584bbe3" xlink:type="arc" order="14"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_WrittenCommunications_08b90660-5fda-4f2e-92cd-33f1b10dae2d" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_WrittenCommunications"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_DocumentInformationLineItems_4bba68f4-c312-42f7-a6f2-6b1561c54299" xlink:to="loc_dei_WrittenCommunications_08b90660-5fda-4f2e-92cd-33f1b10dae2d" xlink:type="arc" order="15"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_SolicitingMaterial_10160e40-a53b-4c5c-9aca-a0df1b5b5c5c" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_SolicitingMaterial"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_DocumentInformationLineItems_4bba68f4-c312-42f7-a6f2-6b1561c54299" xlink:to="loc_dei_SolicitingMaterial_10160e40-a53b-4c5c-9aca-a0df1b5b5c5c" xlink:type="arc" order="16"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_PreCommencementTenderOffer_85180600-471b-4a6f-a007-0b0cfccb69f3" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_PreCommencementTenderOffer"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_DocumentInformationLineItems_4bba68f4-c312-42f7-a6f2-6b1561c54299" xlink:to="loc_dei_PreCommencementTenderOffer_85180600-471b-4a6f-a007-0b0cfccb69f3" xlink:type="arc" order="17"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_PreCommencementIssuerTenderOffer_d7914c6b-6a03-49a9-959c-8affb740cb2f" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_PreCommencementIssuerTenderOffer"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_DocumentInformationLineItems_4bba68f4-c312-42f7-a6f2-6b1561c54299" xlink:to="loc_dei_PreCommencementIssuerTenderOffer_d7914c6b-6a03-49a9-959c-8affb740cb2f" xlink:type="arc" order="18"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_Security12bTitle_7b57ad2b-a3c0-4fc0-8849-bce05cd59851" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_Security12bTitle"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_DocumentInformationLineItems_4bba68f4-c312-42f7-a6f2-6b1561c54299" xlink:to="loc_dei_Security12bTitle_7b57ad2b-a3c0-4fc0-8849-bce05cd59851" xlink:type="arc" order="19"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_TradingSymbol_9bbc146e-16ab-421b-a715-37b4b6f74b0e" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_TradingSymbol"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_DocumentInformationLineItems_4bba68f4-c312-42f7-a6f2-6b1561c54299" xlink:to="loc_dei_TradingSymbol_9bbc146e-16ab-421b-a715-37b4b6f74b0e" xlink:type="arc" order="20"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_SecurityExchangeName_4426f444-4e81-44da-adfd-cc8007202b10" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_SecurityExchangeName"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_DocumentInformationLineItems_4bba68f4-c312-42f7-a6f2-6b1561c54299" xlink:to="loc_dei_SecurityExchangeName_4426f444-4e81-44da-adfd-cc8007202b10" xlink:type="arc" order="21"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityEmergingGrowthCompany_bfcb99bc-9a4c-4845-8777-d3876315de8e" xlink:href="https://xbrl.sec.gov/dei/2023/dei-2023.xsd#dei_EntityEmergingGrowthCompany"/>
    <link:definitionArc xlink:arcrole="http://xbrl.org/int/dim/arcrole/domain-member" xlink:from="loc_dei_DocumentInformationLineItems_4bba68f4-c312-42f7-a6f2-6b1561c54299" xlink:to="loc_dei_EntityEmergingGrowthCompany_bfcb99bc-9a4c-4845-8777-d3876315de8e" xlink:type="arc" order="22"/>
  </link:definitionLink>
</link:linkbase>
