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Business Combinations (Details Textual) (USD $) | 12 Months Ended | 1 Months Ended | 12 Months Ended |  | 12 Months Ended |
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Dec. 31, 2013 | Dec. 31, 2012 | Dec. 31, 2011 | Jan. 31, 2011 CyDex medication licensee product | Dec. 31, 2013 CyDex employee_equivalent | Dec. 31, 2012 CyDex | Jan. 31, 2011 CyDex Complete technology | Jan. 31, 2011 CyDex Trademark and trade name | Dec. 31, 2013 CyDex Customer relationships | Jan. 31, 2011 CyDex Customer relationships
Business Acquisition [Line Items] |  |  |  |  |  |  |  |  |  |
Number of FDA-approved medications |  |  |  | 6 |  |  |  |  |  |
Number of licensees |  |  |  | 4 |  |  |  |  |  |
Cash paid to CyDex shareholders |  |  |  | $ 31,572,000 |  |  |  |  |  |
Percentage of related revenue |  |  |  |  | 20.00% |  |  |  |  |
Amount exceeds to get related revenue for CyDex share holders |  |  |  |  | 15,000,000 |  |  |  |  |
Percentage of related revenue additional |  |  |  |  | 10.00% |  |  |  |  |
Aggregate CyDex-related revenue |  |  |  |  | 35,000,000 |  |  |  |  |
Discount rate used to estimate future cash flows |  |  |  | 21.50% |  |  | 20.50% | 20.50% |  | 21.50%
Gain (loss) on asset disposal | 5,000 | (17,000) | (456,000) |  | 500,000 | 0 |  |  |  |
Number of employees required |  |  |  |  | 5 |  |  |  |  |
Investments for acquiring employees |  |  |  |  | 1,500,000 |  |  |  |  |
Business combination, weighted-average amortizaiton period intangible assets |  |  |  |  | 20 years |  |  |  | 20 years |
In-process research and development |  |  |  | $ 3,200,000 |  |  |  |  |  |
Number of acquirees in-process research and development products |  |  |  | 2 |  |  |  |  |  |

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