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Segment Reporting (Details) (USD $)
In Thousands, unless otherwise specified
 3 Months Ended 12 Months Ended
Dec. 31, 2013
Sep. 30, 2013
Jun. 30, 2013
Mar. 31, 2013
Dec. 31, 2012
Sep. 30, 2012
Jun. 30, 2012
Mar. 31, 2012
Dec. 31, 2013
Dec. 31, 2012
Dec. 31, 2011
Summary of segment information                      
Total Assets $ 104,713       $ 104,260       $ 104,713 $ 104,260  
Net revenues from external customers 14,737 13,005 9,580 11,651 13,635 6,375 5,742 5,636 48,973 31,388 30,037
Operating income                 14,943 193 (878)
Depreciation and amortization expense                 2,663 2,727 2,790
Write-off of in-process research and development                 480    
Income tax expense (138) (60) (110) (66) 1,636 (142) (338) 35 (374) 1,191 13,270
Interest expense, net                 2,077 2,924  
Gain on sale of Avinza Product Line before income taxes                 2,588 3,656  
Income tax expense from discontinuing operations                   (1,509)  
Ligand
                      
Summary of segment information                      
Total Assets 38,408       28,731       38,408 28,731  
Net revenues from external customers                 21,436 19,582  
Operating income                 253 (919)  
Depreciation and amortization expense                 233 222  
Write-off of in-process research and development                 0    
Income tax expense                 (419) 1,096  
Interest expense, net                 2,077 2,924  
Gain on sale of Avinza Product Line before income taxes                 2,588 3,656  
Income tax expense from discontinuing operations                   (1,509)  
CyDex
                      
Summary of segment information                      
Total Assets 66,305       75,529       66,305 75,529  
Net revenues from external customers                 27,537 11,806  
Operating income                 14,690 1,112  
Depreciation and amortization expense                 2,430 2,505  
Write-off of in-process research and development                 480    
Income tax expense                 45 95  
Interest expense, net                 0 0  
Gain on sale of Avinza Product Line before income taxes                 0 0  
Income tax expense from discontinuing operations                   $ 0