Financial Instruments (Fair Value Measurements) (Details) (Recurring, USD $) In Thousands, unless otherwise specified	Jun. 30, 2014	Dec. 31, 2013
Assets:
Assets, fair value	$ 9,555	$ 17,427
Liabilities:
Liabilities, fair value	16,981	25,904
Current portion of contingent liabilities-CyDex
Liabilities:
Liabilities, fair value	2,877	1,712
Current portion of co-promote termination liability
Liabilities:
Liabilities, fair value	391	4,329
Long-term portion of contingent liabilities-Metabasis
Liabilities:
Liabilities, fair value	4,724	4,196
Long-term portion of contingent liabilities-CyDex
Liabilities:
Liabilities, fair value	7,498	7,599
Liability for short-term investments owed to former licensees
Liabilities:
Liabilities, fair value	1,078	651
Long-term portion of co-promote termination liability
Liabilities:
Liabilities, fair value	413	7,417
Current portion of co-promote termination payments receivable
Assets:
Assets, fair value	391	4,329
Available-for-sale securities
Assets:
Assets, fair value	7,490	4,340
Restricted cash and investments
Assets:
Assets, fair value	1,261	1,341
Long-term portion of co-promote termination payments receivable
Assets:
Assets, fair value	413	7,417
Quoted Prices in Active Markets for Identical Assets (Level 1)
Assets:
Assets, fair value	7,490	4,340
Liabilities:
Liabilities, fair value	5,802	4,847
Quoted Prices in Active Markets for Identical Assets (Level 1) \| Current portion of contingent liabilities-CyDex
Liabilities:
Liabilities, fair value	0	0
Quoted Prices in Active Markets for Identical Assets (Level 1) \| Current portion of co-promote termination liability
Liabilities:
Liabilities, fair value	0	0
Quoted Prices in Active Markets for Identical Assets (Level 1) \| Long-term portion of contingent liabilities-Metabasis
Liabilities:
Liabilities, fair value	4,724	4,196
Quoted Prices in Active Markets for Identical Assets (Level 1) \| Long-term portion of contingent liabilities-CyDex
Liabilities:
Liabilities, fair value	0	0
Quoted Prices in Active Markets for Identical Assets (Level 1) \| Liability for short-term investments owed to former licensees
Liabilities:
Liabilities, fair value	1,078	651
Quoted Prices in Active Markets for Identical Assets (Level 1) \| Long-term portion of co-promote termination liability
Liabilities:
Liabilities, fair value	0	0
Quoted Prices in Active Markets for Identical Assets (Level 1) \| Current portion of co-promote termination payments receivable
Assets:
Assets, fair value	0	0
Quoted Prices in Active Markets for Identical Assets (Level 1) \| Available-for-sale securities
Assets:
Assets, fair value	7,490	4,340
Quoted Prices in Active Markets for Identical Assets (Level 1) \| Restricted cash and investments
Assets:
Assets, fair value	0	0
Quoted Prices in Active Markets for Identical Assets (Level 1) \| Long-term portion of co-promote termination payments receivable
Assets:
Assets, fair value	0	0
Significant Other Observable Inputs (Level 2)
Assets:
Assets, fair value	1,261	1,341
Liabilities:
Liabilities, fair value	0	0
Significant Other Observable Inputs (Level 2) \| Current portion of contingent liabilities-CyDex
Liabilities:
Liabilities, fair value	0	0
Significant Other Observable Inputs (Level 2) \| Current portion of co-promote termination liability
Liabilities:
Liabilities, fair value	0	0
Significant Other Observable Inputs (Level 2) \| Long-term portion of contingent liabilities-Metabasis
Liabilities:
Liabilities, fair value	0	0
Significant Other Observable Inputs (Level 2) \| Long-term portion of contingent liabilities-CyDex
Liabilities:
Liabilities, fair value	0	0
Significant Other Observable Inputs (Level 2) \| Liability for short-term investments owed to former licensees
Liabilities:
Liabilities, fair value	0	0
Significant Other Observable Inputs (Level 2) \| Long-term portion of co-promote termination liability
Liabilities:
Liabilities, fair value	0	0
Significant Other Observable Inputs (Level 2) \| Current portion of co-promote termination payments receivable
Assets:
Assets, fair value	0	0
Significant Other Observable Inputs (Level 2) \| Available-for-sale securities
Assets:
Assets, fair value	0	0
Significant Other Observable Inputs (Level 2) \| Restricted cash and investments
Assets:
Assets, fair value	1,261	1,341
Significant Other Observable Inputs (Level 2) \| Long-term portion of co-promote termination payments receivable
Assets:
Assets, fair value	0	0
Significant Unobservable Inputs (Level 3)
Assets:
Assets, fair value	804	11,746
Liabilities:
Liabilities, fair value	11,179	21,057
Significant Unobservable Inputs (Level 3) \| Current portion of contingent liabilities-CyDex
Liabilities:
Liabilities, fair value	2,877	1,712
Significant Unobservable Inputs (Level 3) \| Current portion of co-promote termination liability
Liabilities:
Liabilities, fair value	391	4,329
Significant Unobservable Inputs (Level 3) \| Long-term portion of contingent liabilities-Metabasis
Liabilities:
Liabilities, fair value	0	0
Significant Unobservable Inputs (Level 3) \| Long-term portion of contingent liabilities-CyDex
Liabilities:
Liabilities, fair value	7,498	7,599
Significant Unobservable Inputs (Level 3) \| Liability for short-term investments owed to former licensees
Liabilities:
Liabilities, fair value	0	0
Significant Unobservable Inputs (Level 3) \| Long-term portion of co-promote termination liability
Liabilities:
Liabilities, fair value	413	7,417
Significant Unobservable Inputs (Level 3) \| Current portion of co-promote termination payments receivable
Assets:
Assets, fair value	391	4,329
Significant Unobservable Inputs (Level 3) \| Available-for-sale securities
Assets:
Assets, fair value	0	0
Significant Unobservable Inputs (Level 3) \| Restricted cash and investments
Assets:
Assets, fair value	0	0
Significant Unobservable Inputs (Level 3) \| Long-term portion of co-promote termination payments receivable
Assets:
Assets, fair value	$ 413	$ 7,417