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Condensed Consolidated Statements of Operations (USD $)
In Thousands, except Share data, unless otherwise specified
 3 Months Ended 6 Months Ended
Jun. 30, 2014
Jun. 30, 2013
Jun. 30, 2014
Jun. 30, 2013
Revenues:        
Royalties $ 5,241 $ 4,916 $ 13,091 $ 10,742
Material sales 3,476 3,993 9,191 5,532
Collaborative research and development and other revenues 1,891 671 4,284 4,957
Total revenues 10,608 9,580 26,566 21,231
Operating costs and expenses:        
Cost of sales 1,186 1,214 3,637 1,877
Research and development 2,689 2,022 5,821 4,487
General and administrative 5,239 4,306 10,310 8,808
Lease exit and termination costs 136 44 340 132
Write-off of in-process research and development 0 480 0 480
Total operating costs and expenses 9,250 8,066 20,108 15,784
Income from operations 1,358 1,514 6,458 5,447
Other (expense) income:        
Interest expense, net (181) (453) (429) (1,361)
(Increase) decrease in contingent liabilities (1,312) 2,741 (3,260) 900
Other, net 1,376 2 621 188
Total other (expense) income, net (117) 2,290 (3,068) (273)
Income before income taxes 1,241 3,804 3,390 5,174
Income tax benefit (expense) 47 (110) (6) (176)
Income from continuing operations 1,288 3,694 3,384 4,998
Discontinued operations:        
Gain on sale of Avinza Product Line before income taxes 0 2,397 0 2,588
Income from discontinued operations 0 2,397 0 2,588
Net income: 1,288 6,091 3,384 7,586
Less: Net loss attributable to noncontrolling interests (304) 0 (304) 0
Net income: $ 1,592 $ 6,091 $ 3,688 $ 7,586
Basic per share amounts:        
Income (loss) from continuing operations (in usd per share) $ 0.08 $ 0.18 $ 0.18 $ 0.25
Income from discontinued operations (in usd per share) $ 0.00 $ 0.12 $ 0.00 $ 0.13
Net income (loss) (in usd per share) $ 0.08 $ 0.30 $ 0.18 $ 0.38
Diluted per share amounts:        
Income (loss) from continuing operations (in usd per share) $ 0.07 $ 0.18 $ 0.17 $ 0.24
Income from discontinued operations (in usd per share) $ 0.00 $ 0.12 $ 0.00 $ 0.13
Net income (loss) (in usd per share) $ 0.07 $ 0.30 $ 0.17 $ 0.37
Weighted average number of common shares-basic (in shares) 20,738,299 20,258,618 20,668,110 20,223,634
Weighted average number of common shares-diluted (in shares) 21,780,034 20,427,360 21,776,125 20,277,763