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Basis of Presentation (Details 2) (USD $)
In Thousands, unless otherwise specified
Dec. 31, 2014
Dec. 31, 2013
Summary of Property and equipment    
Property and equipment , gross $ 3,129us-gaap_PropertyPlantAndEquipmentGross $ 4,740us-gaap_PropertyPlantAndEquipmentGross
Less accumulated depreciation and amortization (2,643)us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment (3,873)us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment
Property and equipment, net 486us-gaap_PropertyPlantAndEquipmentNet 867us-gaap_PropertyPlantAndEquipmentNet
Lab and office equipment    
Summary of Property and equipment    
Property and equipment , gross 2,232us-gaap_PropertyPlantAndEquipmentGross
/ us-gaap_PropertyPlantAndEquipmentByTypeAxis
= us-gaap_OfficeEquipmentMember
3,737us-gaap_PropertyPlantAndEquipmentGross
/ us-gaap_PropertyPlantAndEquipmentByTypeAxis
= us-gaap_OfficeEquipmentMember
Leasehold improvements    
Summary of Property and equipment    
Property and equipment , gross 273us-gaap_PropertyPlantAndEquipmentGross
/ us-gaap_PropertyPlantAndEquipmentByTypeAxis
= us-gaap_LeaseholdImprovementsMember
387us-gaap_PropertyPlantAndEquipmentGross
/ us-gaap_PropertyPlantAndEquipmentByTypeAxis
= us-gaap_LeaseholdImprovementsMember
Computer equipment and software    
Summary of Property and equipment    
Property and equipment , gross $ 624us-gaap_PropertyPlantAndEquipmentGross
/ us-gaap_PropertyPlantAndEquipmentByTypeAxis
= lgnd_ComputerEquipmentAndSoftwareMember
$ 616us-gaap_PropertyPlantAndEquipmentGross
/ us-gaap_PropertyPlantAndEquipmentByTypeAxis
= lgnd_ComputerEquipmentAndSoftwareMember