CONSOLIDATED STATEMENTS OF OPERATIONS (USD $) In Thousands, except Share data, unless otherwise specified	12 Months Ended
Dec. 31, 2014	Dec. 31, 2013	Dec. 31, 2012
Revenues:
Royalties	$ 29,994us-gaap_RoyaltyRevenue	$ 23,584us-gaap_RoyaltyRevenue	$ 14,073us-gaap_RoyaltyRevenue
Material Sales	28,488us-gaap_SalesRevenueGoodsNet	19,072us-gaap_SalesRevenueGoodsNet	9,432us-gaap_SalesRevenueGoodsNet
Collaborative research and development and other revenues	6,056	6,317	7,883
Total revenues	64,538us-gaap_Revenues	48,973us-gaap_Revenues	31,388us-gaap_Revenues
Operating costs and expenses:
Cost of material sales	9,136us-gaap_CostOfGoodsSold	5,732us-gaap_CostOfGoodsSold	3,601us-gaap_CostOfGoodsSold
Research and development	12,122us-gaap_ResearchAndDevelopmentExpense	9,274us-gaap_ResearchAndDevelopmentExpense	10,790us-gaap_ResearchAndDevelopmentExpense
General and administrative	22,570us-gaap_GeneralAndAdministrativeExpense	17,984us-gaap_GeneralAndAdministrativeExpense	15,782us-gaap_GeneralAndAdministrativeExpense
Lease exit and termination costs	1,084us-gaap_BusinessExitCosts1	560us-gaap_BusinessExitCosts1	1,022us-gaap_BusinessExitCosts1
Write-off of acquired in-process research and development	0us-gaap_ResearchAndDevelopmentInProcess	480us-gaap_ResearchAndDevelopmentInProcess	0us-gaap_ResearchAndDevelopmentInProcess
Total operating costs and expenses	44,912us-gaap_OperatingCostsAndExpenses	34,030us-gaap_OperatingCostsAndExpenses	31,195us-gaap_OperatingCostsAndExpenses
Income from operations	19,626us-gaap_OperatingIncomeLoss	14,943us-gaap_OperatingIncomeLoss	193us-gaap_OperatingIncomeLoss
Other (expense) income:
Interest expense, net	(4,860)us-gaap_InterestIncomeExpenseNet	(2,077)us-gaap_InterestIncomeExpenseNet	(2,924)us-gaap_InterestIncomeExpenseNet
Increase in contingent liabilities	(5,135)	(3,597)	(1,650)
Other, net	1,671us-gaap_OtherNonoperatingIncomeExpense	(63)us-gaap_OtherNonoperatingIncomeExpense	516us-gaap_OtherNonoperatingIncomeExpense
Total other expense, net	(8,324)us-gaap_NonoperatingIncomeExpense	(5,737)us-gaap_NonoperatingIncomeExpense	(4,058)us-gaap_NonoperatingIncomeExpense
Income (loss) from continuing operations before income tax benefit	11,302	9,206	(3,865)
Income tax (expense) benefit from continuing operations	(410)us-gaap_IncomeTaxExpenseBenefit	(374)us-gaap_IncomeTaxExpenseBenefit	1,191us-gaap_IncomeTaxExpenseBenefit
Income (loss) from continuing operations including noncontrolling interests	10,892	8,832	(2,674)
Less: Net loss attributable to noncontrolling interests	(1,132)	0	0
Net income (loss) from continuing operations	12,024	8,832	(2,674)
Discontinued operations:
Gain on sale of Avinza Product Line, net	0	2,588	3,656
Income tax expense on discontinued operations	0	0	(1,509)
Income from discontinued operations	0	2,588	2,147
Net income	$ 12,024us-gaap_NetIncomeLoss	$ 11,420us-gaap_NetIncomeLoss	$ (527)us-gaap_NetIncomeLoss
Basic per share amounts:
Income (loss) from continuing operations (in usd per share)	$ 0.59	$ 0.43	$ (0.14)
Income from discontinued operations (in usd per share)	$ 0.00	$ 0.13	$ 0.11
Net income (loss) (in usd per share)	$ 0.59us-gaap_EarningsPerShareBasic	$ 0.56us-gaap_EarningsPerShareBasic	$ (0.03)us-gaap_EarningsPerShareBasic
Weighted average number of common shares-basic	20,418,569	20,312,395	19,853,095
Diluted per share amounts:
Income (loss) from continuing operations (in usd per share)	$ 0.56	$ 0.43	$ (0.14)
Income from discontinued operations (in usd per share)	$ 0.00	$ 0.12	$ 0.11
Net income (loss) (in usd per share)	$ 0.56us-gaap_EarningsPerShareDiluted	$ 0.55us-gaap_EarningsPerShareDiluted	$ (0.03)us-gaap_EarningsPerShareDiluted
Weighted average number of common shares-diluted	21,433,177	20,745,454	19,853,095

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