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CONSOLIDATED STATEMENT OF STOCKHOLDERS' EQUITY (DEFICIT) (USD $) In Thousands, except Share data, unless otherwise specified	Total	Common Stock	Additional paid-in capital	Accumulated other comprehensive income (loss)	Accumulated deficit	Noncontrolling interest	Treasury stock
Balance at beginning of period at Dec. 31, 2011	$ 8,185us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest	$ 21us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest / us-gaap_StatementEquityComponentsAxis = us-gaap_CommonStockMember	$ 732,676us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest / us-gaap_StatementEquityComponentsAxis = us-gaap_AdditionalPaidInCapitalMember	$ 0us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest / us-gaap_StatementEquityComponentsAxis = us-gaap_AccumulatedOtherComprehensiveIncomeMember	$ (682,232)us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest / us-gaap_StatementEquityComponentsAxis = us-gaap_RetainedEarningsMember		$ (42,280)us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest / us-gaap_StatementEquityComponentsAxis = us-gaap_TreasuryStockMember
Balance at beginning of period (in shares) at Dec. 31, 2011		20,682,506us-gaap_SharesOutstanding / us-gaap_StatementEquityComponentsAxis = us-gaap_CommonStockMember					(1,118,222)us-gaap_SharesOutstanding / us-gaap_StatementEquityComponentsAxis = us-gaap_TreasuryStockMember
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of common stock under employee stock compensation plans, net	1,103us-gaap_StockIssuedDuringPeriodValueEmployeeStockPurchasePlan		1,103us-gaap_StockIssuedDuringPeriodValueEmployeeStockPurchasePlan / us-gaap_StatementEquityComponentsAxis = us-gaap_AdditionalPaidInCapitalMember
Issuance of common stock under employee stock compensation plans (in shares)		180,979us-gaap_StockIssuedDuringPeriodSharesEmployeeStockPurchasePlans / us-gaap_StatementEquityComponentsAxis = us-gaap_CommonStockMember
Issuance of common stock, net	5,313us-gaap_StockIssuedDuringPeriodValueNewIssues		5,313us-gaap_StockIssuedDuringPeriodValueNewIssues / us-gaap_StatementEquityComponentsAxis = us-gaap_AdditionalPaidInCapitalMember
Issuance of common stock, net (in shares)		302,750us-gaap_StockIssuedDuringPeriodSharesNewIssues / us-gaap_StatementEquityComponentsAxis = us-gaap_CommonStockMember
Stock-based compensation	4,067us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue		4,067us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue / us-gaap_StatementEquityComponentsAxis = us-gaap_AdditionalPaidInCapitalMember
Shares released from restriction	8,344us-gaap_StockIssuedDuringPeriodValueRestrictedStockAwardNetOfForfeitures		8,344us-gaap_StockIssuedDuringPeriodValueRestrictedStockAwardNetOfForfeitures / us-gaap_StatementEquityComponentsAxis = us-gaap_AdditionalPaidInCapitalMember
Shares released from restriction (in shares)		112,371us-gaap_StockIssuedDuringPeriodSharesRestrictedStockAwardNetOfForfeitures / us-gaap_StatementEquityComponentsAxis = us-gaap_CommonStockMember
Net income (loss)	(527)us-gaap_NetIncomeLoss				(527)us-gaap_NetIncomeLoss / us-gaap_StatementEquityComponentsAxis = us-gaap_RetainedEarningsMember
Net loss in noncontrolling interests	0us-gaap_NetIncomeLossAttributableToNoncontrollingInterest
Realized gain on sale of investments	0us-gaap_OtherComprehensiveIncomeLossReclassificationAdjustmentFromAOCIForSaleOfSecuritiesNetOfTax
Balance at end of period at Dec. 31, 2012	26,485us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest	21us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest / us-gaap_StatementEquityComponentsAxis = us-gaap_CommonStockMember	751,503us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest / us-gaap_StatementEquityComponentsAxis = us-gaap_AdditionalPaidInCapitalMember	0us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest / us-gaap_StatementEquityComponentsAxis = us-gaap_AccumulatedOtherComprehensiveIncomeMember	(682,759)us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest / us-gaap_StatementEquityComponentsAxis = us-gaap_RetainedEarningsMember		(42,280)us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest / us-gaap_StatementEquityComponentsAxis = us-gaap_TreasuryStockMember
Balance at end of period (in shares) at Dec. 31, 2012		21,278,606us-gaap_SharesOutstanding / us-gaap_StatementEquityComponentsAxis = us-gaap_CommonStockMember					(1,118,222)us-gaap_SharesOutstanding / us-gaap_StatementEquityComponentsAxis = us-gaap_TreasuryStockMember
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Issuance of common stock under employee stock compensation plans, net	3,128us-gaap_StockIssuedDuringPeriodValueEmployeeStockPurchasePlan	1us-gaap_StockIssuedDuringPeriodValueEmployeeStockPurchasePlan / us-gaap_StatementEquityComponentsAxis = us-gaap_CommonStockMember	3,127us-gaap_StockIssuedDuringPeriodValueEmployeeStockPurchasePlan / us-gaap_StatementEquityComponentsAxis = us-gaap_AdditionalPaidInCapitalMember
Issuance of common stock under employee stock compensation plans (in shares)		308,137us-gaap_StockIssuedDuringPeriodSharesEmployeeStockPurchasePlans / us-gaap_StatementEquityComponentsAxis = us-gaap_CommonStockMember
Stock-based compensation	5,666us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue		5,666us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue / us-gaap_StatementEquityComponentsAxis = us-gaap_AdditionalPaidInCapitalMember
Shares released from restriction	0us-gaap_StockIssuedDuringPeriodValueRestrictedStockAwardNetOfForfeitures
Retirement of treasury shares (in shares)	(1,118,222)us-gaap_TreasuryStockSharesRetired	(1,118,222)us-gaap_TreasuryStockSharesRetired / us-gaap_StatementEquityComponentsAxis = us-gaap_CommonStockMember					1,118,222us-gaap_TreasuryStockSharesRetired / us-gaap_StatementEquityComponentsAxis = us-gaap_TreasuryStockMember
Retirement of treasury shares		(1)us-gaap_TreasuryStockRetiredCostMethodAmount / us-gaap_StatementEquityComponentsAxis = us-gaap_CommonStockMember	(42,279)us-gaap_TreasuryStockRetiredCostMethodAmount / us-gaap_StatementEquityComponentsAxis = us-gaap_AdditionalPaidInCapitalMember				42,280us-gaap_TreasuryStockRetiredCostMethodAmount / us-gaap_StatementEquityComponentsAxis = us-gaap_TreasuryStockMember
Unrealized net loss on available-for-sale securities	2,914us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax			2,914us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax / us-gaap_StatementEquityComponentsAxis = us-gaap_AccumulatedOtherComprehensiveIncomeMember
Net income (loss)	11,420us-gaap_NetIncomeLoss				11,420us-gaap_NetIncomeLoss / us-gaap_StatementEquityComponentsAxis = us-gaap_RetainedEarningsMember
Net loss in noncontrolling interests	0us-gaap_NetIncomeLossAttributableToNoncontrollingInterest
Realized gain on sale of investments	0us-gaap_OtherComprehensiveIncomeLossReclassificationAdjustmentFromAOCIForSaleOfSecuritiesNetOfTax
Balance at end of period at Dec. 31, 2013	49,613us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest	21us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest / us-gaap_StatementEquityComponentsAxis = us-gaap_CommonStockMember	718,017us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest / us-gaap_StatementEquityComponentsAxis = us-gaap_AdditionalPaidInCapitalMember	2,914us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest / us-gaap_StatementEquityComponentsAxis = us-gaap_AccumulatedOtherComprehensiveIncomeMember	(671,339)us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest / us-gaap_StatementEquityComponentsAxis = us-gaap_RetainedEarningsMember		0us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest / us-gaap_StatementEquityComponentsAxis = us-gaap_TreasuryStockMember
Balance at end of period (in shares) at Dec. 31, 2013		20,468,521us-gaap_SharesOutstanding / us-gaap_StatementEquityComponentsAxis = us-gaap_CommonStockMember					0us-gaap_SharesOutstanding / us-gaap_StatementEquityComponentsAxis = us-gaap_TreasuryStockMember
Increase (Decrease) in Stockholders' Equity [Roll Forward]
Consolidation of variable interest entity	(778)us-gaap_VariableInterestEntityInitialConsolidationGainOrLoss					(778)us-gaap_VariableInterestEntityInitialConsolidationGainOrLoss / us-gaap_StatementEquityComponentsAxis = us-gaap_NoncontrollingInterestMember
Issuance of common stock under employee stock compensation plans, net	4,561us-gaap_StockIssuedDuringPeriodValueEmployeeStockPurchasePlan		4,561us-gaap_StockIssuedDuringPeriodValueEmployeeStockPurchasePlan / us-gaap_StatementEquityComponentsAxis = us-gaap_AdditionalPaidInCapitalMember
Issuance of common stock under employee stock compensation plans (in shares)		360,054us-gaap_StockIssuedDuringPeriodSharesEmployeeStockPurchasePlans / us-gaap_StatementEquityComponentsAxis = us-gaap_CommonStockMember
Stock-based compensation	11,270us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue		11,270us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue / us-gaap_StatementEquityComponentsAxis = us-gaap_AdditionalPaidInCapitalMember
Shares released from restriction	0us-gaap_StockIssuedDuringPeriodValueRestrictedStockAwardNetOfForfeitures
Unrealized net loss on available-for-sale securities	3,872us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax			3,872us-gaap_OtherComprehensiveIncomeUnrealizedHoldingGainLossOnSecuritiesArisingDuringPeriodNetOfTax / us-gaap_StatementEquityComponentsAxis = us-gaap_AccumulatedOtherComprehensiveIncomeMember
Repurchase of common stock	(67,955)us-gaap_StockRepurchasedDuringPeriodValue	(1)us-gaap_StockRepurchasedDuringPeriodValue / us-gaap_StatementEquityComponentsAxis = us-gaap_CommonStockMember	(67,954)us-gaap_StockRepurchasedDuringPeriodValue / us-gaap_StatementEquityComponentsAxis = us-gaap_AdditionalPaidInCapitalMember
Repurchase of common stock (in shares)	(1,253,425)us-gaap_StockRepurchasedDuringPeriodShares	(1,253,425)us-gaap_StockRepurchasedDuringPeriodShares / us-gaap_StatementEquityComponentsAxis = us-gaap_CommonStockMember
Sale of warrants	11,638us-gaap_AdjustmentsToAdditionalPaidInCapitalWarrantIssued		11,638us-gaap_AdjustmentsToAdditionalPaidInCapitalWarrantIssued / us-gaap_StatementEquityComponentsAxis = us-gaap_AdditionalPaidInCapitalMember
Purchase of convertible bond hedge	(48,143)lgnd_AdjustmentsToAdditionalPaidInCapitalDerivativeHedgeOnConvertibleBond		(48,143)lgnd_AdjustmentsToAdditionalPaidInCapitalDerivativeHedgeOnConvertibleBond / us-gaap_StatementEquityComponentsAxis = us-gaap_AdditionalPaidInCapitalMember
Equity component of convertible debt issuance, net of issuance costs	51,271us-gaap_AdjustmentsToAdditionalPaidInCapitalEquityComponentOfConvertibleDebt		51,271us-gaap_AdjustmentsToAdditionalPaidInCapitalEquityComponentOfConvertibleDebt / us-gaap_StatementEquityComponentsAxis = us-gaap_AdditionalPaidInCapitalMember
Net income (loss)	12,024us-gaap_NetIncomeLoss				12,024us-gaap_NetIncomeLoss / us-gaap_StatementEquityComponentsAxis = us-gaap_RetainedEarningsMember
Net loss in noncontrolling interests	(1,132)us-gaap_NetIncomeLossAttributableToNoncontrollingInterest					(1,132)us-gaap_NetIncomeLossAttributableToNoncontrollingInterest / us-gaap_StatementEquityComponentsAxis = us-gaap_NoncontrollingInterestMember
Realized gain on sale of investments	(1,833)us-gaap_OtherComprehensiveIncomeLossReclassificationAdjustmentFromAOCIForSaleOfSecuritiesNetOfTax			(1,833)us-gaap_OtherComprehensiveIncomeLossReclassificationAdjustmentFromAOCIForSaleOfSecuritiesNetOfTax / us-gaap_StatementEquityComponentsAxis = us-gaap_AccumulatedOtherComprehensiveIncomeMember
Balance at end of period at Dec. 31, 2014	$ 24,408us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest	$ 20us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest / us-gaap_StatementEquityComponentsAxis = us-gaap_CommonStockMember	$ 680,660us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest / us-gaap_StatementEquityComponentsAxis = us-gaap_AdditionalPaidInCapitalMember	$ 4,953us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest / us-gaap_StatementEquityComponentsAxis = us-gaap_AccumulatedOtherComprehensiveIncomeMember	$ (659,315)us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest / us-gaap_StatementEquityComponentsAxis = us-gaap_RetainedEarningsMember	$ (1,910)us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest / us-gaap_StatementEquityComponentsAxis = us-gaap_NoncontrollingInterestMember	$ 0us-gaap_StockholdersEquityIncludingPortionAttributableToNoncontrollingInterest / us-gaap_StatementEquityComponentsAxis = us-gaap_TreasuryStockMember
Balance at end of period (in shares) at Dec. 31, 2014		19,575,150us-gaap_SharesOutstanding / us-gaap_StatementEquityComponentsAxis = us-gaap_CommonStockMember					0us-gaap_SharesOutstanding / us-gaap_StatementEquityComponentsAxis = us-gaap_TreasuryStockMember

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