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CONSOLIDATED STATEMENTS OF OPERATIONS - USD ($)
$ in Thousands
 12 Months Ended
Dec. 31, 2015
Dec. 31, 2014
Dec. 31, 2013
Revenues:      
Royalties $ 38,194 $ 29,994 $ 23,584
Material sales 27,662 28,488 19,072
License fees, milestones and other revenues 6,058 6,056 6,317
Total revenues 71,914 64,538 48,973
Operating costs and expenses:      
Cost of material sales 5,807 9,136 5,732
Research and development 13,380 12,122 9,274
General and administrative 24,378 22,570 17,984
Lease exit and termination costs 1,020 1,084 560
Write-off of acquired IPR&D 0 0 480
Total operating costs and expenses 44,585 44,912 34,030
Income from operations 27,329 19,626 14,943
Other (expense) income:      
Interest expense, net (11,802) (4,860) (2,077)
Increase in contingent liabilities (5,013) (5,135) (3,597)
Gain on deconsolidation of Viking 28,190 0 0
Equity in net losses from Viking (5,143) 0 0
Other, net 1,768 1,671 (63)
Total other income (expense), net 8,000 (8,324) (5,737)
Income from continuing operations before income tax benefit 35,329 11,302 9,206
Income tax benefit (expense) from continuing operations 219,596 (410) (374)
Income from continuing operations including noncontrolling interests 254,925 10,892 8,832
Less: Net loss attributable to noncontrolling interests (2,380) (1,132)  
Net income from continuing operations 257,305 12,024 8,832
Discontinued operations:      
Gain on sale of Avinza Product Line, net     2,588
Net income $ 257,305 $ 12,024 $ 11,420
Basic per share amounts:      
Income (loss) from continuing operations (in usd per share) $ 13.00 $ 0.59 $ 0.43
Income from discontinued operations (in usd per share)     0.13
Net income (loss) (in usd per share) $ 13.00 $ 0.59 $ 0.56
Weighted average number of common shares-basic (shares) 19,789,991 20,418,569 20,312,395
Diluted per share amounts:      
Income (loss) from continuing operations (in usd per share) $ 12.12 $ 0.56 $ 0.43
Income from discontinued operations (in usd per share)     0.12
Net income (loss) (in usd per share) $ 12.12 $ 0.56 $ 0.55
Weighted average number of common shares-diluted (shares) 21,227,887 21,433,178 20,745,454