Lease Obligations (Details) $ in Thousands	12 Months Ended
Dec. 31, 2015 USD ($)
Payments expected to received from sublease agreements
Operating lease obligation, Less than 1 year	$ 2,048
Operating lease obligation, 1-2 years	313
Operating leases obligation, 3-4 years	275
Operating lease obligation, Thereafter	341
Operating lease obligation, Total	2,977
Sublease payments expected to be received, Less than 1 year	1,762
Sublease payments expected to be received, 1-2 years	313
Sublease payments to be received, 3-4 years	275
Sublease payments to be received, Thereafter	341
Sublease payments expected to be received, Total	$ 2,691
Corporate Headquarters - La Jolla \| CALIFORNIA
Payments expected to received from sublease agreements
Lease Termination Date	Apr. 30, 2016
Operating lease obligation, Less than 1 year	$ 230
Operating lease obligation, Total	$ 230
Corporate Headquarters - San Diego, CA \| CALIFORNIA
Payments expected to received from sublease agreements
Lease Termination Date	Apr. 30, 2023
Operating lease obligation, Less than 1 year	$ 21
Operating lease obligation, 1-2 years	259
Operating leases obligation, 3-4 years	275
Operating lease obligation, Thereafter	341
Operating lease obligation, Total	$ 896
Bioscience and Technology Business Center - Lawrence, KS \| KANSAS
Payments expected to received from sublease agreements
Lease Termination Date	Dec. 01, 2017
Operating lease obligation, Less than 1 year	$ 54
Operating lease obligation, 1-2 years	54
Operating lease obligation, Total	$ 108
Vacated Office Office and Research Facility - Cranbury, NJ \| NEW JERSEY
Payments expected to received from sublease agreements
Lease Termination Date	Aug. 01, 2016
Operating lease obligation, Less than 1 year	$ 1,743
Operating lease obligation, Total	$ 1,743
Office and Research Facility - La Jolla, CA \| CALIFORNIA
Payments expected to received from sublease agreements
Lease Termination Date	Apr. 30, 2016
Sublease payments expected to be received, Less than 1 year	$ 145
Sublease payments expected to be received, Total	$ 145
Office and Research Facility - Cranbury, NJ \| NEW JERSEY
Payments expected to received from sublease agreements
Lease Termination Date	Aug. 01, 2016
Sublease payments expected to be received, Less than 1 year	$ 141
Sublease payments expected to be received, Total	$ 141

Operating Leases, Future Minimum Payments, Due After Four Years

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Operating Leases, Future Minimum Payments Due, Future Minimum Sublease Rentals, Due After Four Years

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Operating Leases, Future Minimum Payments Due, Future Minimum Sublease Rentals, Due Next Twelve Months

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Operating Leases, Future Minimum Payments Due, Future Minimum Sublease Rentals, Due in One and Two Years

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Operating Leases, Future Minimum Payments Due, Future Minimum Sublease Rentals, Due in Three and Four Years

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Amount of required minimum rental payments for leases having an initial or remaining non-cancelable letter-terms in excess of one year.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 840
-SubTopic 10
-Section 55
-Paragraph 40
-Subparagraph (Note 3)
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-Publisher FASB
-Name Accounting Standards Codification
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-Section 50
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Contractually required future rental payments receivable on noncancelable subleasing arrangements.

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Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 840
-SubTopic 20
-Section 50
-Paragraph 2
-Subparagraph (b)
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