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Stockholders' Equity (Details 1)
12 Months Ended
Dec. 31, 2015
$ / shares
shares
$8.58 – $12.53  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Range of exercise prices (per share), lower $ 8.58
Range of exercise prices (per share), upper $ 12.53
Options outstanding (shares) | shares 353,949
Weighted average remaining life in years 5 years 2 months 1 day
Weighted average exercise price (per share) $ 10.26
Options exercisable (shares) | shares 353,824
Weighted average exercise price (per share) $ 10.26
$12.81-16.14  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Range of exercise prices (per share), lower 12.81
Range of exercise prices (per share), upper $ 16.14
Options outstanding (shares) | shares 371,551
Weighted average remaining life in years 5 years 6 months 29 days
Weighted average exercise price (per share) $ 14.75
Options exercisable (shares) | shares 342,754
Weighted average exercise price (per share) $ 14.78
$17.10-32.30  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Range of exercise prices (per share), lower 17.10
Range of exercise prices (per share), upper $ 32.30
Options outstanding (shares) | shares 361,019
Weighted average remaining life in years 6 years 6 months 18 days
Weighted average exercise price (per share) $ 23.34
Options exercisable (shares) | shares 270,634
Weighted average exercise price (per share) $ 23.81
$32.76-74.42  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Range of exercise prices (per share), lower 32.76
Range of exercise prices (per share), upper $ 74.42
Options outstanding (shares) | shares 552,544
Weighted average remaining life in years 8 years 2 months 5 days
Weighted average exercise price (per share) $ 64.69
Options exercisable (shares) | shares 226,076
Weighted average exercise price (per share) $ 67.13
$89.75-104.59  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Range of exercise prices (per share), lower 89.75
Range of exercise prices (per share), upper $ 104.59
Options outstanding (shares) | shares 44,278
Weighted average remaining life in years 9 years 5 months 19 days
Weighted average exercise price (per share) $ 98.13
Options exercisable (shares) | shares 0
Weighted average exercise price (per share) $ 0.00
$8.58 - 104.59  
Share-based Compensation Arrangement by Share-based Payment Award [Line Items]  
Range of exercise prices (per share), lower 8.58
Range of exercise prices (per share), upper $ 104.59
Options outstanding (shares) | shares 1,683,341
Weighted average remaining life in years 6 years 7 months 28 days
Weighted average exercise price (per share) $ 34.23
Options exercisable (shares) | shares 1,193,288
Weighted average exercise price (per share) $ 25.41