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Significant Accounting Policies (Accounting for Share-Based Compensation) (Details) - USD ($) $ in Thousands | 3 Months Ended | 6 Months Ended
--- | --- | ---
Jun. 30, 2016 | Jun. 30, 2015 | Jun. 30, 2016 | Jun. 30, 2015
Basis of Presentation [Line Items] |  |  |  |
Share-based compensation expense total | $ 4,647 | $ 3,760 | $ 8,766 | $ 6,675
Research and development expenses |  |  |  |
Basis of Presentation [Line Items] |  |  |  |
Share-based compensation expense total | 2,089 | 1,253 | 3,674 | 2,174
General and administrative expenses |  |  |  |
Basis of Presentation [Line Items] |  |  |  |
Share-based compensation expense total | $ 2,558 | $ 2,507 | $ 5,092 | $ 4,501

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- Definition The amount of expense, net of income tax, recognized during the period arising from equity-based compensation arrangements (for example, shares of stock, unit, stock options or other equity instruments) with employees, directors and certain consultants qualifying for treatment as employees. + References No definition available. + Details
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