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Basis of Presentation and Significant Accounting Policies (Accounting for Share-Based Compensation) (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2016	Sep. 30, 2015	Sep. 30, 2016	Sep. 30, 2015
Basis of Presentation [Line Items]
Share-based compensation expense total	$ 5,331	$ 2,836	$ 13,690	$ 9,511
Research and development expenses
Basis of Presentation [Line Items]
Share-based compensation expense total	2,845	957	6,112	3,131
General and administrative expenses
Basis of Presentation [Line Items]
Share-based compensation expense total	$ 2,486	$ 1,879	$ 7,578	$ 6,380

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- Definition

Basis of presentation.

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- Definition

The amount of expense, net of income tax, recognized during the period arising from equity-based compensation arrangements (for example, shares of stock, unit, stock options or other equity instruments) with employees, directors and certain consultants qualifying for treatment as employees.

+ References

No definition available.

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