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Significant Accounting Policies (Accounting for Share-Based Compensation) (Details) - USD ($) $ in Thousands | 3 Months Ended
--- | ---
Mar. 31, 2016 | Mar. 31, 2015
Basis of Presentation [Line Items] |  |
Share-based compensation expense total | $ 4,118 | $ 2,914
Research and development expenses |  |
Basis of Presentation [Line Items] |  |
Share-based compensation expense total | 1,585 | 920
General and administrative expenses |  |
Basis of Presentation [Line Items] |  |
Share-based compensation expense total | $ 2,533 | $ 1,994

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- Definition The amount of expense, net of income tax, recognized during the period arising from equity-based compensation arrangements (for example, shares of stock, unit, stock options or other equity instruments) with employees, directors and certain consultants qualifying for treatment as employees. + References No definition available. + Details
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