    <SEC-DOCUMENT>0000886163-16-000164-index.html : 20160412
    <SEC-HEADER>0000886163-16-000164.hdr.sgml : 20160412
    <ACCEPTANCE-DATETIME>20160412160327
    ACCESSION NUMBER:		0000886163-16-000164
    CONFORMED SUBMISSION TYPE:	DEF 14A
    PUBLIC DOCUMENT COUNT:		11
    CONFORMED PERIOD OF REPORT:	20160412
    FILED AS OF DATE:		20160412
    DATE AS OF CHANGE:		20160412
    EFFECTIVENESS DATE:		20160412

    FILER:

    	COMPANY DATA:
    		COMPANY CONFORMED NAME:			LIGAND PHARMACEUTICALS INC
    		CENTRAL INDEX KEY:			0000886163
    		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
    		IRS NUMBER:				770160744
    		STATE OF INCORPORATION:			DE
    		FISCAL YEAR END:			1231

    	FILING VALUES:
    		FORM TYPE:		DEF 14A
    		SEC ACT:		1934 Act
    		SEC FILE NUMBER:	001-33093
    		FILM NUMBER:		161567293

    	BUSINESS ADDRESS:
    		STREET 1:		11119 NORTH TORREY PINES ROAD
    		STREET 2:		SUITE 200
    		CITY:			LA JOLLA
    		STATE:			CA
    		ZIP:			92037
    		BUSINESS PHONE:		858-550-7500

    	MAIL ADDRESS:
    		STREET 1:		11119 NORTH TORREY PINES ROAD
    		STREET 2:		SUITE 200
    		CITY:			LA JOLLA
    		STATE:			CA
    		ZIP:			92037
    </SEC-HEADER>
    <DOCUMENT>
    <TYPE>DEF 14A
    <SEQUENCE>1
    <FILENAME>lgnd-2016annualmeetingprox.htm
    <DESCRIPTION>DEF 14A
    <TEXT>
    Document 1 - file: lgnd-2016annualmeetingprox.htm

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    <TYPE>GRAPHIC
    <SEQUENCE>2
    <FILENAME>a02bfceligandpharmacommo001.jpg
    <TEXT>
    Document 2 - file: a02bfceligandpharmacommo001.jpg

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    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>3
    <FILENAME>a02bfceligandpharmacommo002.jpg
    <TEXT>
    Document 3 - file: a02bfceligandpharmacommo002.jpg

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    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>4
    <FILENAME>a02bffbligandpharmanotic001.jpg
    <TEXT>
    Document 4 - file: a02bffbligandpharmanotic001.jpg

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    <DOCUMENT>
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    <SEQUENCE>5
    <FILENAME>a02bffbligandpharmanotic002.jpg
    <TEXT>
    Document 5 - file: a02bffbligandpharmanotic002.jpg

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    <SEQUENCE>6
    <FILENAME>image0.jpg
    <TEXT>
    Document 6 - file: image0.jpg

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    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>7
    <FILENAME>image1a01.gif
    <TEXT>
    Document 7 - file: image1a01.gif

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    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>8
    <FILENAME>image2.gif
    <TEXT>
    Document 8 - file: image2.gif

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    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>9
    <FILENAME>image3.gif
    <TEXT>
    Document 9 - file: image3.gif

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    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>10
    <FILENAME>image4.gif
    <TEXT>
    Document 10 - file: image4.gif

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    <DOCUMENT>
    <TYPE>GRAPHIC
    <SEQUENCE>11
    <FILENAME>image5.jpg
    <TEXT>
    Document 11 - file: image5.jpg

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    </SEC-DOCUMENT>