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Fair Value Measurements (Tables)
6 Months Ended
Jun. 30, 2018
Fair Value Disclosures [Abstract]  
Schedule of Assets and Liabilities Measured at Fair Value on Recurring Basis
The following table presents the Company's hierarchy for assets and liabilities measured at fair value.
 
 
June 30, 2018
 
December 31, 2017
 
 
Level 1
 
Level 2
 
Level 3
 
Total
 
Level 1
 
Level 2
 
Level 3
 
Total
Assets:
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Short-term investments(1)
 
$
61,393

 
$
803,871

 
$

 
$
865,264

 
$
1,896

 
$
179,145

 
$

 
$
181,041

Note receivable Viking
 

 

 

 

 

 

 
3,877

 
3,877

Investment in warrants (2)
 
12,296

 

 

 
12,296

 
3,846

 

 

 
3,846

     Total assets
 
$
73,689

 
$
803,871

 
$

 
$
877,560

 
$
5,742

 
$
179,145

 
$
3,877

 
$
188,764

Liabilities:
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
Current portion of contingent liabilities - Crystal (3)

 
$

 
$

 
$
3,618

 
$
3,618

 
$

 
$

 
$
4,618

 
4,618

Current contingent liabilities-CyDex (4)
 

 

 
36

 
36

 

 

 
86

 
86

Long-term portion of contingent liabilities - Crystal (3)

 

 

 
3,784

 
3,784

 

 

 
3,783

 
3,783

Long-term contingent liabilities-CyDex (4)
 

 

 
1,503

 
1,503

 

 

 
1,503

 
1,503

Long-term contingent liabilities-Metabasis (5)
 

 
2,859

 

 
2,859

 

 
3,971

 

 
3,971

     Total liabilities
 
$

 
$
2,859

 
$
8,941

 
$
11,800

 
$

 
$
3,971

 
$
9,990

 
$
13,961


(1)
Investments in equity securities, which the Company received from Viking and another licensee as upfront and event-based payments, are classified as level 1 as the fair value is determined using quoted market prices in active markets for the same securities. Short-term investments in marketable debt securities with maturities greater than 90 days are classified as level 2 of the fair value hierarchy, as these investment securities are valued based upon quoted prices for identical or similar instruments in markets that are not active, and model-based valuation techniques for which all significant assumptions are observable in the market. 
(2)
Investment in warrants, which the Company received as a result of Viking’s partial repayment of the Viking note receivable and the Company’s purchase of Viking common stock and warrants in April 2016, are classified as level 1 as the fair value is determined using quoted market prices in active markets for the same securities. The change of the fair value is recorded in Gain (loss) from Viking in the Company's condensed consolidated statement of operations.
(3)
The fair value of Crystal contingent liabilities was determined using a probability weighted income approach. Most of the contingent payments are based on development or regulatory milestones as defined in the merger agreement with Crystal. The fair value is subjective and is affected by changes in inputs to the valuation model including management’s estimates regarding the timing and probability of achievement of certain developmental and regulatory milestones. At June 30, 2018, most of the development and regulatory milestones were estimated to be highly probable of being achieved between 2018 and 2019. Changes in these estimates may materially affect the fair value.
(4)
The fair value of the liabilities for CyDex contingent liabilities were determined based on the income approach. To the extent the estimated future income may vary significantly given the long-term nature of the estimate, the Company utilizes a Monte Carlo model. The fair value is subjective and is affected by changes in inputs to the valuation model including management’s estimates of timing and probability of achievement of certain revenue thresholds and developmental and regulatory milestones which may be achieved and affect amounts owed to former license holders. Changes in these assumptions can materially affect the fair value estimate.
(5)
The liability for CVRs for Metabasis are determined using quoted prices in a market that is not active for the underlying CVR. At June 30, 2018, the Company has a CVR payable of $3.8 million to the Glucagon CVR holders due on July 2, 2018, which is not included in the fair value disclosure.

Schedule of CyDex Acquisition
The following table represents significant unobservable inputs used in determining the fair value of contingent liabilities assumed in the acquisition of CyDex:
 
June 30, 2018
 
December 31, 2017
Revenue volatility
25%
 
25%
Average probability of commercialization
12.5%
 
12.5%
Market price of risk
2.9%
 
2.9%